Organ-on-a-chip Research Group

We are an interdisciplinary group of experts from Life Sciences and Engineering developing microfluidic devices to culture tissues in order to replicate organ like functions. The engineered tissues can be used in pre-clinical trials as a substitute for animal testing, replicating more closely the human physiopathology. The group’s main research focus is on women’s health and developing four main organ-on-a-chip (OOC) models: the breast, vagina, ovary, and placenta.

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Areas of research

Specialist facilities

Partnerships and collaborations

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Human organs-on-chips

Credit: Wyss Institute at Harvard University

Browse our research projects

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Cell culture flasks in laboratory incubator.

Xcell: Studying cells and tissue biochemistry in simulated microgravity

3D illustration of x-chromosomes on a blue background thumbnail

Chromosome behaviour and dynamics after exposure to simulated microgravity

Engineering tissue specific scaffolds for organ-on-a-chip models

Vagina-on-a-Chip

Multifactorial impacts on early breast carcinogenesis

Organ-on-a-chip models for ovarian cancer

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Networks and Centres

Centre for Genome Engineering and Maintenance

A diverse research network focused on molecular, cellular, organismal and computational aspects of genome biology

Organ-on-a-Chip Technologies Network

This network is a joint MRC, EPSRC and BBSRC funded Technology Touching Life initiative, designed to capture, inspire and grow UK research activity in the Organ-on-a-Chip research field

DoC Lab

The group conducts research within two primary subsections, both based on microfluidic technology; point-of-care diagnostics and organ-on-a-chip systems