Skip to main content

Impact case studies

Case studies of impact from the Centre for Inflammation Research and Translational Medicine (CIRTM) 

Read our publications 

2023

  1. Sparkenbaugh EM, Henderson MW, Miller-Awe MD, Abrams C, Ilich A, Trebak F, et al. (2023). ‘Factor XII contributes to thrombotic complications and vaso-occlusion in sickle cell disease.’ Blood ISSN: 1528-0020.

  2. Ansari, J., Vital, S. A., Yadav, S. and Gavins, F. N. E., (2023). ‘Regulating Neutrophil PAD4/NOX-Dependent Cerebrovasular Thromboinflammation’. International Journal of Biological Sciences 19 (3), pp. 852–864.  ISSN: 1449-2288.

  3. Gibson, O. R., Astin, R., Puthucheary, Z., Yadav, S., Preston, S., Gavins, F. N. E., et al. (2023) ‘Skeletal muscle angiogenic, regulatory and heat shock protein responses to prolonged passive hyperthermia of the human lower limb’. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 324(1) ISSN: 1522-1490.

  4. Bah, S. Y., Keeley, A. J., Armitage, E. P. Khalid, H., Chaudhuri R. R., Senghore, E., et al.  (2023). ‘Genomic Characterization of Skin and Soft Tissue Streptococcus pyogenes Isolates from a Low-Income and a High-Income Setting’. mSphere 8(1) ISSN: 2379-5042.

  5. Bland, V. L., Bea, J. W., Going, S. B., Yaghootkar, H., Arora, A., Ramadan, F., et al. (2023). ‘Metabolically favorable adiposity and bone mineral density: a Mendelian randomization analysis’. Obesity 31(1) pp. 267-278 ISSN: 1930-739X.

  6. Kadeřábková N, Furniss RCD, Maslova E, Eisaiankhongi L, Bernal P, Filloux A, Landeta C, Gonzalez D, McCarthy RR, Mavridou DAI. Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis. bioRxiv [Preprint]. 2023.

  7. Maslova E, Osman S, McCarthy RR. Using the Galleria mellonella burn wound and infection model to identify and characterize potential wound probiotics. Microbiology (Reading). 2023;169:001350.

  8. Kim H, Proctor CR, Walker D, McCarthy RR. Understanding the Consumption of Antimicrobial Resistance-Related Content on Social Media: Twitter Analysis. J Med Internet Res. 2023;25:e42363.

  9. Proctor CR, Taggart MG, O'Hagan BMG, McCarron PA, McCarthy RR, Ternan NG. Furanone loaded aerogels are effective antibiofilm therapeutics in a model of chronic Pseudomonas aeruginosa wound infection. Biofilm. 2023.

  10. De Dios R, Proctor CR, Maslova E, Dzalbe S, Rudolph CJ, McCarthy RR. Artificial sweeteners inhibit multidrug-resistant pathogen growth and potentiate antibiotic activity. EMBO Mol Med. 2023;15:e16397.

  11. de Dios R, Gadar K, McCarthy RR. A high-efficiency scar-free genome-editing toolkit for Acinetobacter baumannii. J Antimicrob Chemother. 2022;77:3390-3398.

  12. Hezekiah, C., Blakemore, A., Bailey, D. & Pazoki, R. Physical activity reduces the effect of adiposity genetic liability on hypertension risk in the UK Biobank cohort. medRxiv, 2023.

  13. C. Eckold, C. L. R. van Doorn, R. Ruslami, K. Ronacher, A. L. Riza, S. van Veen, J.-S. Lee, V. Kumar, S. Kerry-Barnard, S. Malherbe, L. Kleynhans, K. Stanley, S. A. Joosten, J. A. Critchley, P. C. Hill, R. van Crevel, C. Wijmenga, M. Haks, M. Ioana, B. Alisjahbana, G. Walzl, T. H. M. Ottenhoff, H. M. Dockrell, E. Vianello and J. M. Cliff: Impaired resolution of blood transcriptomes through tuberculosis treatment with diabetes comorbidity. Clinical and Translational Medicine, 2023;13:e1375.

  14. T. D. Domingues, J. Malato, A. D. Grabowska, J. S. Lee, J. Ameijeiras-Alonso, P. Biecek, L. Graca, H. Mourino, C. Scheibenbogen, F. Westermeier, L. Nacul, J. M. Cliff, E. Lacerda and N. Sepulveda: Association analysis between symptomology and herpesvirus IgG antibody concentrations in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple sclerosis. Heliyon. 2023;9:e18250. 

2022

  1. Iffah, Raayma, and Felicity N. E. Gavins. (2022) ‘Thromboinflammation in COVID‐19: The Clot Thickens’. British Journal of Pharmacology ISSN:1476-5381. 

  2. Becker, F., Kebschull, L., Rieger, C., Mohr, A., Heitplatz, B., Van Marck, V., et al. (2022). ‘Bryostatin-1 Attenuates Ischemia-Elicited Neutrophil Transmigration and Ameliorates Graft Injury after Kidney Transplantation’. Cells 11(6), pp. 948 ISSN: 2073-4409. 

  3. Ragusa, D., Cicirò, Y., Federico, C., Saccone, S., Bruno, F., Saeedi, R., et al. (2022). ‘Engineered model of t(7;12)(q36;p13) AML recapitulates patient-specific features and gene expression profiles’. Oncogenesis 11(1) pp. 50 ISSN: 2157-9024.
     
  4. Triay, R., Buchhanolla, P., Gaudet, A., Winter, V., Gaudet, A., Faraji, M., et al. (2022). ‘The Spectrum of Acute Cerebrovascular Disease in Patients with COVID-19’. Biomedicines 10(2), pp. 435. ISSN 2227-9059.

  5. Clerbaux, L.-A., et al., (2022). ‘COVID-19 through Adverse Outcome Pathways: Building networks to better understand the disease – 3rd CIAO AOP Design Workshop’. ALTEX 39(2), pp. 322–335 ISSN: 1868-596X.

  6. O'Boyle, S., Nacul, L., Nacul, F. E., Mudie, K., Kingdon, C. C., Cliff, J. M., et al. (2022). ‘A Natural History of Disease Framework for Improving the Prevention, Management, and Research on Post-viral Fatigue Syndrome and Other Forms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome’. Frontiers in Medicine 8. ISSN: 2296-858X.

  7. Symonds, A. L. J., Miao, T., Busharat, Z., Li, S., and Wang, P., (2022). ‘Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells’. Cancer Immunology, Immunotherapy ISSN: 1432-0851.

  8. Roa-Díaz, Z. M., Teuscher, J., Gamba, M., Bundo, M., Grisotto, G., Wehrli, F., et al. (2022). ‘Gene-diet interactions and cardiovascular diseases: a systematic review of observational and clinical trials’. BMC cardiovascular disorders, 22(1), pp. 377 ISSN: 1471-2261.

  9. O'Farrell, F., Jiang, X., Aljifri, S., and Pazoki, R. (2022). ‘Molecular Alterations Caused by Alcohol Consumption in the UK Biobank: A Mendelian Randomisation Study’. Nutrients, 14(14), 2943. ISSN: 2072-6643.

  10. Jiang, X., Anasanti, M. D., Drenos, F., Blakemore, A. I., and Pazoki, R. (2022). ‘Urinary Sodium Excretion Enhances the Effect of Alcohol on Blood Pressure’. Healthcare (Basel, Switzerland), 10(7), pp1296. ISSN: 2227-9032.

  11. Said, S., Pazoki, R., Karhunen, V., Võsa, U., Ligthart, S., Bodinier, B., et al. (2022). ‘Author Correction: Genetic analysis of over half a million people characterises C-reactive protein loci’. Nature Communications, 13(1), pp. 3865. ISSN: 2041-1723.

  12. Ahmed, A., Sattar, N. and Yaghootkar, H., (2022). ‘Advancing a causal role of type 2 diabetes and its components in developing macro and microvascular complications via genetic studies’. Diabetic Medicine 39(12) ISSN: 1464-5491.

  13. Thompson, W. D., Beaumont, R. N., Kuang, A., Warrington, N. M., Ji, Y., Tyrrell, J., et al. (2022). ‘Fetal alleles predisposing to metabolically favorable adiposity are associated with higher birth weight’. Human Molecular Genetics 31(11) pp. 1762-1775 ISSN: 1460-2083.

  14. Seidelin, A. S., Nordestgaard, B. G., Tybjaerg-Hansen, A., Yaghootkar, H. and Stender, S., (2022). ‘A rare genetic variant in the manganese transporter SLC30A10 and elevated liver enzymes in the general population’. Atherosclerosis 16(3) pp. 702-711 ISSN: 0021-9150.

  15. Martin, S., Tyrrell, J., Thomas E. L., Bown, M. J., Wood, A. R., Beaumont R. N., et al. (2022) ‘Correction: Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation’. eLife 11 ISSN: 2050-084X.

  16. Razzaghy-Azar, M., Saeedi, S., Dayani, S. B., Enayati, S., Abbasi, F., Hashemian, S., Eshraghi, P., et al. (2022). ‘Investigating Genetic Mutations in a Large Cohort of Iranian Patients with Congenital Hyperinsulinism’. Journal of Clinical Research in Pediatric Endocrinology  14(1) pp. 87-95 ISSN: 1308-5735.

  17. Martin, S., Sorokin, E. P., Thomas, E. L., Sattar, N., Cule, M., Bell, J. D. and Yaghootkar, H., (2022). ‘Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study’. Diabetes Care 45(2) pp. 460-468 ISSN: 0149-5992.

  18. Gevaert, P., Han, J. K., Smith, S. G., Sousa, A. R., Howarth, P. H., Yancey, S. W., et al. (2022). ‘The roles of eosinophils and interleukin‐5 in the pathophysiology of chronic rhinosinusitis with nasal polyps’. International Forum of Allergy & Rhinology 12(11) pp. 1413-1423 ISSN: 2042-6984.

  19. Israel, E., Canonica, G. W., Brusselle, G., Yang, S., Howarth, P. H., Martin, A. L., et al. (2022). ‘Real-life effectiveness of mepolizumab in severe asthma: a systematic literature review’. Journal of Asthma 59(11) pp. 2201-2217 ISSN: 1532-4303.

  20. Borish, L., Cohen, N. A., Chupp, G., Hopkins, C., Wagenmann, M., Sousa, A. R., et al. (2022). ‘Evaluating enrolment and outcome criteria in trials of biologics for chronic rhinosinusitis with nasal polyps’. Annals of Allergy, Asthma & Immunology 129(2) pp. 160-168 ISSN: 1081-1206.
     
  21. Pérez-Hernández, C. A., Moreno-Altamirano, M. M. B., López-Villegas, E. O., Butkeviciute, E., Ali, M., Kronsteiner, B., et al. (2022). ‘Mitochondrial Ultrastructure and Activity Are Differentially Regulated by Glycolysis-, Krebs Cycle-, and Microbiota-Derived Metabolites in Monocytes’. Biology 11(8), pp. 1132. ISSN: 2079-7737.

  22. Bachert, C., Sousa, A. R., Han, J. K., Schlosser, R. J., Sowerby, L. J., Hopkins, C., et al. (2022). ‘Mepolizumab for chronic rhinosinusitis with nasal polyps: Treatment efficacy by comorbidity and blood eosinophil count’. Journal of Allergy and Clinical Immunology 149(5) pp. 1711-1721 ISSN: 0091-6749.

  23. Korn, S., Howarth, P., Smith, S. G., Price, R. G., Yancey, S. W., Prazma, C. M. and Bel, E. H., (2022). ‘Development of methodology for assessing steroid-tapering in clinical trials for biologics in asthma’. Respiratory Research 23(1). pp. 45 ISSN: 1465-993X.

  24. Liu, M. C., Bel, E. H., Kornmann, O., Moore, W. C., Kaneko, N., Smith, S. G et al. (2022). ‘Health outcomes after stopping long-term mepolizumab in severe eosinophilic asthma: COMET’. ERJ Open Research 8(1) pp. 419-2021 ISSN: 2312-0541.

  25. Moore, W. C., Kornmann, O., Humbert, M., Poirier, C., Bel, E. H., Kaneko, N., et al. (2022). ‘Stopping versus continuing long-term mepolizumab treatment in severe eosinophilic asthma (COMET study)’. European Respiratory Journal 59(1) pp. 2100396 ISSN: 1399-3003.

  26. Bitencourt, J., Peralta-Álvarez, M. P., Wilkie, M., Jacobs, A., Wright, D., Salman Almujri, S., et al. (2022). ‘Induction of Functional Specific Antibodies, IgG-Secreting Plasmablasts and Memory B Cells Following BCG Vaccination’. Frontiers in Immunology 12:798207 ISSN: 1664-3224.

  27. Jagne, I., Keeley, A. J., Bojang, A., Camara, B., Jallow, E., Senghore, E., et al. (2022). ‘Impact of intra-partum azithromycin on carriage of group A streptococcus in the Gambia: a posthoc analysis of a double-blind randomized placebo-controlled trial’. BMC Infectious Diseases 22(1) pp. 103 ISSN: 1471-2334.

  28. Turner, C. E., (2022). ‘Can group A streptococcus infections be influenced by viruses in the respiratory tract?’ The Lancet Infectious Diseases 23(2) pp. 142-144 ISSN: 1473-3099.
     
  29. Boulind, C. E., Gould, O., de Lacy Costello, B., Allison, J., White, P., Ewings, P., et al. (2022). ‘Urinary Volatile Organic Compound Testing in Fast-Track Patients with Suspected Colorectal Cancer’. Cancers 14(9) pp. 2127 ISSN: 2072-6694.

2021

  1. Agostinis, C., Balduit, A., Mangogna, A., Zito, G., Romano, F., Ricci, G., et al. (2021) ‘Immunological Basis of the Endometriosis: The Complement System as a Potential Therapeutic Target’. Frontiers in Immunology, 11. pp. 599117. ISSN: 1664-3224.

  2. Agostinis, C., Zorzet, S., Balduit, A., Zito, G., Mangogna, A., Macor, P., et al. (2021) ‘The inflammatory Feed-Forward Loop Triggered by the Complement Component C3 as a Potential Target in Endometriosis’. Frontiers in immunology, 12. ISSN: 1664-3224.

  3. Ansari, J., Gavins, F.,(2021) ‘The Impact of Thrombo-inflammation on the Cerebral Microcirculation. Microcirculation.’ Microcirculation., 10 (15). pp.6599 - 6614. ISSN:1838-7640.

  4. Ansari, J., Senchenkova, EY., Vital, SA., Al-Yafeai, Z., Kaur, G., Sparkenbaugh EM., et al.(2021) ‘Targeting the AnA1/Fpr2/ALX pathway regulates neutrophil function, promoting thromboinflammation resolution in sickle cell disease.’ Blood., 137 (13). pp.1538 - 1549. ISSN: 0006-4971.

  5. Awoyemi, T., Motta-Mejia, C., Zhang, W., Kouser, L., White, K., Kandzija, N., et al. (2021) ‘Syncytiotrophoblast Extracellular Vesicles From Late-Onset Preeclampsia Placentae Suppress Pro-Inflammatory Immune Response in THP-1 Macrophages’. Frontiers in immunology, 12. pp. 676056. ISSN: 1664-3224.

  6. Bazban-Shotorbani, S.,  Gavins, F., Kant, K., Dufva, M., Kamaly, N., (2021) ‘A biomicrofluidic screening platform for dysfunctional endothelium targeted nanoparticles and therapeutics.’ BioRXiv. May 2021, doi: https://doi.org/10.1101/2021.05.09.443301.

  7. Boltersdorf, T., Gavins, F., Long, NJ., (2021) ‘Long-lived lanthanide emission via a pH-sensitive and switchable LRET complex’. Chemical Science., 12 (25). pp. 8740 - 8745. ISSN: 2041-6520.

  8. Cicirò, Y., Sala, A., (2021) ‘MYB oncoproteins: emerging players and potential therapeutic targets in human cancer’. Oncogenesis, 10 (2). pp. 19. ISSN: 2157-9024.

  9. Evangelou, E., Suzuki, H., Bai, W., Pazoki, R., Goa, H., Matthews, PM., et al. (2021) ‘Alcohol consumption in the general population is associated with structural changes in multiple organ systems’. eLife, 10. ISSN: 2050-084X.

  10. Ferluga, J., Singh, I., Rout, S., Al-Qahtani, A., Yasmin, H., Kishore, U., (2021) ‘Immune Responses in Malaria and Vaccine Strategies’. Advances in experimental medicine and biology, 1313. pp. 273-291. ISSN: 0065-2598.

  11. Ferluga, J., Yasmin, H., Bhakta, S., Kishore, U., (2021) ‘Vaccination Strategies Against Mycobacterium tuberculosis: BCG and Beyond’. Advances in experimental medicine and biology, 1313. pp. 217 - 240. ISSN:0065-2598.

  12. Ganguly, K., Kishore, U., Madan, T., (2021) ‘ Interplay between C-type lectin receptors and microRNAs in cellular homeostasis and immune response’. The FEBS journal, 288 (14). pp. 4210 - 4229. ISSN: 1742-464X.

  13. Houlden, A., and MacKay, R., (2021), ‘Can microfluidics be used to create a more realistic in vitro model of the vaginal ectocervix to better understand bacterial vaginosis?’ Sexually Transmitted Infections, ISSN: 1368-4973.

  14. Hsieh, MH., Beirag, N., Murugaiah, V., Chou, YC., Kuo, WS., Koa, HF., et al. (2021) ‘Human Surfactant Protein D Binds Spike Protein and Acts as an Entry Inhibitor of SARS-CoV-2 Pseudotyped Viral Particles’. Frontiers in immunology, 12. pp. 641360. ISSN: 1664-3224.

  15. Iffah, R., Gavins, F., (2021) ‘Thromboinflammation in coronavirus disease 2019: The Clot Thickens’. Br J British Journal of pharmacology., ISSN: 0007-1188.

  16. Jagatia, H., Tsolaki, AG., (2021) ‘ The role of complement system and the immune response to tuberculosis infection’ Medicina, 57 (2). pp. 1 - 18. ISSN: 1010-660X, 1648-9144.

  17. Katopodis, P., Anikin, V., Kishore, U., Carter, T., Hall, M., Asadi, N., et al. (2021) ‘ Circulating tumour cells and circulating cell-free DNA in patients with lung cancer: a comparison between thoracotomy and video-assisted thoracoscopic surgery’. BMJ open respiratory research, 8 (1). pp. e000917. ISSN: 2052-4439.

  18. Khan, HA., Kishore, U., Alsulami, HM., Alrokayan, SH., (2021) ‘Pro-apoptotic and immunotherapeutic effects of carbon nanotubes functionalized with recombinant human surfactant protein d on leukemic cells’. International journal of molecular sciences, 22 (19). pp. 10445. ISSN: 1661-6596, 1422-0067.

  19. Kishore, U., (2021) ‘Preface’. Advances in experimental medicine and biology, 1313. pp. ix- x. ISSN: 0065-2598.

  20. Madan, T., Biswas, B., Varghese, M., Subedi, R., Pandit, H., Idicula-Thomas, S., et al. (2021) ‘A Recombinant Fragment of Human Surfactant Protein D Binds Spike Protein and Inhibits Infectivity and Replication of SARS-CoV-2 in Clinical Samples’. American journal of respiratory cell and molecular biology, 65 (1). pp. 41-53. ISSN: 1044-1549.

  21. Mangogna, A., Varghese, PM., Agostinis, C., Alrokayan, SH., Khan, HA., Stover, CM., (2021) ‘Prognostic Value of Complement Properdin in Cancer’. Frontiers in immunology, 11. pp. 614980. ISSN: 1664-3224.

  22. Marmon, P., Owen, SF., Margiotta-Casaluci, L., (2021) ‘Pharmacology-informed prediction of the risk posed to fish by mixtures of non-steroidal anti-inflammatory drugs (NSAIDs) in the environment’. Environment international, 146. pp. 106222 ISSN: 0160-41202020.

  23. Maslova, E., Eisaiankhongi, L., Sjöberg, F.,  McCarthy RR., (2021) ‘Burns and biofilms: priority pathogens and in vivo models’. NPJ biofilms and microbiomes, 7 (1). pp. 73. ISSN: 2055-5008.

  24. Mawa, PA., Hasso-Agopsowicz, M., Lubyayi, L., Nabakooza, G., Nakibuule, M., Blitz, R., et al. (2021) ‘Immune Responses Following BCG Immunization of Infants in Uganda and United Kingdom Are Similar for Purified Protein Derivative but Differ for Secretory Proteins’ Frontiers in Immunology, 12. pp. 637114. ISSN: 1664-3224.

  25. McCarthy, RR., Larrouy-Maumus, GJ., Meiqi Tan, MGC., Wareham, DW., (2021) ‘Antibiotic Resistance Mechanisms and Their Transmission in Acinetobacter baumannii’. Advances in experimental medicine and biology, 1313. pp. 135 -153. ISSN: 0065-2598.

  26. McCleary, S., McCarthy, RR., Strong, R., Edwards, J., Crooke, H., (2021) ‘Inactivation of African Swine Fever Virus by reagents commonly used in containment laboratories’. Journal of virological methods, 295. pp. 114203. ISSN: 0166-0934.

  27. Murugaiah, V., Yasmin, H., Pandit, H., Ganguly, K., Subedi, R., Al-Mozaini, M., et al. (2021) ‘Innate Immune Response Against HIV-1’. Advances in experimental medicine and biology, 1313. pp. 23- 58. ISSN: 0065-2598.

  28. Pazoki, R., Lin, BD., van Eijk, KR., Schijven, D., de Zwarte, S., Guloksuz, S., et al. (2021) ‘Phenome-wide and genome-wide analyses of quality of life in schizophrenia (vol 7, e13, 2021)’. BJPsych open, 7 (2). pp. 1. ISSN: 2056-4724, 2056-4724.

  29. Pazoki, R., Vujkovic, M., Elliott, J., Evangelou, E., Gill, D., Ghanbari, M., et al. (2021) ‘Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes’. Nature communications, 12 (1). ISSN: 2041-1723, 2041-1723.

  30. Rehman, S., Ravinayagam, V., Nahvi, I., Aldossary, H., Al-Shammari, M., Amiri, MSA., et al. (2021) ‘Immunity, Sex Hormones, and Environmental Factors as Determinants of COVID-19 Disparity in Women’. Frontiers in immunology, 12. pp. 680845. ISSN: 1664-3224.

  31. Remmington, A., Haywood, S., Edgar, J., Green, LR., de Silva, T., Turner, CE., (2021) ‘Cryptic prophages within a streptococcus pyogenes genotype EMM4 lineage’. Microbial genomics, 7 (1). pp. 1 - 14. ISSN: 2057-5858.

  32. Roa-Díaz, ZM., Asllanaj, E., Amin, HA., Rojas, LZ., Nano, J., Ikram, MA., et al. (2021) ‘Age at natural menopause and blood pressure traits: Mendelian randomization study’. Journal of clinical medicine,  10 (19). pp. 4299. ISSN: 2077-0383.

  33. Sánchez-Cordón, PJ., Floyd, T., Hicks, D., Crooke, HR., McCleary, S., McCarthy, RR., et al. (2021) ‘Evaluation of Lesions and Viral Antigen Distribution in Domestic Pigs Inoculated Intranasally with African Swine Fever Virus Ken05/Tk1 (Genotype X)’. Pathogens (Basel), 10 (6). pp. 768. ISSN: 2076-0817.

  34. Tagalakis, AD., Jayarajan, V., Maeshima, R., Ho, KH., Syed, F., Wu, L., et al. (2021) ‘Integrin- Targeted, Short Interfering RNA Nanocomplexes for Neuroblastoma Tumor-Specific Delivery Achieve MYCN Silencing with Improved Survival’. Advanced functional materials, 31(37). pp. 2104843 - n/a. ISSN: 1616-301X.

  35. Tan, LKK., Reglinski, M., Teo, D., Reza, N., Lamb, LEM., Nageshwaran, V., et al. (2021) ‘Vaccine-induce, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease’. Npj vaccines, 6 (1). pp. 62. ISSN: 2059-0105.

  36. Tsolaki, AG., Varghese, PM., Kishore, U., (2021) ‘Innate Immune Pattern Recognition Receptors of Mycobacterium tuberculosis: Nature and Consequences for Pathogenesis of Tuberculosis’ Advances in experimental medicine and biology, 1313. pp. 179 - 215. ISSN: 0065-2598.

  37. Ullah, MW., Rojas, OJ., McCarthy, RR., Yang, G., (2021) ‘Editorial: Nanocellulose: A Multipurpose Advanced Functional Material’. Frontiers in bioengineering and biotechnology, 9. pp. 738779. ISSN: 2296-4185.

  38. Varghese, PM., Murugaiah, V., Beirag, N., Temperton, N., Khan, HA., Alrokayan, SH., et al. (2021) ‘C4b Binding Protein Acts as an Innate Immune Effector Against Influenza A Virus’. Frontiers in immunology, 11. pp. 585361. ISSN: 1664-3224.

  39. Yasmin, H., Saha, S., Butt, MT., Modi, RK., George, AJT., Kishore, U., (2021) ‘SARS-CoV-2: Pathogenic Mechanisms and Host Immune Response’. Advances in experimental medicine and biology, 1313. pp. 99 - 134. ISSN: 0065-2598.

  40. Yasmin, H., Varghese, PM., Bhakta, S., Kishore, U., (2021) ‘ Pathogenesis and Host Immune Response in Leprosy’. Advances in experimental medicine and biology, 1313. pp. 155-177. ISSN: 0065-2598.

  41. Ansari, Junaid, and Felicity N. E. Gavins. (2021). ‘Neutrophils and Platelets: Immune Soldiers Fighting Together in Stroke Pathophysiology’. Biomedicines 9(12), pp. 1945 ISSN: 2227-9059.

  42. Cilliers, K., Menezes, A., Webber, T., Dockrell, H. M., Cliff, J. M., Kleynhans, L., et al. (2021). ‘Mycobacterium tuberculosis-stimulated whole blood culture to detect host biosignatures for tuberculosis treatment response’. Tuberculosis 128. pp. 102082. ISSN: 1472-9792.

  43. Broderick, C., Cliff, J. M., Lee, J.-S., Kaforou, M., and Moore, D. A. (2021). ‘Host transcriptional response to TB preventive therapy differentiates two sub-groups of IGRA-positive individuals’. Tuberculosis pp. 102033. ISSN: 1472-9792.

  44. Roa-Díaz, Z. M., Asllanaj, E., Amin, H. A., Rojas, L. Z., Nano, J., Ikram, M. A., et al. (2021). ‘Age at Natural Menopause and Blood Pressure Traits: Mendelian Randomization Study’. Journal of Clinical Medicine, 10(19), pp. 4299. ISSN: 2077-0383.

  45. Evangelou, E., Suzuki, H., Bai, W., Pazoki, R., Gao, H., Matthews, P. M., and Elliott, P. (2021). ‘Alcohol consumption in the general population is associated with structural changes in multiple organ systems’. eLife, 7(2) pp. 10, ISSN: 2056-4724.

  46. Tsakaneli, A., Carregari, V. C., Morini, M., Eva, A., Cangemi, G., Chayka, O., et al. (2021). ‘MYC regulates metabolism through vesicular transfer of glycolytic kinases’. Open Biology 11(12). pp. 210276. ISSN: 2046-2441.

  47. Tagalakis, A. D., Jayarajan, V., Maeshima, R., Ho, K. H., Syed, F., Wu, L., et al. (2021). ‘Integrin‐Targeted, Short Interfering RNA Nanocomplexes for Neuroblastoma Tumor‐Specific Delivery Achieve MYCN Silencing with Improved Survival’. Advanced Functional Materials 31(37), pp. 2104843. ISSN: 1616-3028.
     
  48. Cicirò, Y. and Sala, A., (2021). ‘MYB oncoproteins: emerging players and potential therapeutic targets in human cancer’. Oncogenesis 10(2) pp. 19 ISSN: 2157-9024.

  49. Pazoki, R., Lin, B. D., van Eijk, K. R., Schijven, D., de Zwarte, S., GROUP Investigators, et al., (2021). ‘Phenome-wide and genome-wide analyses of quality of life in schizophrenia – ERRATUM’. BJPsych Open, 7(2), ISSN: 2056-4724.

  50. Pazoki, R. et al., (2021). ‘Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes’. Nature Communications [online]. 12(1) pp. 2579. ISSN: 2041-1723.
     
  51. Simonovich, S. D., Spurlark, R. S., Badowski, D., Krawczyk, S., Soco, C., Ponder, T. N., et al. (2021). ‘Examining effective communication in nursing practice during COVID‐19: A large‐scale qualitative study’. International Nursing Review, 68(4), pp. 512-523 ISSN: 1466-7657.

  52. McCarthy, R. R., Larrouy-Maumus, G. J., Meiqi Tan, M. G. C., and Wareham, D. W. (2021). ‘Antibiotic Resistance Mechanisms and Their Transmission in Acinetobacter baumannii’. Advances in Experimental Medicine and Biology, 1313, pp. 135–153.

  53. Kamble, N., Gurung, A., Kaufer, B. B., Pathan, A. A., and Behboudi, S. (2021). ‘Marek’s Disease Virus Modulates T Cell Proliferation via Activation of Cyclooxygenase 2-Dependent Prostaglandin E2’. Frontiers in Immunology. 12:801781. ISSN: 1664-3224.

  54. Li, S., Li, S., Liu, J., Wang, Z., and Yuan, P., (2021). ‘[Mechanism of Gynostemma pentaphyllum in treatment of metabolism associated fatty liver disease based on network pharmacology and molecular docking]’. Zhongguo Zhong Yao Za Zhi 46(19), pp. 5080-5087.

  55. Han, J. K.  Bachart, C., Fokkens, W., Desrosiers, M., Wagenmann, M., Lee, S.E., et al., (2021). ‘Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial’. The Lancet Respiratory Medicine 9(10) pp. 1141-1153 ISSN: 2213-2600.

  56. Lugogo, N., Liu, M. C., Pavord, I., Mitchell, P. D., Smith, S. G., Mallett, S., et al. (2021). ‘Clinical effects of mepolizumab in patients with severe eosinophilic asthma according to background therapy: A meta-analysis’. The Journal of Allergy and Clinical Immunology: In Practice 9(9), pp. 3506–3509 ISSN:2213-2198.

  57. Lemiere, C., Taille, C., Lee, J. K., Smith, S. G., Mallett, S., Albers, F. C., et al. (2021) ‘Impact of baseline clnical asthma characteristics on the response to mepolizumab: a post hoc meta-analysis of two Phase III trials’. Journal of Allergy and Clinical Immunology 147(2) ISSN: 0091-6749.

  58. Gibson, P. G., Prazma, C. M., Chupp, G. L., Bradford, E. S., Forshag, M., Mallett, S. A., et al. (2021). ‘Mepolizumab improves clinical outcomes in patients with severe asthma and comorbid conditions’. Respiratory Research 22(1) pp. 171. ISSN: 1465-993X.
     
  59. Liu, M. C., Chipps, B., Munoz, X., Devouassoux, G., Bergna, M., Smith, S. G., et al. (2021). ‘Benefit of switching to mepolizumab from omalizumab in severe eosinophilic asthma based on patient characteristics’. Respiratory Research 22(1), pp. 144.
     
  60. Mawa, P. A., Hasso-Agopsowicz, M., Lubyayi, L., Nabakooza, G., Nakibuule, M., Blitz, R., et al. (2021). ‘Immune Responses Following BCG Immunization of Infants in Uganda and United Kingdom Are Similar for Purified Protein Derivative but Differ for Secretory Proteins of Mycobacterium tuberculosis’. Frontiers in Immunology 12. ISSN: 1664-3224.

  61. Pate, L., Desmedt, C., Metzger, O., Burgess Hutcheson, L., Turner, C., Freeney, S. and Oesterreich, S., (2021). ‘How Researchers, Clinicians and Patient Advocates Can Accelerate Lobular Breast Cancer Research’. Cancers 13(13), pp. 3094 ISSN: 2072-6694.

  62. Tan, L. K. K., Reglinski, M., Teo, D., Reza, N., Lamb, L. E. M., Nageshwaran, V., et al. (2021). ‘Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease’. NPJ Vaccines 6(1) pp. 62 ISSN: 2059-0105.

  63. Remmington, A., Haywood, S., Edgar, J., Green, L. R., de Silva, T. and Turner, C. E., (2021). ‘Cryptic prophages within a Streptococcus pyogenes genotype emm4 lineage’. Microbial Genomics 7(1) ISSN: 2057-5858.

  64. Thompson, W. D., Beaumont, R. N., Kuang, A., Warrington, N. M., Ji, Y., Tyrrell, J., et al. (2021). ‘Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile’. Diabetologia 64(12) pp. 2790-2802 ISSN: 1432-0428.

  65. Casanova, F., O’Loughlin, J., Martin, S., Beaumont, R. N., Wood, A. R., Watkins, E. R., et al. (2021). ‘Higher adiposity and mental health: causal inference using Mendelian randomization’. Human Molecular Genetics 30(24) pp. 2371-2382 ISSN: 1460-2083.

  66. Võsa, U. Claringbould, A., Westra, H., Bonder, M. J., Deelan, P., Zeng, B., et al. (2021). ‘Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression’. Nature Genetics 53(9) pp. 1300-1310 ISSN: 1546-1718.

  67. Mills, M. C., Tropf, F. C., Brazel, D. M., Zuydam, N. V. Vaez, A., eQTLGen Consortium; Bios Consortium, et al. (2021) ‘Publisher Correction: Identification of 371 genetic variants for age at first sex and birth linked to externalising behavior’. National Human Behavior 5(8) pp. 1111 ISSN: 2397-3374.

  68. Teo, K., Abeysekera, K. W. M., Adams, L., Aigner, E., Anstee, Q. M., Banales, J. M., et al. (2021) ‘rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis’. Journal of Hepatology 74(1) pp. 20-30 ISSN: 0168-8278.

2020

1.     Andersson, MK., Mangiapane, G., Nevado, PJ., Tsakaneli, A., Carlsson, T., Corda, G., et al. (2020) ‘ATR is a MYB regulated gene and potential therapeutic target in adenoid cystic carcinoma’. Oncogenesis, 9 (1) pp. 5. ISSN: 2157-9024

2.      Bibbo’, S., Lamolinara, A., Capone, E., Purgato, S., Tsakaneli, A., Panella, V., et al. (2020) ‘Repurposing a psychoactive drug for children with cancer: p27Kip1- dependent inhibition of metastatic neuroblastomas by Prozac’. Oncogenesis, 9 (1) pp. 3. ISSN: 2157-9024

3.      Boltersdorf, T., Ansari, J., Senchenkova, EY., Groeper, J., Pajonczyk, D., Vital, SA., et al. (2020) ‘Targeting of Formyl Peptide Receptor 2 for in vivo imaging of acute vascular inflammation’ Theranostics, 10 (15). pp. 6599 - 6614. ISSN: 0006-4971

4.      Brooks, BW., Sabo-Attwood, T., Choi, K., Kim, S., Kostal, J., LaLone, CA., et al. (2020) ‘Toxicology Advances for 21st Century Chemical Pollution’. One earth (Cambridge, Mass.), 2 (4). pp. 312- 316. ISSN: 2590-3330

5.      Capone, E., Lamolinara, A., Pastorino, F., Gentile, R., Ponziani, S., Di Vittorio, G., et al. (2020) ‘Targeting vesicular lgals3bp by an antibody-drug conjugate as novel therapeutic strategy for neuroblastoma.’ Cancers, 12 (10). pp. 1 - 18. ISSN: 2072-6694

6.      DeCordova, S., Shastri, A., Tsolaki, AG., Yasmin, H., Klein, L., Singh, S., et al. (2020) ‘Molecular Heterogeneity and Immunosuppressive Microenvironment in Glioblastoma’ Frontiers in immunology, 11. pp. 1402. ISSN: 1664-3224

7.      Ellis, T., Margiotta-Casaluci, L., Pottinger, TG., Morris, S., Reese, RA., Sumpter, JP., et al. (2020) ‘Immunoassays are not immune to errors: Examples from two studies of steroid output from freshwater trout farms’. General and comparative endocrinology, 285. pp. 113226. ISSN: 0016-6480

8.      Elliott, P., Muller, DC., Schneider-Luftman, D., Pazoki, R., Evangelou, E., Dehghan, A., et al. (2020) ‘Estimated 24-Hour Urinary Sodium Excretion and Incident Cardiovascular Disease and Mortality Among 398 628 Individuals in UK Biobank’. Hypertension (Dallas, Tex. 1979), 76 (3). pp. 683-691. ISSN: 0194-911X

9.      Ferluga, J., Yasmin, H., Al-Ahdal, MN, Bhakta, S., Kishore, U., (2020) ‘Natural and trained innate immunity against Mycobacterium tuberculosis’. Immunobiology, 225 (3). pp. 151951. ISSN: 0171-2985

10.  Gomez, I., Ward, B., Souilhol, C., Recarti, C., Ariaans, M., Johnston, J., et al. (2020) ‘Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium’ Nature communications, 11 (1). pp. 214. ISSN: 2041-1723

11.  Huerta Buitrago, B., Margiotta-Casaluci, L., Rodríguez Mozaz, S., Scholze, M., Winter, MJ., Barceló i Cullerés, D., et al. (2020) ‘Anti-anxiety drug and fish behavior: establishing the link between internal concentrations of oxazepam and behavioral effects’. Environmental toxicology and chemistry, ISSN: 0730-7268, 1552-8618

12.  Kale, K., Vishwekar, P., Balsarkar, G., Jassawalla, MJ., Alkahtani, S., Kishore, U., (2020) ‘Serum Levels of Collectins Are Sustained During Pregnancy: Surfactant Protein D Levels Are Dysregulated Prior to Missed Abortion’. Reproductive sciences, 27 (10). pp. 1894 - 1908. ISSN: 1933-7191

13.  Kishore, U., Bulla, R., Madan, T., (2020) ‘Editorial: Odyssey of Surfactant Proteins SP-A and SP-D: Innate Immune Surveillance Molecules’. Frontiers in immunology, 11. pp. 394. ISSN: 1664-3224

14.  Kishore, U., Ghebrehiwet, B., (2020) ‘C1q: A molecular bridge to innate and adaptive immunity’. ISSN: 1664-3224, 1664-3224

15.  Legler, J., Zalko, D., Jourdan, F., Jacobs, M., Fromenty, B., Balaguer, P., et al. (2020) ‘The GOLIATH Project: Towards an Internationally Harmonised Approach for Testing Metabolism Disrupting Compounds’. International journal of molecular sciences, 21 (10). pp. 3480. ISSN: 1661-6596, 1422-0067

16.  Lubyayi, L., Mawa, PA., Nabakooza, G., Nakibuule, M., Tushabe, JV., Serubanja, J., et al. (2020) ‘Maternal Latent Mycobacterium tuberculosis Does Not Affect the Infant Immune Response Following BCG at Birth: An Observational Longitudinal Study in Uganda’. Frontiers in immunology, 11. pp. 929. ISSN: 1664-3224

17.  Madan, T., Kishore, U., (2020) ‘Surfactant Protein D Recognises Multiple Fungal Ligands: A Key Step to Initiate and Intensify the Anti-fungal Host Defense’. Frontiers in cellular and infection microbiology, 10. pp. 229. ISSN: 2235-2988

18.  Mahony, C., Ashton, RS., Birk, B., Boobis, AR., Cull, T., Daston, GP., et. al. (2020) ‘New ideas for non-animal approaches to predict repeated-dose systemic toxicity: Report from an EPAA Blue Sky Workshop’. Regulatory toxicology and pharmacology, 114. ISSN: 0273-2300, 1096-0295

19.  Maslova, E., Shi, Y., Sjöberg, F., Azevedo, HS., Wareham, DW., McCarthy, RR., (2020) ‘An Invertebrate Burn Wound Model That Recapitulates the Hallmarks of Burn Trauma and Infection Seen in Mammalian Models’. Frontiers in microbiology, 11. pp. 998. ISSN: 1664-302X

20.  McCleary, S., Strong, R., McCarthy, RR., Edwards, JC., Howes, EL., Stevens, LM., et al. (2020) ‘Substitution of warthog NF-kB motifs into RELA of domestic pigs is not sufficient to confer resilience to African swine fever virus’. Scientific reports, 10 (1). pp. 8951. ISSN: 2045-2322

21.  Moses, RL., Dally, J., Lundy, FT., Langat, M., Kiapranis, R., Tsolaki, AG., et al. (2020) ‘Lepiniopsis ternatensis  sap stimulates fibroblast proliferation and down regulates macrophage TNF-⍺ secretion’ Fitoterapia, 141. pp. 104478. ISSN: 0367-326X

22.  Murugaiah, V., Agostinis, C., Varghese, PM., Belmonte, B., Vieni, S., Alaql, FA., et al. (2020) ‘Hyaluronic Acid Present in the Tumor Microenvironment Can Negate the Pro-apototic Effect of a Recombinant Fragment of Human Surfactant Protein D on Breast Cancer Cells’. Frontiers in Immunology, 11. pp. 1171. ISSN: 1664-3224

23.  Murugaiah, V., Tsolaki, AG., Kishore, U., (2020). ‘Collectins: Innate Immune Pattern Recognition Molecules’ Advances in experimental medicine and biology, 1204. pp. 75 -  127. ISSN: 0065-2598

24.  Murugaiah, V., Varghese, PM., Saleh, SM., Tsolaki, AG., Alrokayan, SH., Khan, HA., et al. (2020) ‘Complement- Independent Modulation of Influenza A Virus Infection by Factor H.' Frontiers in immunology, 11. pp. 355. ISSN: 1664-3224

25.  Omura, S., Sato, F., Park, A., Fujita, M., Nishio, K., Gavins, F., Tsunoda, I., (2020) ‘Bioinformatics Analysis of Gut Microbiota and CNS Transcriptome in Virus-Induced Acute Myelitis and Chronic Inflammatory Demyelination; Potential Association of Distinct Bacteria with CNS IgA upregulation. Frontiers in Immunology, section Mucosal Immunity.’ Frontiers in Immunology., 11. pp. 1138. ISSN: 1664-3224

26.  Pazoki, R., Lin, BD., van Eijk, KR., Schijven, D., de Zwarte, S., Guloksuz, S., et al. (2020) ‘Phenome-wide and genome-wide analyses of quality of life in schizophrenia’.. BJPsych open, 7 (1). pp. e13. ISSN: 2056-4724

27.  Pérez-Hernández, CA., Kern, CC., Butkeviciute, E., McCarthy, E., Dockrell, HM., Moreno-Altamirano, MMB., et al. (2020) ‘Mitochondrial Signature in Human Monocytes and Resistance to Infection in C. elegans During Fumarate-Induced Innate Immune Training’. Frontiers in immunology, 11.  pp. 1715. ISSN: 1664-3224

28.  Riaz, MS., Kaur, A., Shwayat, SN., Behboudi, S., Kishore, U., Pathan, AA., (2020) ‘Dissecting the Mechanism of IntracellularMycobacterium smegmatisGrowth Inhibition by Platelet Activating Factor C-16’. Frontiers in microbiology, 11. pp. 14. ISSN: 1664-302X, 1664-302X

29.  Rivetti, C., Allen, TEH., Brown, JB., Butler, E., Carmichael PL., Colbourne, JK., et al. (2020) ‘Vision of a near future: Bridging the human health-environment divide. Toward an integrated strategy to understand mechanisms across species for chemical safety assessment’. Toxicology in vitro, 62. pp. 1-9. ISSN: 0887-2333

30.  Robinson, O.,  Chadeau Hyam, M., Karaman, I., Climaco Pinto, R., Ala-Korpela, M., Handakas, E., et al. (2020) ‘Determinants of accelerated metabolomic and epigenetic ageing in a UK cohort’. Aging cell, 19 (6). pp. e13149 - n/a. ISSN: 1474-9718

31.  Siggins, MK., Lynskey, NN., Lamb, LE., Johnson, LA., Huse, KK., Pearson, M., et al. (2020) ‘Extracellular bacterial lymphatic metastasis drives Streptococcus pyogenes systemic infection’. Nature communications, 11 (1). pp. 4697. ISSN: 2041-1723

32.  Symonds, ALJ., Zheng, W., Miao, T., Wang, H., Wang, T., Kiome, R., et al. (2020) ‘Egr2 and 3 control inflammation, but maintain homeostasis, of PD-1 high memory phenotype CD4 T cells’. Life science alliance, 3 (9). pp. e202000766. ISSN: 2575-1077

33.  Thakur, G., Sathe, G., Kundu, I., Biswas, B., Gautam, P., Alkahtani, S., et al. (2021) ‘Membrane Interactome of a Recombinant Fragment of Human Surfactant Protein D Reveals GRP78 as a Novel Binding Partner in PC3, a Metastatic Prostate Cancer Cell Line’. Frontiers in immunology, 11. pp. 600660. ISSN: 1664-3224

34.  Thompson, WD., Beaumont, RN., Kuang, A., Warrington, NM., Ji, Y., Tyrrell, J., et al., (2021) ‘Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile’ Diabetologia, 64 (12). pp. 2790 - 2802. ISSN: 0012-186X

35.  Varghese, PM., Tsolaki, AG., Yasmin, H., Shastri, Abhishek., Ferluga, J., Vatish, M., et al. (2020) ‘Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies’ Immunobiology, 225(6). pp. 152008. ISSN: 0171-2985

36.  Vital, SA., Senchenkova, EY., Ansari, J., Gavins, F., (2020) 'Targeting AnxA1/Formyl Peptide Receptor 2 Pathway Affords Protection against Pathological Thrombo-Inflammation.’ Cells., 9 (11). pp. 1. ISSN: 2073-4409

37.  Võsa, U., Claringbould, A., Westra, HJ., Bonder, MJ., Deelen, P., Zeng, B., et al., (2021) ‘Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression’ Nature genetics, 53 (9).pp.1300 - 1310. ISSN: 1061-4036, 1546-1718

2019

1.      Agostinis, C., Mangogna, A., Bossi, F., Ricci, G., Kishore, U., Bulla, R., (2019) ‘Uterine Immunity and microbiota: A shifting paradigm’. Frontiers in immunology, 10. pp. 2387. ISSN: 1664-3224

2.     Agostinis, C., Masat, E., Bossi, F., Ricci, G., Menegazzi, R., Lombardelli, L., et al. (2019) ‘Transcriptomics and Immunological Analyses Reveal a Pro-angiogenic and Anti-inflammatory Phenotype for Decidual Endothelial Cells’. International Journal of molecular sciences, 20 (7). pp. 1604. ISSN: 1661-6596, 1422-0067

3.      Al-Qahtani, AA., Murugaiah, V., Bashir, HA., Pathan, AA., Abozaid, SM., Makarov, E., et al. (2019) ‘Full length human surfactant protein A inhibits influenza A virus infection of A549 lung epithelial cells: A recombinant form containing neck and lectin domains promotes infectivity’. Immunobiology (1979), 224 (3). pp. 408-418. ISSN: 0171-2985

4.     Ansari, J., Gavins, F.,(2019) ‘Ischemia-Reperfusion Injury in Sickle Cell Disease: From Basics to Therapeutics.’ The American journal of pathology, 189 (4). pp. 706 - 718. ISSN:0002-9440

5.     Armitage, EP., Senghore, E., Darboe, S., Barry, M., Camara, J., Bah, S., et al. (2019) ‘High burden and seasonal variation of paediatric scabies and pyoderma prevalence in the Gambia: A cross-sectional study’. PLoS neglected tropical diseases, 13 (10). pp. e0007801. ISSN: 1935-2727, 1935-2735

6.     Barzegar, M., Kaur, G., Gavins, F., Wang, Y., Boyer, CJ., Alexander, JS., (2019) ‘Potential therapeutic roles of stem cells in ischemia-reperfusion injury’. International journal of molecular sciences, 19 (4). pp. 1211. ISSN: 1661-6596, 1422-0067

7.     Becker, F.*, Gavins, F.*, Fontenot, J., Jordan, P., Yun, JY., Scott, R., et al. (2019) ‘Dynamic gut microbiome changes following regional intestinal lymphatic obstruction in primates.’ Pathophysiology. 2019;26:253-261. (*Authors contributed equally.)

8.     Becker, F., Romero, E., Goetzmann, J., Hasselschwert, DL., Dray, B., Vanchiere, J., et al. (2019) 'Endogenous Specialized Proresolving Mediator Profiles in a Novel Experimental Model of Lymphatic Obstruction and Intestinal Inflammation in African Green Monkeys.’ The American journal of pathology, 189 (10). pp. 1953 - 1972. ISSN: 0002-9440

9.     Boltersdorf, T., Ansari, J., Senchenkova, EY., Jiang, L., White, AJP., Coogan, M., et al. (2019) 'Development, characterisation, and in vitro evaluation of lanthanide-based FPR2/ALX-targeted imaging probes.' Dalton transactions : an international journal of inorganic chemistry, 48 (44). pp. 16764 - 16775. ISSN: 1477-9226

10.  Booth, P., McCarthy, R., (2019) ‘Developing high through put screening strategies to identify the next generation of antimicrobials’.  Access microbiology, 1 (10). ISSN: 2516-8290, 2516-8290

11.  DeCordova, S., Abdelgany, A., Murugaiah, V., Pathan, AA., Nayak, A., Walker, T., et al. (2019) ‘Secretion of functionally active complement factor H related protein 5 (FHR5) by primary tumour cells derived from Glioblastoma Multiforme patients’. Immunobiology (1979), 224 (5). pp. 625 - 631. ISSN: 0171-2985

12.  de Vries, PS., Brown, MR., Bentley, AR., Sung, YJ., Winkler, TW.,  Ntalla, I.,  et al. (2019) ‘Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions’. American journal of epidemiology, 188 (6). pp. 1033 - 1054. ISSN: 0002-9262, 1476-6256

13.  Evangelou, E., Gao, H., Chu, C., Ntritsos, G., Blakeley, P., Butts, AR., et al. (2019) ‘New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders’. Nature human behaviour, 3 (9). pp. 950-961. ISSN: 2397-3374, 2397-3374

14.  Guitérrez-Barranquero, JA., Reen, FJ., Parages, ML., McCarthy, R., Dobson, ADW., O’Gara, F., (2019) ‘Disruption of N-acyl-homoserine lactone-specific signalling and virulence in clinical pathogens by marine sponge bacteria’. Microbial biotechnology, 12 (5) pp. 1049 -  1063. ISSN: 1751-7915, 1751-7907

15.  Gunnarsson, L., Snape, JR., Verbruggen, B., Owen, SF., Kristiansson, E., Margiotta-Casaluci, L., et al. (2019) ‘Pharmacology beyond the patient - The environmental risks of human drugs’. Environment international, 129. pp. 320- 332. ISSN: 0160-4120

16.  Harris, SE., Hagenaars, SP., Ritchie, SJ., Marioni, RE., Fawns-Ritchie, C., Liewald, DCM., et al. (2019) ‘Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function’. Nature communications, 10 (1). pp. 2068. ISSN: 2041-1723

17.  Kumar, J., Murugaiah, V., Sotiriadis, G., Kaur, A., Jeyaneethi, J., Stumiolo, L., et al. (2019) ‘Surfactant Protein D as a Potential Biomarker and Therapeutic Target in Ovarian Cancer’. Frontiers in oncology, 9. pp. 542. ISSN: 2234-943X

18.  Lee, H., Kim, J., Kang, YA., Kim, DR., Sim, B., Zelmer, A., et al. (2019) ‘In vitro Mycobacterial Growth Inhibition in South Korean Adults With Latent TB Infection’. Frontiers in immunology, 10. pp. 896. ISSN: 1664-3224

19.  Lynskey, NN., Jauneikaite, E., Li, HK., Zhi, X., Turner, CE., Mosavie, M., et al. (2019) ‘Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study’. The Lancet infectious diseases, 19 (11). pp. 1209 - 1218. ISSN: 1473-3099

20.  Luykx, J., Pazoki, R., Lin, B., Guloksuz, S., Schijven, D., van Eijk, K., et al. (2019) ‘T168. Phenome-Wide and Genome-Wide Analyses of Quality of  Life in Patients with Psychosis’. Biological psychiatry (1969),  85 (10) pp. S194. ISSN: 0006-3223

21.  Mangogna, A., Agostinis, C., Bonazza, D., Belmonte, B., Zacchi, P., Zito, G., et al. (2019) ‘Is The Complement Protein C1q a Pro-  or Anti- tumorigenic Factor? Bioinformatics Analysis Involving Human Carcinomas’. Frontiers in immunology, 10 (MAY). pp. 865. ISSN: 1664-3224

22.  Mangogna, A., Belmonte, B., Agostinis, C., Zacchi, P., Iacopino, DG., Martorana, A., et al. (2019) ‘Prognostic Implications of the Complement Protein C1q in Gliomas’. Frontiers in immunology, 10. pp. 2366. ISSN: 1664-3224

23.  Margiotta-Casaluci, L., Dusza, H., Moreira, I., Winter, MJ., Prior, H., (2019) ‘Development of an adverse outcome pathway (AOP) for cardiotoxicity mediated by the blockade of L-type calcium channels’. Journal of pharmacological and toxicological methods, 99. pp. 106595. ISSN: 1056-8719

24.  Margiotta-Casaluci, L., Owen, SF., Rand-Weaver, M., Winter, MJ., (2019) ‘Testing the Translational Power of the Zebrafish: An Interspecies Analysis of Responses to Cardiovascular Drugs.’ Frontiers in pharmacology, 10. pp. 893. ISSN: 1663-9812

25.  McCarthy R., (2019) ‘ Maximum overdrive: Deegan try is a real Lyon tamer [Eire Region]’. Sun (Plainfield, III.: Homer Township, Lockport, Lemont ed.), ISSN: 0307-2681

26.  McCarthy, RR., Everett, HE., Graham, SP., Steinbach, F., Crooke, HR., (2019) ‘Head Start Immunity: Characterizing the Early Protection of C Strain Vaccine Against Subsequent Classical Swine Fever Virus Infection’. Frontiers in immunology, 10. pp. 1584. ISSN: 1664-3224

27.  McCarthy, RR., Ullah, MW., Booth, P., Pei, E., Yang, G., (2019) ‘The use of bacterial polysaccharides in bioprinting’. Biotechnology advances, 37 (8). pp. 107448. ISSN: 0734-9750

28.  McCarthy, RR., Ullah, MW., Pei, E., Yang, G., (2019) ‘Antimicrobial Inks: The Anti-Infective Applications of Bioprinted Bacterial Polysaccharides’. Trends in biotechnology (Regular ed.), 37 (11). pp. 1155-1159. ISSN: 0167-7799

29.  McCarthy, RR., Yu, M., Eilers, K., Wang, Y., Lai, E., Filloux, A., (2019) ‘Cyclic di-GMP inactivates T6SS and T4SS activity in Agrobacterium tumefaciens’. Molecular microbiology, 112 (2). pp. 632- 648. ISSN: 0950-382X

30.  Nieddu, V., Piredda, R., Bexell, D., Barton, J., Anderson, J., Sebire, N., et al. (2019) ‘Engineered human mesenchymal stem cells for neuroblastoma therapeutics’. Oncology reports, 42 (1) pp. 35 - 42. ISSN: 1021-335X

31.  Pandit, H., Kale, K., Yamamoto, H., Thakur, G., Rokade, S., Chakraborty, P., et al. (2019) ‘Surfactant Protein D Reverses the Gene Signature of Transepithelial HIV-1 Passage and Restricts the Viral Transfer Across the Vaginal Barrier’. Frontiers in immunology, 10. pp. 264. ISSN: 1664-3224

32.  Pazoki, R., (2019) ‘Cardiovascular disease, ABO locus, and markers of platelet functionality’. International journal of cardiology, 286. pp. 162-163. ISSN: 0167-5273

33.  Pazoki, R., Dehghan, A., Evangelou, E., Warren, H., Gao, H., Caulfield, M., et al. (2019) ‘Genetic Predisposition to High Blood Pressure and Lifestyle Factors: Associations With Midlife Blood Pressure Levels and Cardiovascular Events’. Circulation, 139 (2). pp. E2. ISSN: 0009-7322

34.  Pazoki, R., Evangelou, E., Mosen-Ansorena, D., Pinto, RC., Karaman, I., Blakeley, P., et al. (2019) ‘GWAS for urinary sodium and potassium excretion highlights pathways shared with cardiovascular traits’. Nature communication, 10 (1). pp. 3653 - 11. ISSN: 2041-1723

35.  Prabowo, SA., Painter, H., Zelmer, A., Smith, SG., Seifert, K., Amat, M., et al. (2019) ‘Fletcher HA. RUTI Vaccination Enhances Inhibition of Mycobacterial Growth ex vivo and Induces a Shift of Monocyte Phenotype in Mice’. Frontiers in immunology, 10. pp. 894. ISSN: 1664-3224

36.  Prabowo, SA., Smith, SG., Seifert, K., Fletcher, HA., (2019) ‘Impact of individual-level factors on Ex vivo mycobacterial growth inhibition: Associations of immune cell phenotype, cytomegalovirus-specific response and sex with immunity following BCG vaccination in humans’. Tuberculosis, 119. pp. 101876. ISSN: 1472-9792

37.  Prabowo, SA., Zelmer, A., Stockdale, L., Ojha, U., Smith, SG., Seifert, K., et al. (2019) ‘Historical BCG vaccination combined with drug treatment enhances inhibition of mycobacterial growth ex vivo in human peripheral blood cells’. Scientific reports, 9(1). pp. 4842. ISSN: 2045-2322

38.  Preiss, D., Swerdlow, D., Fatemifar, G., Faraway, R., Finan, C., Fairhurst-Hunter, Z., et al. (2019) ‘Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9’. BMC cardiovascular disorders, 19 (1). pp. 240. ISSN: 1471-2261

39.  Rabeeah, I., Kishore, U., Nal-Rogier, B., Shelton, H., (2019) ‘Influenza A Virus interactions with complement factor H’. Access microbiology, 1 (1A). ISSN: 2516-8290, 2516-8290

40.  Reen, FJ., Guitérrez-Barranquero, JA., McCarthy, RR., Woods, DF., Scarciglia, S., Adams, C., et al. (2019) ‘Quorum Sensing Signaling Alters Virulence Potential and Population Dynamics in Complex Microbiome-Host Interactomes’. Frontiers in microbiology, 10. pp. 2131. ISSN: 1664-302X

41.  Reglinski, M., Sriskandan, S., Turner, CE., (2019) ‘Identification of two new core chromosome-encoded superantigens in Streptococcus pyogenes; speQ and speR’. The Journal of infection, 78(5). pp. 358 - 363. ISSN: 0163-4453

42.  Senchenkova, EY., Ansari, J, Becker F., Vital, SA., Al-Yafeai, Z., Sparkenbaugh, EM., et al.  (2019) ‘Novel Role for the AnxA1-Fpr2/ALX Signaling Axis as a Key Regulator of Platelet Function to Promote Resolution of Inflammation.’ Circulation, 140 (4). pp. 319 - 335. ISSN: 0009-7322

43.  Senchenkova, EY., Russell, J., Yildirim, A., Granger, DN., Gavins, F., (2019) ‘Novel Role of T Cells and IL-6 (Interleukin-6) in Angiotensin II-Induced Microvascular Dysfunction. Hypertension.’ Hypertension, 73 (4). pp. 829 - 838. ISSN: 0194-911X

44.  Sharif, H., Singh, I., Kouser, L., Mösges, R., Bonny, MA., Karamani, A., et al. (2019) ‘ Immunologic mechanisms of a short-course of Lolium perenne peptide immunotherapy: A randomized, double-blind, placebo-controlled trial’. Journal of allergy and clinical immunology, 144 (3). pp. 738- 749. ISSN: 0091-6749, 1097-6825

45.  Sharma, H., Turner, CE., Siggins, MK., El-Bahrawy, M., Pichon, B., Kearns, A., et al. (2019) ‘Toxic Shock Syndrome Toxin 1 Evaluation and Antibiotic Impact in a Transgenic Model of Staphylococcal Soft Tissue Infection.’ mSphere, 4 (5). pp. e00665-19. ISSN: 2379-5042

46.  Tanner, R., Smith, SG., Van Meijgaarden, KE., Giannoni, F., Wilkie, M., Gabriele, L., et al. (2019) ‘Optimisation, harmonisation and standardisation of the direct mycobacterial growth inhibition assay using cryopreserved human peripheral blood mononuclear cells’. Jornal of immunological methods, 469. pp. 1 - 10. ISSN: 0022-1759

47.  Tanoue, R., Margiotta-Casaluci, L., Huerta, B., Runnalls, TJ., Eguchi, A., Nomiyama, K., et al. (2019) ‘Protecting the environment from psychoactive drugs: Problems for regulators illustrated by the possible effects of tramadol on fish behaviour’. The Science of the total environment, 664. pp. 915 - 926. ISSN: 0048-9697

48.  Thakur, G., Prakash, G., Murthy, V., Sable, N., Menon, S., Alrokayan, SH., et al. (2019) ‘Human SP-D Acts as an Innate Immune Surveillance Molecule Against Androgen-Responsive and Androgen- Resistant Prostate Cancer Cells’. Frontiers in oncology, 9. pp. 565. ISSN: 2234-943X

49.  Turner, CE., Bubba, L., Efstratiou, A., (2019) ‘Pathogenicity Factors in Group C and G Streptococci’. Microbiology spectrum, 7 (3). pp. 13. ISSN: 2165-0497

Turner, CE., Holden, MTG., Blane, B., Horner, C., Peacock, SJ., Sriskandan, S., (2019) ‘The. Emergence of successful Streptococcus pyogenes lineages through convergent pathways of capsule loss and recombination directing high toxin expression’. mBio, 10 (6). pp. e02521-19. ISSN: 2161-2129, 2150-7511