Brunel Health

Brunel University London has world-class expertise in working with health sector stakeholders, finding solutions to develop better health outcomes and innovations in Medical and Health Sciences, Biosciences, Life Sciences, Biomedical Technology and Digital Health.

Our expertise areas

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Biomedical Technology

Our Biomedical Engineering research is interdisciplinary, using the skills and knowledge of academics from Engineering and Life Sciences. Research and development are being conducted in different areas including diagnostics, cardiovascular mechanics, organ-on-a-chip, prosthetics and diabetes. This has led to the development of smart devices for rapid screening, monitoring, diagnosis and therapy of diseases at the point of care and/or in laboratory settings.

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Cancer and Cell Biology

Our cell and molecular biologists are striving to understand the mechanisms that keep our cells healthy, and how these can be disrupted; e.g. in cancer through the chromosomal aberrations that can arise as a consequence of exposure to radiation.

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Digital Health

We have the expertise in digital health areas such as Bioinformatics, Computational Medicine, Medical and Health Data Analytics, Modelling and Simulations, Immersive Data Visualisation, Assurance, Security, Provenance of medical Data, Multi-Sensorial Technologies for Medical Applications and Data Driven Health Service Productivity.

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Environmental Toxicology

Our research explores how harmful chemical mixtures in the environment can disrupt hormonal processes and should be considered as global health hazards. Working with regulatory bodies, we have developed a new approach to assessing the risks of these environmental pollutants.

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Genetics and Genomics

Our researchers use sophisticated laboratory techniques and "big data" analytic methods to examine genetic influences on health and disease, and assess the safety of novel gene therapies.

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Health Promotion, Policy and Economics

We have pioneered the development of methods to assess the cost-effectiveness of health interventions, and we carry out innovative research on health promotion and understanding behaviour change (e.g. in relation to smoking cessation and breastfeeding promotion programmes).

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Human Well-Being, Development and Ageing

We carry out pioneering multi-disciplinary research on factors affecting well-being and health across the lifespan, including child development, mental health and issues affecting older people. Our research examines the importance of physical activity and sports participation, religious and spiritual beliefs, cultural factors, inequality, rehabilitation and educational interventions.

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Inflammation and Immunity

To enhance human health, we are using multidisciplinary approaches to explore the inflammation and immunes processes involved in cardiovascular diseases –with a focus on identifying targets for drug development and diagnosis, leading to improved prevention and treatment.

Browse our research projects

Colourful fluorescent microscopy image showing cells with blue nuclei and green and red fluorescence.

Cellular senescence and its impact on organismal ageing

Fluorescent microscopic image showing cells with bright blue nuclei and green cytoplasm.

Investigating variations in two genes that increase the risk of bowel cancer

A woman bathing a child outdoors

How the Schistosoma mansoni parasite manipulates its hosts' genomes

3D illustration of x-chromosomes on a blue background thumbnail

Chromosome behaviour and dynamics after exposure to simulated microgravity

nurse holding a heart

Using creative engagement to support healthcare workers

school meals

Sustainable and healthy school food environments in Brazil

Older man sitting

Improving health in older adults by reducing sitting time

chromosone

How do cells divide?

heart organs

Investigating thrombo-inflammation associated with cardiovascular diseases

sickle cell

Promoting inflammation resolution in sickle cell disease

neutrophils

Pharmacological strategies for resolution of inflammation

blood cells

Understanding and manipulating our immune system to protect against ageing

children in wheelchair

A new cell and gene therapy approach for Friedreich's ataxia

upper-body scan

Host-pathogen interactions in tuberculosis

human body

Human endogenous factors in the control of mycobacterial infection

aerial view of Brunel University London campus

Improving the efficacy of immunotherapies for the childhood cancer neuroblastoma

Healthcare in the Metaverse

Governing immersive biomedical tech, health and human rights in the Metaverse

Digital histopathology image of microscope alongside computer with monitor showing a scan

Innovate photonic devices for digital histopathology

Leg muscle being heated in a laboratory setting

Understanding the role of temperature on muscle function in older adults

Home exercise with laptop

Post-Covid lifestyle and mental wellbeing

bone marrow

Modelling internal bone marrow dose from Radium-223

man in lab

Evaluation of oligonucleotides for therapy of Friedreich ataxia

disabled child in wheelchair

Identifying the most potent and effective treatment of Friedreich ataxia

Colour burst head

Rapid evidence scoping review: Creativity and Pathways to Subjective Wellbeing

SmartSocks

Can SmartSocks™ help deliver care to people with dementia living in care homes?

Risperidone tablets

Individual-level stroke risk prediction after risperidone treatment in dementia

dna strands

Side effects of gene therapy vectors

yoga

Cancer and physical activity

Protein phosphatase

The maintenance of genome integrity

mother holding a sick child

The role of CDCA2 molecule in neuroblastoma

microscope image

Genetic and cytogenetic family trio study

genetic research

Towards a therapy for Friedreich’s Ataxia

sphingolipid

Investigating the role of bioactive sphingolipids in Friedreich’s ataxia

Nerve tissue

Elucidation of the metabolic signature of Friedreich's ataxia

medic in lab

Metabolic reprogramming for improved BCG vaccine efficacy

Animal research lab

Early growth protein molecules and preventing autoimmune disease and cancer

man in lab

Engineering tissue specific scaffolds for organ-on-a-chip models

petri dish

Vagina-on-a-Chip

chicken app

Low-cost portable molecular diagnostic platform

structure of inner ear with implant

Innovative techniques for precise, atraumatic placement of cochlear implant

barren landscape

Social, ecological, political, and cultural implications of extinction

microscope image of cells

Modelling infant leukaemia using gene editing technology

india street

Air pollution, brain health and wellbeing in India

woman with no sense of smell

Recovering sense of smell and taste

eel fishing

Optimising eel conservation efforts

Photo of a Mauritius landscape edited so that the church is blanked out

Understanding the causes of atheism in Mauritius

lab

Endocrine disruptors linked to developmental neurotoxicity

chemical pollution

Predicting chemical bioaccumulation in wildlife using machine learning

blood samples

Reactivation of herpesviruses in Myalgic Encephalomyelitis

doctor looking at medical data

Detecting change in medical data to identify bias

cells

Common genetic variants that increase the risk of cancer

cancer

Does CRISPR-Cas9 treatment cause DNA damage in cancer cells?

Biosciences

Modelling adenoid cystic carcinoma in a mouse

cancer cells

Oncoprotein MYB in the head and neck cancer adenoid cystic carcinoma

radiation screenshot

Radiation exposure and heritable genetic effects

running man

Culture, sport and wellbeing evidence review

biomedical equipment

Cell signalling aimed at regulating cell proliferation

miscroscope

Multifactorial impacts on early breast carcinogenesis

Biosciences tools

Use of liquid biopsies as cancer biomarkers

lab work

Organ-on-a-chip models for ovarian cancer

dna strand

Aberrant genome organisation in female cancers

woman sitting on sofa and eating

Diabetes UK: Understanding physical activity

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Physical activity in the workplace

young people

Change Makers - Brunel Youth Action Group

stroke

Investigating cerebral microvasculature dysfunction in stroke

Parasitology slide of Schistosoma

Reducing the risk of human infection to Schistosomiasis

atheism

Explaining the causes of atheism and non-belief

cows

Innate immunity in bovine tuberculosis

red blood cells

Big Tissue and Society

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