Professor Felicity Gavins
Professor - Pharmacology
Heinz Wolff 111
- Email: felicity.gavins@brunel.ac.uk
- Tel: +44 (0)1895 267151
Ahmad, I., Omura, S., Sato, F., Park, A-M., Khadka, S., Gavins, FNE., et al. (2024) 'Exploring the Role of Platelets in Virus-Induced Inflammatory Demyelinating Disease and Myocarditis'. International Journal of Molecular Sciences, 25 (6). pp. 1 - 25. ISSN: 1661-6596 Open Access Link
Gerke, V., Gavins, FNE., Geisow, M., Grewal, T., Jaiswal, JK., Nylandsted, J. and et al. (2024) 'Annexins-a family of proteins with distinctive tastes for cell signaling and membrane dynamics'. Nature communications, 15 (1). pp. 1 - 15. ISSN: 2041-1723 Open Access Link
Sparkenbaugh, EM., Henderson, MW., Miller-Awe, M., Abrams, C., Ilich, A., Trebak, F., et al. (2023) 'Factor XII contributes to thrombotic complications and vaso-occlusion in sickle cell disease'. Blood, 141 (15). pp. 1871 - 1883. ISSN: 0006-4971 Open Access Link
Ansari, J., Vital, SA., Yadav, S. and Gavins, FNE. (2023) 'Regulating Neutrophil PAD4/NOX-Dependent Cerebrovasular Thromboinflammation'. International Journal of Biological Sciences, 19 (3). pp. 852 - 864. ISSN: 1449-2288 Open Access Link
Gibson, OR., Astin, R., Puthucheary, Z., Preston, S., Yadav, S., Gavins, FNE. and et al. (2023) 'Skeletal muscle angiogenic, regulatory and heat shock protein responses to prolonged passive hyperthermia of the human lower limb'. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 324 (1). pp. R1 - R14. ISSN: 0363-6119 Open Access Link
Gavins, FN., Yadav, S., Ansari, J. and Iffah, R. (2022) 'Promoting the Resolution of Thromboinflammation'. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 36 (S1). ISSN: 0892-6638
Clerbaux, L-A., Amigó, N., Amorim, MJ., Bal-Price, A., Batista Leite, S., Beronius, A., et al. (2022) 'COVID-19 through Adverse Outcome Pathways: Building networks to better understand the disease - 3rd CIAO AOP Design Workshop'. ALTEX : Alternatives to Animal Experimentation, 39 (2). pp. 322 - 335. ISSN: 0946-7785 Open Access Link
Becker, F., Kebschull, L., Rieger, C., Mohr, A., Heitplatz, B., Van Marck, V., et al. (2022) 'Bryostatin-1 Attenuates Ischemia-Elicited Neutrophil Transmigration and Ameliorates Graft Injury after Kidney Transplantation'. Cells, 11 (6). pp. 1 - 19. ISSN: 2073-4409 Open Access Link
Triay, R., Buchhanolla, P., Gaudet, A., Winter, V., Gaudet, A., Riel-Romero, RMS., et al. (2022) 'The Spectrum of Acute Cerebrovascular Disease in Patients with COVID-19'. Biomedicines, 10 (2). pp. 1 - 13. ISSN: 2227-9059 Open Access Link
Triay, R., Ansari, J., Winter, V., Riel-Romero, RMS., Gonzalez-Toledo, E., Gavins, FNE. and et al. (2022) 'The Spectrum of Acute Cerebrovascular Disease in Patients Hospitalized with COVID-19 Diagnosis at OLSU-S'.146th Annual Meeting of the American Neurological Association (ANA). Virtual. 8 - 19 October. Wiley. pp. S58 - S58. ISSN: 0364-5134 Open Access Link
Ansari, J. and Gavins, FNE. (2021) 'Neutrophils and Platelets: Immune Soldiers Fighting Together in Stroke Pathophysiology'. Biomedicines, 9 (12). pp. 1 - 13. ISSN: 2227-9059 Open Access Link
Bazban-Shotorbani, S., Gavins, F., Kant, K., Dufva, M. and Kamaly, N. (2021) 'A Biomicrofluidic Screening Platform for Dysfunctional Endothelium‐Targeted Nanoparticles and Therapeutics'. Advanced NanoBiomed Research, 2 (1). pp. 1 - 13. ISSN: 2699-9307 Open Access Link
Iffah, R. and Gavins, FNE. (2021) 'Thromboinflammation in coronavirus disease 2019: The clot thickens'. British Journal of Pharmacology, 179 (10). pp. 2100 - 2107. ISSN: 0007-1188 Open Access Link
Boltersdorf, T., Gavins, FNE. and Long, NJ. (2021) 'Long-lived lanthanide emission via a pH-sensitive and switchable LRET complex'. Chemical Science, 12 (25). pp. 1 - 5. ISSN: 2041-6520 Open Access Link
Ansari, J., Gaudet, A., Hicks, J., Stevens, A., Gonzalez-Toledo, E., Riel-Romero, RM., et al. (2021) 'Neurological Manifestations of Patients Hospitalized with COVID-19 Diagnosis at OLSU-S'. Neurology. pp. 3 - 3. ISSN: 0028-3878
Ansari, J. and Gavins, FNE. (2021) 'The Impact of Thrombo‐inflammation on the Cerebral Microcirculation'. Microcirculation, 28 (3). pp. 1 - 11. ISSN: 1073-9688 Open Access Link
Ansari, J., Senchenkova, EY., Vital, SA., Al-Yafeai, Z., Kaur, G., Sparkenbaugh, E., et al. (2021) 'Targeting AnxA1/Fpr2/ALX Regulates Neutrophil Function Promoting Thrombo-Inflammation Resolution in Sickle Cell Disease'. Blood, 137 (11). pp. 1538 - 1549. ISSN: 0006-4971 Open Access Link
Ansari, J., Vital, S., Esen, E. and Gavins, F. (2020) 'Targeting Peptidyl Arginine Deiminase 4 and NADPH Oxidase Pathways Regulates Neutrophil Dependent Thrombo-inflammation'.Pharmacology 2020.. Online. 13 - 18 December. Wiley. pp. 409 - 410. ISSN: 0007-1188
Vital, SA., Senchenkova, EY., Ansari, J. and Gavins, FNE. (2020) 'Targeting AnxA1/Formyl Peptide Receptor 2 Pathway Affords Protection against Pathological Thrombo-Inflammation'. Cells, 9 (11). pp. 1 - 18. ISSN: 2073-4409 Open Access Link
Morse, SV., Boltersdorf, T., Chan, TG., Gavins, FNE., Choi, JJ. and Long, NJ. (2020) 'In vivo delivery of a fluorescent FPR2/ALX-targeted probe using focused ultrasound and microbubbles to image activated microglia'. RSC Chemical Biology, 1 (5). pp. 385 - 389. ISSN: 2633-0679 Open Access Link
Omura, S., Sato, F., Park, A-M., Fujita, M., Khadka, S., Nakamura, Y., et al. (2020) 'Bioinformatics Analysis of Gut Microbiota and CNS Transcriptome in Virus-Induced Acute Myelitis and Chronic Inflammatory Demyelination; Potential Association of Distinct Bacteria with CNS IgA upregulation'. Frontiers in Immunology Mucosal Immunity, 11. pp. 1 - 18. ISSN: 1664-3224 Open Access Link
Boltersdorf, T., Ansari, J., Senchenkova, EY., Groeper, J., Pajonczyk, D., Vital, SA., et al. (2020) 'Targeting of Formyl Peptide Receptor 2 for in vivo imaging of acute vascular inflammation'. Theranostics, 10 (15). pp. 6599 - 6614. ISSN: 1838-7640 Open Access Link
Boltersdorf, T., Ansari, J., Senchenkova, E., Jiang, L., White, AJP., Coogan, M., et al. (2019) 'Development, characterisation and in vitro evaluation of lanthanide-based FPR2/ALX-targeted imaging probes'. Dalton Transactions, 48 (44). pp. 16764 - 16775. ISSN: 1477-9226 Open Access Link
Becker, F., Romero, E., Goetzmann, J., Hasselschwert, DL., Dray, B., Vanchiere, J., et al. (2019) 'Endogenous Specialized Proresolving Mediator Profiles in a Novel Experimental Model of Lymphatic Obstruction and Intestinal Inflammation in African Green Monkeys'. American Journal of Pathology, 189 (10). pp. 1953 - 1972. ISSN: 0002-9440
Senchenkova, EY., Ansari, J., Becker, F., Vital, SA., Al-Yafeai, Z., Sparkenbaugh, EM., et al. (2019) 'Novel Role for the AnxA1-Fpr2/ALX Signaling Axis as a Key Regulator of Platelet Function to Promote Resolution of Inflammation'. Circulation, 140 (4). pp. 319 - 335. ISSN: 0009-7322 Open Access Link
Becker, F., Gavins, FNE., Fontenot, J., Jordan, P., Yun, JY., Scott, R., et al. (2019) 'Dynamic gut microbiome changes following regional intestinal lymphatic obstruction in primates'. Pathophysiology, 26 (3-4). pp. 253 - 261. ISSN: 0928-4680 Open Access Link
Ansari, J. and Gavins, FNE. (2019) 'Ischemia-Reperfusion Injury in Sickle Cell Disease: From Basics to Therapeutics'. The American Journal of Pathology, 189 (4). pp. 706 - 718. ISSN: 0002-9440 Open Access Link
Barzegar, M., Kaur, G., Gavins, FNE., Wang, Y., Boyer, CJ. and Alexander, JS. (2019) 'Potential therapeutic roles of stem cells in ischemia-reperfusion injury'. Stem Cell Research, 37. pp. 1 - 15. ISSN: 1873-5061 Open Access Link
Senchenkova, EY., Russell, J., Yildirim, A., Granger, DN. and Gavins, FNE. (2019) 'Novel Role of T Cells and IL-6 (Interleukin-6) in Angiotensin II–Induced Microvascular Dysfunction'. Hypertension, 73 (4). pp. 829 - 838. ISSN: 0194-911X Open Access Link
Winny Yun, J., Steve Alexander, J. and Gavins, FNE. (2019) 'CNS lymphatics in health and disease', inLymphatic Structure and Function in Health and Disease. Elsevier. pp. 93 - 107. ISBN 13: 9780128156452.
Gavins, FNE. and Steve Alexander, J. (2019) 'Introduction/overview', inLymphatic Structure and Function in Health and Disease. Elsevier. pp. 1 - 4. ISBN 13: 9780128156452.
Gavins, FNE. and Steve Alexander, J. (2019) 'Lymphatic structure and function in health and disease'. Elsevier. ISSN 13: 9780128156452
Al-Kofahi, M., Omura, S., Tsunoda, I., Sato, F., Becker, F., Gavins, FNE., et al. (2018) 'IL-1β reduces cardiac lymphatic muscle contraction via COX-2 and PGE2 induction: Potential role in myocarditis'. Biomedicine & Pharmacotherapy, 107 (November 2018). pp. 1591 - 1600. ISSN: 0753-3322
Gillespie, S., Holloway, PM., Becker, F., Rauzi, F., Vital, SA., Taylor, KA., et al. (2018) 'The isothiocyanate sulforaphane modulates platelet function and protects against cerebral thrombotic dysfunction'. British Journal of Pharmacology, 175 (16). pp. 3333 - 3346. ISSN: 0007-1188
Senchenkova, EY., Russell, J., Vital, SA., Yildirim, A., Orr, AW., Granger, DN. and et al. (2018) 'A critical role for both CD40 and VLA5 in angiotensin II–mediated thrombosis and inflammation'. The FASEB Journal, 32 (6). pp. 3448 - 3456. ISSN: 0892-6638 Open Access Link
Smith, HK., Omura, S., Vital, SA., Becker, F., Senchenkova, EY., Kaur, G., et al. (2018) 'Metallothionein I as a direct link between therapeutic hematopoietic stem/progenitor cells and cerebral protection in stroke'. The FASEB Journal, 32 (5). pp. 2381 - 2394. ISSN: 0892-6638 Open Access Link
Ansari, J., Kaur, G. and Gavins, F. (2018) 'Therapeutic Potential of Annexin A1 in Ischemia Reperfusion Injury'. International Journal of Molecular Sciences, 19 (4). pp. 1 - 19. ISSN: 1661-6596 Open Access Link
Ansari, J., Moufarrej, YE., Pawlinski, R. and Gavins, FNE. (2018) 'Sickle cell disease: a malady beyond a hemoglobin defect in cerebrovascular disease'. Expert Review of Hematology, 11 (1). pp. 45 - 55. ISSN: 1747-4086
Igbinedion, SO., Ansari, J., Vasikaran, A., Gavins, F., Jordan, P., Boktor, M. and et al. (2017) 'Non-celiac gluten sensitivity: All wheat attack is not celiac'. World Journal of Gastroenterology, 23 (40). pp. 7201 - 7210. ISSN: 1007-9327 Open Access Link
Hughes, EL., Becker, F., Flower, RJ., Buckingham, JC. and Gavins, FNE. (2017)
'Mast cells mediate early neutrophil recruitment and exhibit anti-inflammatory properties via the formyl peptide receptor 2/lipoxin A
Becker, F., Holthoff, C., Anthoni, C., Rijcken, E., Alexander, JS., Gavins, FNE., et al. (2016) 'Downregulation of CX3CR1 ameliorates experimental colitis: evidence for CX3CL1-CX3CR1-mediated immune cell recruitment'. International Journal of Colorectal Disease, 32 (3). pp. 315 - 324. ISSN: 0179-1958
Vital, SA. and Gavins, FNE. (2016) 'Surgical Approach for Middle Cerebral Artery Occlusion and Reperfusion Induced Stroke in Mice'. Journal of Visualized Experiments, 2016 (116). ISSN: 1940-087X
Holloway, PM., Gillespie, S., Becker, F., Vital, SA., Nguyen, V., Alexander, JS., et al. (2016) 'Sulforaphane induces neurovascular protection against a systemic inflammatory challenge via both Nrf2-dependent and independent pathways'. Vascular Pharmacology, 85. pp. 29 - 38. ISSN: 1537-1891 Open Access Link
Becker, F., Kurmaeva, E., Gavins, FNE., Stevenson, EV., Navratil, AR., Jin, L., et al. (2016) 'A Critical Role for Monocytes/Macrophages During Intestinal Inflammation-associated Lymphangiogenesis'. Inflammatory Bowel Diseases, 22 (6). pp. 1326 - 1345. ISSN: 1078-0998
Vital, SA., Becker, F., Holloway, PM., Russell, J., Perretti, M., Granger, DN. and et al. (2016) 'Formyl-Peptide Receptor 2/3/Lipoxin A4 Receptor Regulates Neutrophil-Platelet Aggregation and Attenuates Cerebral Inflammation Impact for Therapy in Cardiovascular Disease'. Circulation, 133 (22). pp. 2169 - 2179. ISSN: 0009-7322 Open Access Link
Holloway, PM. and Gavins, FNE. (2016) 'Modeling Ischemic Stroke in Vitro: Status Quo and Future Perspectives'. Stroke, 47 (2). pp. 561 - 569. ISSN: 0039-2499
Gavins, FNE. and Stokes, KY. (2016) 'Overview'. Elsevier. ISSN 13: 9780128010785
Gavins, FNE. (2016) 'Sepsis', inVascular Responses to Pathogens. Elsevier. pp. 1 - 9. ISBN 13: 9780128010785.
Gavins, FNE. and Stokes, KY. (2015) 'Vascular Responses to Pathogens'. Elsevier. ISSN 13: 9780128010785
Al-Kofahi, M., Becker, F., Gavins, FNE., Woolard, MD., Tsunoda, I., Wang, Y., et al. (2015)
'IL-1β reduces tonic contraction of mesenteric lymphatic muscle cells, with the involvement of cycloxygenase-2 and prostaglandin E