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CenGEM

CenGEM

Advancing new therapies for Friedreich ataxia heart disease
Funder: National Health and Medical Research Council
Duration: February 2024 - February 2027
Identification of therapeutic targets in MNX1-rearranged infant Acute Myeloid Leukaemia
Funder: CCLG - Little Princess Trust
Duration: October 2023 - September 2025
Nottingham Impact Bio-Accelerator Award
Funder: The University of Nottingham
Duration: June 2023 - October 2023

Seed funding to explore a potential new biotechnology/diagnostic application arising as an idea from recent CRISPR work

Smart Portable and Fast Acute Myocardial Infarction Detection Device for Ambulance Crew Use
Funder: Engineering and Physical Sciences Research Council
Duration: April 2023 - September 2024

In a ground-breaking stride towards revolutionizing cardiac emergency care, Professor Wamadeva Balachandran and his illustrious team at Brunel University London, in collaboration with Harefield Hospital, are spearheading the development of an innovative, life-saving device. This compact, pioneering technology stands poised to transform the way heart attacks are detected – swiftly and accurately, even before a patient reaches the hospital. This remarkable innovation is more than a leap in medical technology; it's a testament to the relentless pursuit of excellence and compassion in healthcare. As this device moves closer to becoming a staple in ambulances, it holds the promise of safeguarding hearts and saving lives, heralding a new era of responsive and advanced emergency cardiac care.

Modelling infant AML using an organoid model of embryonic haematopoiesis
Funder: Lady Tata Memorial Trust
Duration: October 2022 - September 2024

PhD studentship to Ayona Johns

How bacteria replicate their DNA in spite of barriers one molecule at a time
Funder: Biotechnology & Biological Sciences Research Council
Duration: April 2022 - March 2025
IDENTIFICATION OF THE MOLECULAR PATHWAYS LINKING H2A.Z (H2AZ.1 and H2AZ.2) TO CHROMOSOME SEGREGATION FIDELITY
Funder: Biotechnology & Biological Sciences Research Council
Duration: February 2022 - January 2025
Haematopoietic stem cells gene therapy for the treatment of Friedreich’s Ataxia
Funder: Friedreich’s Ataxia Research Alliance (FARA)
Duration: January 2022 - January 2024
Phenotyping and Cell Sorting Laboratory
Funder: Wolfson Foundation
Duration: January 2022 - December 2023

equipment grant

Sphingolipid Rheostat as a Potential Target for Friedreich’s Ataxia
Funder: Friedreich's Ataxia Research Alliance
Duration: October 2021 - October 2023
Functional Analysis of two colorectal cancer risk loci on chromosome 11: POLD3
Funder: Bowel Research UK
Duration: October 2021 - September 2024

An investigation of the role of two novel candidate risk genes in colorectal cancer, and how common DNA variants may change the expression of these genes.

Targeting prolyl isomerases as a therapeutic approach for multiple myeloma
Funder: Kay Kendall Leukaemia Fund
Duration: January 2021 - January 2024
Investigating the role of bioactive sphingolipids in Friedreich’s ataxia (FRDA)
Funder: Ataxia UK
Duration: January 2021 - July 2021

Project Grant

Starving livers of glucose for HCC prevention and treatment
Funder: Guts UK
Duration: November 2020 - November 2022
COVID-Secure High Street Work Stores
Funder: Innovate UK
Duration: October 2020 - March 2021
Visiting Research Grant
Funder: Universitat de les Illes Balears
Duration: September 2020 - July 2021
Understanding how an MLH1 promoter polymorphism predisposes to colorectal cancer
Funder: Medical Research Council
Duration: June 2020 - October 2021
Combinatorial Effects of Histone and DNA Methylation in Acute Myeloid Leukaemia
Funder: British Society for Haematology
Duration: March 2020 - February 2021

Early Stage Research Set-Up Grant

COMBINATORIAL EFFECTS OF HISTONE AND DNA METHYLATION IN ACUTE MYELOID LEUKAEMIA
Funder: British Society for Haematology
Duration: March 2020 - February 2021
Building CRISPR Immunity Systems - How is Invading DNA Captured?
Funder: Biotechnology & Biological Sciences Research Council
Duration: February 2020 - January 2023
Progeria Family Circle UK
Funder:
Duration: -
Advancing Tools for Human Early Lifecourse Exposome research and Translation: ATHLETE
Funder: European Commission
Duration: January 2020 - December 2024
Investigating the role of the MYCN-cdca2 axis in neuroblastoma.
Funder: Kidscan
Duration: October 2019 - September 2022
Studying novel endocrine signals in the human placenta (PhD studentship - Kerslake - Stipend)
Funder: Cancer Treatment and Research Trust
Duration: October 2019 - September 2022
Studying novel endocrine signals in the human placenta (PhD studentship - Kerslake - RSTG support)
Funder: University Hospitals Coventry & Warwickshire NHS Trust
Duration: October 2019 - March 2023
Comprehensive phosphoproteome analysis of Friedreich’s ataxia cells
Funder: Brunel BRIEF Award
Duration: September 2019 - September 2021
A new cell and gene therapy approach for Friedreich's ataxia
Funder: Medical Research Council
Duration: May 2019 - April 2021
RNA composition of exosomes as potential biomarkers for cancer
Funder: Elva-1
Duration: May 2019 - April 2020
HBM4EU - European Human Biomonitoring Initiative
Funder: European Commission
Duration: March 2019 - December 2021
Data collection in support of the Endocrine Disruption (ED) assessment for non-target vertebrates
Funder: European Food Safety Authority
Duration: February 2019 - February 2020
Defining and exploiting the role of non-genetic variability in cancer biology
Funder: Wellcome Trust / University of Cambridge Institutional Strategic Support Fund
Duration: January 2019 - June 2020

Personal Fellowship