Dr Svetlana Ignatova
Reader - Advanced Bioprocessing
Quad North 041
- Email: svetlana.ignatova@brunel.ac.uk
- Tel: +44 (0)1895 266911
- Chemical Engineering
- College of Engineering, Design and Physical Sciences
Summary
Dr Svetlana Ignatova is a process chemist specialising in the area of separation and purification technologies and associated instrument design and its operation. She has over 30 years of experience in process development and scale up of continuous liquid-liquid extraction and chromatography with projects spanning across academia and industry, nationally and internationally. Her main research focus is on further improvements in speed, throughput, economy, resolution and efficiency of downstream processing of various materials including metal recovery, (bio)pharmaceuticals, natural products, particles, biological materials and waste streams valorisation, while using novel approaches and materials including bio-ionic liquids and deep eutectic solvents.
After joining Brunel University in 2003, she played an important role in the development of continuous dynamic extraction technology, often referred to as counter-current chromatography (CCC) technology, from “home-made” to “industrial competitive” and in its scale-up from analytical to pilot scale at the Brunel’s Advanced Bioprocessing Centre (ABC) through various separation trials carried out for the National Cancer Institute (USA), Pfizer, Syngenta, Shell and GSK.
Dr Ignatova is a founding member of the Department of Chemical Engineering where she has held a variety of leadership roles since 2018. She is currently Director of Teaching and Learning and responsible for the Design, Launch and Accreditation of both Undergraduate and Postgraduate Programmes within the Department.
Qualifications
- MChem in Separation Sciences, Moscow State University
- PhD in Separation sciences, Russian Academy of Sciences
Responsibility
- Director of Teaching and Learning (February 2018 – present)
- Senior Tutor (February 2018 – November 2021)
- Interim Head of Department (January-June 2022)
Newest selected publications
Lopez, BGC., Marcucci, MC., Rocco, SA., Sforça, ML., Eberlin, MN., Hewitson, P., et al. (2024) 'Preparative Fractionation of Brazilian Red Propolis Extract Using Step-Gradient Counter-Current Chromatography'. Molecules, 29 (12). pp. 2757 - 2757. ISSN: 1420-3049
Rehman, R., Zubair, M., Bano, A., Hewitson, P. and Ignatova, S. (2021) 'Isolation of industrially valuable α-Cedrol from essential oil of Platycladus orientalis (Thuja orientalis) leaves using linear gradient counter current chromatography'. Industrial Crops and Products, 176. pp. 114297 - 114297. ISSN: 0926-6690
Suleman, S., Schrubaji, K., Filippou, C., Ignatova, S., Hewitson, P., Huddleston, J., et al. (2021) 'Rapid and inexpensive purification of adenovirus vectors using an optimised aqueous two-phase technology'. Journal of Virological Methods, 299. pp. 1 - 9. ISSN: 0166-0934 Open Access Link
Peng, A., Hewitson, P., Sutherland, IA., Chen, L. and Ignatova, S. (2018) 'The effect of increasing centrifugal acceleration/force and flow rate for varying column aspect ratios on separation efficiency in Counter-Current Chromatography'. Journal of Chromatography A, 1581-1582. pp. 80 - 90. ISSN: 0021-9673 Open Access Link
Peng, A., Hewitson, P., Sutherland, I., Chen, L. and Ignatova, S. (2018) 'How changes in column geometry and packing ratio can increase sample load and throughput by a factor of fifty in Counter-Current Chromatography'. Journal of Chromatography A, 1580. pp. 120 - 125. ISSN: 0021-9673 Open Access Link