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Dr Svetlana Ignatova
Reader - Advanced Bioprocessing

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Lopez, BGC., Marcucci, MC., Rocco, SA., Sforça, ML., Eberlin, MN., Hewitson, P., et al. (2024) 'Preparative Fractionation of Brazilian Red Propolis Extract Using Step-Gradient Counter-Current Chromatography'. Molecules, 29 (12). pp. 2757 - 2757. ISSN: 1420-3049

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Rehman, R., Zubair, M., Bano, A., Hewitson, P. and Ignatova, S. (2021) 'Isolation of industrially valuable α-Cedrol from essential oil of Platycladus orientalis (Thuja orientalis) leaves using linear gradient counter current chromatography'. Industrial Crops and Products, 176. pp. 114297 - 114297. ISSN: 0926-6690

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Suleman, S., Schrubaji, K., Filippou, C., Ignatova, S., Hewitson, P., Huddleston, J., et al. (2021) 'Rapid and inexpensive purification of adenovirus vectors using an optimised aqueous two-phase technology'. Journal of Virological Methods, 299. pp. 1 - 9. ISSN: 0166-0934

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Peng, A., Hewitson, P., Sutherland, IA., Chen, L. and Ignatova, S. (2018) 'The effect of increasing centrifugal acceleration/force and flow rate for varying column aspect ratios on separation efficiency in Counter-Current Chromatography'. Journal of Chromatography A, 1581-1582. pp. 80 - 90. ISSN: 0021-9673

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Peng, A., Hewitson, P., Sutherland, I., Chen, L. and Ignatova, S. (2018) 'How changes in column geometry and packing ratio can increase sample load and throughput by a factor of fifty in Counter-Current Chromatography'. Journal of Chromatography A, 1580. pp. 120 - 125. ISSN: 0021-9673

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DeAmicis, C., Yang, Q., Bright, C., Edwards, NA., Harris, GH., Kaur, S., et al. (2017) 'Development of a Scalable and Sustainable High Performance CounterCurrent Chromatography (HPCCC) Purification for Spinosyn A and Spinosyn D from Spinosad'. Organic Process Research and Development, 21 (10). pp. 1638 - 1643. ISSN: 1083-6160

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Cardenas-Fernandez, M., Bawn, M., Bennett, C., Penumathsa, B., Subrizi, F., Suhaili, N., et al. (2017) 'An Integrated Biorefinery Concept for Conversion of Sugar Beet Pulp into Value-added Chemicals and Pharmaceutical Intermediates'. Faraday Discuss., 202. pp. 415 - 431. ISSN: 1359-6640

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Cheel, J., Bogdanová, K., Ignatova, S., Garrard, I., Hewitson, P., Kolář, M., et al. (2016) 'Dimeric cyanobacterial cyclopent-4-ene-1,3-dione as selective inhibitor of Gram-positive bacteria growth: Bio-production approach and preparative isolation by HPCCC'. Algal Research, 18. pp. 244 - 249. ISSN: 2211-9264

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Zhang, M., Ignatova, S., Hu, P., Liang, Q., Wang, Y., Sutherland, IA., et al. (2012) 'Cost-efficient and process-efficient separation of geniposide from Gardenia jasminoides Ellis by high-performance counter-current chromatography'. Separation and Purification Technology, 89. pp. 193 - 198. ISSN: 1383-5866

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Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN., van den Heuvel, R. and Grudzien, L. (2011) 'Liquid-liquid chromatography: why a liquid stationary phase is so exciting'.Separation Science Europe: New Horizons in Separation and Detection Techniques. The Royal Institution, London, UK. 10 - 11 October. [unpublished]

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Sutherland, I., Ignatova, S., Hewitson, P., Janaway, L., Wood, P., Edwards, N., et al. (2011) 'Scalable technology for the extraction of pharmaceutics (STEP): The transition from academic knowhow to industrial reality'. Journal of Chromatography A, 1218 (36). pp. 6114 - 6121. ISSN: 1873-3778

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Ignatova, S., Sumner, N., Colclough, N. and Sutherland, I. (2011) 'Gradient elution in counter-current chromatography: A new layout for an old path'. Journal of Chromatography A, 1218 (36). pp. 6053 - 6060. ISSN: 1873-3778

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Ignatova, S., Hewitson, P., Mathews, B. and Sutherland, I. (2011) 'Evaluation of dual flow counter-current chromatography and intermittent counter-current extraction'. Journal of Chromatography A, 1218 (36). pp. 6102 - 6106. ISSN: 0021-9673

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Ignatova, SN. (2011) 'Role of countercurrent chromatography in modernisation of Chinese herbal medicines'.World Congress of Chinese Medicine (WCCM2011). London, UK. 2 - 3 September. [unpublished]

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Sutherland, IA., Ignatova, SN., Simmonds, M. and Sendker, J. (2011) 'Good practice in TCMs (GPTCM): preliminary results on the quality of botanical origin, processing and extraction information contained in papers on Cornus Officinalis in the last three years'.The 10th Meeting of Consortium for Globilisation of Chinese Medicine (CGCM2011). Shanghai, China. 26 - 28 August. [unpublished]

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Ignatova, SN., Douillet, N., Hewitson, P., Thickitt, C., Viliminot, E., Johns, D., et al. (2011) 'API recovery from pharmaceutical waste streams by high performance counter-current chromatography (HPCCC) and intermittent counter-current extraction (ICcE)'.International Symposium, Exhibit and Workshops on Preparative and Process Chromatography (PREP 2011). Boston, USA. 10 - 13 July. AMER CHEMICAL SOC. pp. 236 - 237. ISSN: 0065-7727

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DeAmicis, C., Edwards, NA., Giles, MB., Harris, GH., Hewitson, P., Janaway, L. and et al. (2011) 'Comparison of preparative reversed phase liquid chromatography and countercurrent chromatography for the kilogram scale purification of crude spinetoram insecticide'. Journal of Chromatography A, 1218 (36). pp. 6122 - 6127. ISSN: 0021-9673

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Hewitson, P., Ignatova, S. and Sutherland, I. (2011) 'Intermittent counter-current extraction-effect of the key operating parameters on selectivity and throughput'. Journal of Chromatography A, 1218 (36). pp. 6072 - 6078. ISSN: 0021-9673

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Zhang, M., Ignatova, S., Hu, P., Liang, Q., Wang, Y., Sutherland, IA., et al. (2011) 'Development of a strategy and process parameters for a green process in counter-current chromatography: Purification of tanshinone IIA and cryptotanshinone from Salvia miltiorrhiza Bunge as a case study'. Journal of Chromatography A, 1218 (36). pp. 6031 - 6037. ISSN: 1873-3778

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Ignatova, SN., Hewitson, P. and Sutherland, IA. (2010) 'New ways to solve old problems: purification of waste streams'.13th Symposium on Preparative and Industrial Chromatography and Allied Techniques (SPICA2010). Stockholm, Sweden. 12 - 15 September. [unpublished]

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Hewitson, P., Ignatova, SN. and Sutherland, IA. (2010) 'Effect of the key operating parameters on the efficiency of intermittent counter-current extraction'.6th International Symposium on Countercurrent Chromatography (CCC2010). Lyon, France. 28 - 30 July. [unpublished]

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Ignatova, SN., Sumner, N., Colclough, N. and Sutherland, IA. (2010) 'Gradient elution in counter-current chromatography: a new layout for an old path'.6th International Symposium on Countercurrent Chromatography (CCC2010). Lyon, France. 28 - 30 July. [unpublished]

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Ignatova, SN., Hewitson, P. and Sutherland, IA. (2010) 'χEvaluation of dual flow counter-current chromatography and intermittent counter-current extraction'.6th International Symposium on Countercurrent Chromatography (CCC2010). Lyon France. 28 - 30 July. [unpublished]

Conference paper | Cite

Sutherland, IA., Ignatova, SN., Hewitson, P., Janaway, L., Wood, P., Edwards, N., et al. (2010) 'Scalable technology for the extraction of pharmaceutics (STEP): the transition from academic knowhow to industrial reality'.6th International Symposium on Countercurrent Chromatography (CCC2010). Lyon, France. 28 - 30 July. [unpublished]

Conference paper | Cite

Zhang, M., Ignatova, SN., Hu, P., Liang, Q., Wang, Y., Luo, G., et al. (2010) 'Exploiting counter-current chromatography as a green process: purification of tanshinone IIA and cryptotanshinone from Salvia miltiorrhiza Bunge as a case study'.6th International Symposium on Countercurrent Chromatography (CCC2010). Lyon, France. 28 - 30 July. [unpublished]

Conference paper | Cite

Ignatova, S., Hawes, D., van den Heuvel, R., Hewitson, P. and Sutherland, IA. (2010) 'A new non-synchronous preparative counter-current centrifuge – the next generation of dynamic extraction/chromatography devices with independent mixing and settling control, which offer a step change in efficiency'. Journal of Chromatography A, 1217 (1). pp. 34 - 39. ISSN: 0021-9673

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Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'Scale up in countercurrent chromatography'.CCC Workshop. Federal University of Rio de Janiero, Brazil. 14 - 18 December. [unpublished]

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Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'CCC solvent systems for natural products separations'.CCC Workshop. Federal University of Rio de Janiero, Brazil. 14 - 18 December. [unpublished]

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Sutherland, IA., Hewitson, P. and Ignatova, S. (2009) 'Scale-up of counter-current chromatography: Demonstration of predictable isocratic and quasi-continuous operating modes from the test tube to pilot/process scale'. Journal of Chromatography A, 1216 (50). pp. 8787 - 8792. ISSN: 0021-9673

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Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'High capacity CCC for fast isolation of natural products'.Royal Society of Chemistry Conference "Functional Molecules from Natural Sources". Oxford, UK. 6 - 8 July. [unpublished]

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Ye, H., Ignatova, S., Peng, A., Chen, L. and Sutherland, IA. (2009) 'Optimising resolution for a preparative separation of Chinese herbal medicine using a surrogate model sample system'. Journal of Chromatography A, 1216 (26). pp. 5101 - 5105. ISSN: 0021-9673

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Hawes, D., Ignatova, SN., van den Heuvel, R. and Sutherland, IA. (2009) 'Non-synchronous preparative CCC – the next generation counter-current centrifuge where phase separation and mixing can be independently controlled'.15th International Conference on Biopartitioning and Purification (BPP2009). Brunel University, Uxbridge, UK. 14 - 19 June. [unpublished]

Conference paper | Cite

Rubio, N., Ignatova, SN., Sutherland, IA. and Minguillon, C. (2009) 'Multiple dual-mode counter-current chromatography applied to chiral separations'.15th International Conference on Biopartitioning and Purification (BPP2009). Brunel University, Uxbridge, UK. 14 - 19 June. [unpublished]

Conference paper | Cite

Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'The role of counter-current chromatography in the fractionation and identification of plant based extracts'.International Exhibition-Congress on Chemical Engineering, Environmental Protection and Biotechnology (ACEMA2009). Frankfurt am Main, Germany. 11 - 15 May. [unpublished]

Conference paper | Cite

Hewitson, P., Ignatova, S., Ye, H., Chen, L. and Sutherland, I. (2009) 'Intermittent counter-current extraction as an alternative approach to purification of Chinese herbal medicine'. Journal of Chromatography A, 1216 (19). pp. 4187 - 4192. ISSN: 0021-9673

Journal article | Cite

Sutherland, IA., Hewitson, P. and Ignatova, S. (2009) 'New 18-l process-scale counter-current chromatography centrifuge'. Journal of Chromatography A, 1216 (19). pp. 4201 - 4205. ISSN: 0021-9673

Journal article | Cite

Zhang, M., Ignatova, S., Liang, Q., Wu Jun, F., Sutherland, I., Wang, Y. and et al. (2009) 'Rapid and high-throughput purification of salvianolic acid B from Salvia miltiorrhiza Bunge by high-performance counter-current chromatography'. Journal of Chromatography A, 1216 (18). pp. 3869 - 3873. ISSN: 0021-9673

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Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'Developing a large scale purification protocol'.4th International Conference on Bioprospecting (BIOPROSP2009). Radisson SAS Hotel, Tromso, Norway. 24 - 25 February. [unpublished]

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Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2009) 'Large scale purification of biomolecules: advantages of a liquid stationary phase'.4th International Conference on Bioprospecting (BIOPROSP2009). Radisson SAS Hotel, Tromso, Norway. 24 - 25 February. [unpublished]

Conference paper | Cite

Rubio, N., Ignatova, S., Minguillón, C. and Sutherland, IA. (2009) 'Multiple dual mode countercurrent chromatography applied to chiral separations using a (S)-naproxen derivative as chiral selector'. Journal of Chromatography A, 1216 (48). pp. 8505 - 8511. ISSN: 0021-9673

Journal article | Cite

Berthod, A., Ignatova, S. and Sutherland, IA. (2009) 'Advantages of a small-volume counter-current chromatography column'. Journal of Chromatography A, 1216 (19). pp. 4169 - 4175. ISSN: 0021-9673

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Ye, H., Ignatova, S., Luo, H., Li, Y., Peng, A., Chen, L. and et al. (2008) 'Preparative separation of a terpenoid and alkaloids from Tripterygium wilfordii Hook. f. using high-performance counter-current chromatography: comparison of various elution and operating strategies'. Journal of Chromatography A, 1213 (2). pp. 145 - 153. ISSN: 0021-9673

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Garrard, I., Sutherland, I., Fisher, D., Ignatova, SN. and van den Heuvel, R. (2008) 'Dynamic extraction: an innovative, scaleable processing technology'.Scientific Update Conference, The Scale Up of Chemical Processes. Sheraton Hotel, Rome, Italy. 15 - 17 September. [unpublished]

Conference paper | Cite

Hewitson, P., Ignatova, SN., Ye, H., Chen, L. and Sutherland, IA. (2008) 'Intermittent counter-current extraction as an alternative approach to purification of chinese herbal medicine'.5th International Conference on Countercurrent Chromatography (CCC2008). Rio de Janeiro, Brazil. 26 - 29 July. [unpublished]

Conference paper | Cite

Hawes, D., Ignatova, SN., van den Heuvel, R. and Sutherland, IA. (2008) 'Non-synchronous preparative CCC - the next generation countercurrent centrifuge where phase separation and mixing can be independently controlled'.5th International Conference on Countercurrent Chromatography (CCC2008). Rio de Janeiro, Brazil. 26 - 29 July. [unpublished]

Conference paper | Cite

Ye, H., Ignatova, SN., Chen, L. and Sutherland, IA. (2008) 'Optimising resolution for a preparative separation of Chinese herbal medicine using a surrogate model sample system'.5th International Conference on Countercurrent Chromatography (CCC2008). Rio de Janeiro, Brazil. 26 - 29 July. [unpublished]

Conference paper | Cite

Ignatova, S., Wood, P., Hawes, D., Janaway, L., Keay, D. and Sutherland, I. (2007) 'Feasibility of scaling from pilot to process scale'. Journal of Chromatography A, 1151 (1-2). pp. 20 - 24. ISSN: 0021-9673

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Wood, P., Ignatova, S., Janaway, L., Keay, D., Hawes, D., Garrard, I. and et al. (2007) 'Counter-current chromatography separation scaled up from an analytical column to a production column'. Journal of Chromatography A, 1151 (1-2). pp. 25 - 30. ISSN: 0021-9673

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Chen, LJ., Zhang, Q., Yang, GL., Fan, LY., Tang, J., Garrard, I., et al. (2007) 'Rapid purification and scale-up of honokiol and magnolol using high-capacity high-speed counter-current chromatography'. Journal of Chromatography A, 1142 (2). pp. 115 - 122. ISSN: 0021-9673

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