Professor Andreas Kortenkamp
Professor - Human Molecular Toxicology
Heinz Wolff 001E
- Email: andreas.kortenkamp@brunel.ac.uk
- Tel: +44 (0)1895 266525
- Environmental Sciences
- Department of Life Sciences
- College of Health, Medicine and Life Sciences
Kabil, A., Silva, E. and Kortenkamp, A. (2008) 'Estrogens and genomic instability in human breast cancer cells - Involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals'. Carcinogenesis, 29 (10). pp. 1862 - 1868. ISSN: 0143-3334 Open Access Link
Christiansen, S., Scholze, M., Axelstad, M., Boberg, J., Kortenkamp, A. and Hass, U. (2008) 'Combined exposure to anti-androgens causes markedly increased frequencies of hypospadias in the rat'. International Journal of Andrology, 31 (2). pp. 241 - 248. ISSN: 0105-6263
Johnson, AC., Jürgens, MD., Williams, RJ., Kümmerer, K., Kortenkamp, A. and Sumpter, JP. (2008) 'Do cytotoxic chemotherapy drugs discharged into rivers pose a risk to the environment and human health? An overview and UK case study'. Journal of Hydrology, 348 (1-2). pp. 167 - 175. ISSN: 0022-1694
Kortenkamp, A. (2008) 'Low dose mixture effects of endocrine disrupters: Implications for risk assessment and epidemiology'. International Journal of Andrology, 31 (2). pp. 233 - 240. ISSN: 0105-6263
Christiansen, S., Axelstad, M., Kortenkamp, A., Stolze, M. and Hass, U. (2007) 'Combined exposure to dissimilarly acting anti-androgens causes markedly increased frequency of hypospadias in the rat'. Toxicology Letters, 172. pp. S179 - S179. ISSN: 0378-4274
Heinrich, M., Modarai, M. and Kortenkamp, A. (2007) 'CYP inhibitory action of Echinacea preparations differs widely, but is it clinically relevant?'.55th Annual Congress of the Society-for-Medicinal-Plant-Research. Karl Franzens Univ, Graz, AUSTRIA. 2 - 6 September. GEORG THIEME VERLAG KG. pp. 823 - 823. ISSN: 0032-0943
Modarai, M., Wilson, N., Politi, M., Suter, A., Kortenkamp, A. and Heinrich, M. (2007) 'Evaluating CYP3A4 inhibitory activity of Echinacea extracts using NMR and multivariate data analysis'.55th Annual Congress of the Society-for-Medicinal-Plant-Research. Karl Franzens Univ, Graz, AUSTRIA. 2 - 6 September. GEORG THIEME VERLAG KG. pp. 990 - 991. ISSN: 0032-0943
Metzdorff, SB., Dalgaard, M., Christiansen, S., Axelstad, M., Hass, U., Kiersgaard, MK., et al. (2007) 'Dysgenesis and histological changes of genitals and perturbations of gene expression in male rats after in utero exposure to antiandrogen mixtures'. Toxicological Sciences, 98 (1). pp. 87 - 98. ISSN: 1096-6080
Modarai, M., Gertsch, J., Suter, A., Heinrich, M. and Kortenkamp, A. (2007) 'Cytochrome P450 inhibitory action of Echinacea preparations differs widely and co-varies with alkylamide content'. Journal of Pharmacy and Pharmacology, 59 (4). pp. 567 - 573. ISSN: 0022-3573
Silva, E., Scholze, M. and Kortenkamp, A. (2007) 'Activity of xenoestrogens at nanomolar concentrations in the E-screen assay'. Environmental Health Perspectives, 115 (SUPPL1). pp. 91 - 97. ISSN: 0091-6765 Open Access Link
Kortenkamp, A. (2007) 'Introduction: Endocrine disruptors-exposure assessment, novel end points, and low-dose and mixture effects'. Environmental Health Perspectives, 115 (SUPPL1). pp. 7 - 7. ISSN: 0091-6765 Open Access Link
Scholze, M. and Kortenkamp, A. (2007) 'Statistical power considerations show the endocrine disruptor low-dose issue in a new light'. Environmental Health Perspectives, 115 (SUPPL1). pp. 84 - 90. ISSN: 0091-6765 Open Access Link
Hass, U., Scholze, M., Christiansen, S., Dalgaard, M., Vinggaard, AM., Axelstad, M., et al. (2007) 'Combined exposure to anti-androgens exacerbates disruption of sexual differentiation in the rat'. Environmental Health Perspectives, 115 (SUPPL1). pp. 122 - 128. ISSN: 0091-6765 Open Access Link
Brian, JV., Harris, CA., Scholze, M., Kortenkamp, A., Booy, P., Lamoree, M., et al. (2007) 'Evidence of estrogenic mixture effects on the reproductive performance of fish'. International Journal of Environmental Science and Technology, 41 (1). pp. 337 - 344. ISSN: 0013-936X Open Access Link
Kortenkamp, A., Faust, M., Scholze, M. and Backhaus, T. (2007) 'Low-level exposure to multiple chemicals: Reason for human health concerns?'. Environmental Health Perspectives, 115 (SUPPL1). pp. 106 - 114. ISSN: 0091-6765 Open Access Link
Modarai, M., Wilson, N., Politi, M., Suter, A., Kortenkamp, A. and Heinrich, M. (2007) 'Echinacea liquid formulations - NMR spectroscopy and multivariate data analysis of fractions with CYP3A4 inhibitory activity'. JOURNAL OF PHARMACY AND PHARMACOLOGY, 59. pp. A63 - A63. ISSN: 0022-3573
Heinrich, M., Modarai, M. and Kortenkamp, A. (2007) 'Drug interactions with Echinacea: does it matter how the product is made?'. JOURNAL OF PHARMACY AND PHARMACOLOGY, 59. pp. A80 - A80. ISSN: 0022-3573
Kortenkamp, A. (2007) 'Ten years of mixing cocktails: A review of combination effects of endocrine-disrupting chemicals'. Environmental Health Perspectives, 115 (SUPPL1). pp. 98 - 105. ISSN: 0091-6765 Open Access Link
Silva, E., Lopez-Espinosa, MJ., Molina-Molina, JM., Fernández, M., Olea, N. and Kortenkamp, A. (2006) 'Lack of activity of cadmium in in vitro estrogenicity assays'. Toxicology and Applied Pharmacology, 216 (1). pp. 20 - 28. ISSN: 0041-008X
Modarai, M., Gertsch, J., Suter, A., Kortenkamp, A. and Heinrich, M. (2006) 'Echinacea and its alkamides - An assessment of potential CYP-P450 enzyme inhibition?'.54th Annual Congress on Medicinal Plant Research. Helsinki, FINLAND. 29 - 2 September. GEORG THIEME VERLAG KG. pp. 1068 - 1068. ISSN: 0032-0943
Kortenkamp, A., Olea, N. and De Muinck Keizer-Schrama, S. (2006) 'Breast cancer, oestrogens and environmental pollutants: A re-evaluation from a mixture perspective'. International Journal of Andrology, 29 (1). pp. 193 - 198. ISSN: 0105-6263
Sumpter, JP., Johnson, AC., Williams, RJ., Kortenkamp, A. and Scholze, M. (2006) 'Modeling effects of mixtures of endocrine disrupting chemicals at the river catchment scale'. Environmental Science and Technology, 40 (17). pp. 5478 - 5489. ISSN: 0013-936X
Rajapakse, N., Butterworth, M. and Kortenkamp, A. (2005) 'Detection of DNA strand breaks and oxidized DNA bases at the single-cell level resulting from exposure to estradiol and hydroxylated metabolites'. Environmental and Molecular Mutagenesis, 45 (4). pp. 397 - 404. ISSN: 0893-6692
Schulte-Oehlmann, U. and Kortenkamp, A. (2005) 'The Prague declaration on endocrine disruption'. Environmental Science and Pollution Research, 12 (4). pp. 188. ISSN: 0944-1344
Rajapakse, N., Silva, E., Scholze, M. and Kortenkamp, A. (2004) 'Deviation from additivity with estrogenic mixtures containing 4-nonylphenol and 4-tert-octylphenol detected in the E-SCREEN assay'. Environmental Science and Technology, 38 (23). pp. 6343 - 6352. ISSN: 0013-936X
Peck, M., Gibson, RW., Kortenkamp, A. and Hill, EM. (2004) 'Sediments are major sinks of steroidal estrogens in two United Kingdom rivers'. Environmental Toxicology and Chemistry, 23 (4). pp. 945 - 952. ISSN: 0730-7268
Shayer, R., Kinchesh, P., Raffray, M. and Kortenkamp, A. (2004) 'Biomonitoring of chromium(VI) deposited in pulmonary tissues: Pilot studies of a magnetic resonance imaging technique in a post-mortem rodent model'. Biomarkers, 9 (1). pp. 32 - 46. ISSN: 1354-750X
Tang, S., Bremner, P., Kortenkamp, A., Schlage, C., Gray, AI., Gibbons, S. and et al. (2003) 'Biflavonoids with cytotoxic and antibacterial activity from Ochna macrocalyx'. Planta Medica, 69 (3). pp. 247 - 253. ISSN: 0032-0943
Rajapakse, N., Silva, E. and Kortenkamp, A. (2002) 'Combining xenoestrogens at levels below individual no-observed-effect concentrations dramatically enhances steroid hormone action'. Environmental Health Perspectives, 110 (9). pp. 917 - 921. ISSN: 1552-9924 Open Access Link
Silva, E., Rajapakse, N. and Kortenkamp, A. (2002) 'Something from "nothing" - Eight weak estrogenic chemicals combined at concentrations below NOECs produce significant mixture effects'. Environmental Science and Technology, 36 (8). pp. 1751 - 1756. ISSN: 0013-936X
Rajapakse, N., Ong, D. and Kortenkamp, A. (2001) 'Defining the impact of weakly estrogenic chemicals on the action of steroidal estrogens'. Toxicological Sciences, 60 (2). pp. 296 - 304. ISSN: 1096-6080
Payne, J., Scholze, M. and Kortenkamp, A. (2001) 'Mixtures of four organochlorines enhance human breast cancer cell proliferation'. Environmental Health Perspectives, 109 (4). pp. 391 - 397. ISSN: 0091-6765 Open Access Link
Payne, J., Jones, C., Lakhani, S. and Kortenkamp, A. (2000) 'Improving the reproducibility of the MCF-7 cell proliferation assay for the detection of xenoestrogens'. Science of the Total Environment, 248 (1). pp. 51 - 62. ISSN: 0048-9697
Jones, C., Payne, J., Wells, D., Delhanty, JDA., Lakhani, SR. and Kortenkamp, A. (2000) 'Comparative genomic hybridization reveals extensive variation among different MCF-7 cell stocks'. Cancer Genetics and Cytogenetics, 117 (2). pp. 153 - 158. ISSN: 0165-4608
Jones, C. and Kortenkamp, A. (2000) 'RAPD library fingerprinting of bacterial and human DNA: Applications in mutation detection'. Teratogenesis Carcinogenesis and Mutagenesis, 20 (2). pp. 49 - 63. ISSN: 0270-3211
Payne, J., Rajapakse, N., Wilkins, M. and Kortenkamp, A. (2000) 'Prediction and assessment of the effects of mixtures of four xenoestrogens'. Environmental Health Perspectives, 108 (10). pp. 983 - 987. ISSN: 0091-6765 Open Access Link
Rajapakse, N. and Kortenkamp, A. (1999) 'Formation of DNA damage by 17 β-oestradiol in MCI-7 breast cancer cells'. Journal of Pharmacy and Pharmacology, 51 (SUPPL.). pp. 151. ISSN: 0022-3573
Casadevall, M., Da Cruz Fresco, P. and Kortenkamp, A. (1999) 'Chromium(VI)-mediated DNA damage: Oxidative pathways resulting in the formation of DNA breaks and abasic sites'. Chemico-Biological Interactions, 123 (2). pp. 117 - 132. ISSN: 0009-2797
Kortenkamp, A. and Altenburger, R. (1999) 'Approaches to assessing combination effects of oestrogenic environmental pollutants'. Science of the Total Environment, 233 (1-3). pp. 131 - 140. ISSN: 0048-9697
Kortenkamp, A. and Altenburger, R. (1998) 'Synergisms with mixtures of xenoestrogens: A reevaluation using the method of isoboles'. Science of the Total Environment, 221 (1). pp. 59 - 73. ISSN: 0048-9697
Kortenkamp, A. (1998) 'Chromium biomonitoring - Achievements, problems, and future challenges'.2nd International Symposium on Metals and Genetics. TORONTO, CANADA. 26 - 29 May. KLUWER ACADEMIC/PLENUM PUBL. pp. 87 - 100.
Kortenkamp, A., Jones, C. and Baker, J. (1997) 'Genotypic selection of mutated DNA sequences using mismatch cleavage analysis, a possible basis for novel mutation assays'. Mutagenesis, 12 (5). pp. 335 - 338. ISSN: 0267-8357
Kortenkamp, A. (1997) 'Problems in the biological monitoring of chromium(VI) exposed individuals'. Biomarkers, 2 (2). pp. 73 - 79. ISSN: 1354-750X
Kortenkamp, A. (1996) 'Pharmacokinetic modelling in chromium risk assessment - A prediction of chromium (III) accumulation in humans from chromium dietary supplements - Comment'. HUMAN & EXPERIMENTAL TOXICOLOGY, 15 (7). pp. 601 - 602. ISSN: 0144-5952
Kortenkamp, A., Casadevall, M., DaCruzFresco, P. and Shayer, ROJ. (1996) 'Pathways in the chromium(VI)-mediated formation of DNA lesions: A review'.NATO Advanced Study Institute on Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment. PRZESIEKA, POLAND. 15 - 26 June. KLUWER ACADEMIC PUBL. pp. 15 - 34.
Kortenkamp, A. (1996) 'Approaches to the biological monitoring of chromium(VI) exposed individuals'.NATO Advanced Study Institute on Cytotoxic, Mutagenic and Carcinogenic Potential of Heavy Metals Related to Human Environment. PRZESIEKA, POLAND. 15 - 26 June. KLUWER ACADEMIC PUBL. pp. 35 - 53.
Kortenkamp, A., Casadevall, M., Faux, SP., Jenner, A., Shayer, ROJ., Woodbridge, N. and et al. (1996) 'A role for molecular oxygen in the formation of DNA damage during the reduction of the carcinogen chromium(VI) by glutathione'. Archives of Biochemistry and Biophysics, 329 (2). pp. 199 - 207. ISSN: 0003-9861
Kortenkamp, A., Casadevall, M. and Da Cruz Fresco, P. (1996) 'The reductive conversion of the carcinogen chromium (VI) and its role in the formation of DNA lesions'. Annals of Clinical and Laboratory Science, 26 (2). pp. 160 - 175. ISSN: 0091-7370
Casadevall, M. and Kortenkamp, A. (1995) 'The formation of both apurinic/apyrimidinic sites and single-strand breaks by chromate and glutathione arises from attack by the same single reactive species and is dependent on molecular oxygen'. Carcinogenesis, 16 (4). pp. 805 - 809. ISSN: 0143-3334
Cruz Fresco, PD., Shacker, F. and Kortenkamp, A. (1995) 'The Reductive Conversion of Chromium(VI) by Ascorbate Gives Rise to Apurinic/Apyrimidinic Sites in Isolated DNA'. Chemical Research in Toxicology, 8 (6). pp. 884 - 890. ISSN: 0893-228X
Da Cruz Fresco, P. and Kortenkamp, A. (1994) 'The formation of DNA cleaving species during the reduction of chromate by ascorbate'. Carcinogenesis, 15 (9). pp. 1773 - 1778. ISSN: 0143-3334