Impact and Dissemination Publications Grants and Contracts Presentations DeAmicis, C, Edwards, N.A., Giles, M.B., Harris, G.H., Hewitson, P., Janaway, L. and Ignatova, S. (2011) Comparison of preparative reversed phase liquid chromatography and countercurrent chromatography for the kilogram scale purification of crude spinetoram insecticide, J. Chromatogr. A., 1218, 6122-6127 de Folter, J. and Sutherland, I.A. (2011) Probabilistic model for immiscible separations and extractions (ProMISE), J. Chromatogr. A, 1218, 6009-6014 Hewitson, P., Ignatova, S. and Sutherland, I.A. (2011) Intermittent counter-current extraction – effect of the key operating parameters on efficiency, J. Chromatogr. A, 1218, 6072-6078 Ignatova, S., Hewitson, P., Mathews, B. and Sutherland, I.A. (2011) Evaluation of dual flow counter-current chromatography and intermittent counter-current extraction, J. Chromatogr. A, 1218, 6102-6106 Ignatova, S., Sumner, N., Colclough, N. and Sutherland, I.A. (2011) Gradient elution in Counter-Current Chromatography: a new layout for an old path, J. Chromatogr. A, 1218, 6053-6060 Sutherland, I.A., Hewitson, P. and de Folter, J. (2011) Toroidal Coil Chromatography: the effect of scale-up and “g” field on stage efficiency, J. Chromatogr. A, 1218, 6144-6147 Sutherland, I.A., Hewitson, P. Sieber, R., van den Heuvel, R., Arbenz, L., Kinkel J. and Fisher, D. (2011) Scale-up of protein purifications using aqueous two-phase systems: comparing multilayer toroidal coil chromatography with centrifugal partition chromatography, J. Chromatogr. A., 1218, 5527-5530 Sutherland, I.A., Ignatova, S., Hewitson, P., Janaway, L., Wood, P., Edwards, N., Harris, G., Guzlek, H., Keay, D., Freebairn, K., Johns, D., Douillet, N., Thickitt, C., Vilminot E. and Mathews, B. (2011) Scalable Technology for the Extraction of Pharmaceutics (STEP): the transition from academic knowhow to industrial reality, J. Chromatogr. A., 1218, 6114-6121 van den Heuvel, R.N.A.M., König, C.S.(2011) Improved g-level calculations for coil planet centrifuges, J. Chromatogr. A, 1218, 6038-6043 Wei, Y., Xie, Q., Fisher, D. and Sutherland, I.A. (2011) Separation of patuletin-3-O-glucoside,astragalin,quercetin,kaempferoland isorhamnetin from Flaveria bidentis (L.) Kuntzebyelution-pump-out high-performance counter-currentchromatography, J. Chromatogr. A, 1218, 6206-6211 Wei, Y., Razwan Sardar, M., Sutherland, I.A. and Fisher, D. (2011) Separation of Delphinidin-3-O-sambubioside, Cyanidin-3-O-sambubioside and p-Coumaric Acid from Cranberry by CCC Followed by prep-HPLC Using Robotic CCC Solvent System Selection, Chromatographia, 74, 367-373 Zhang, M., Ignatova, S., Hu, P., Liang, Q., Wang, Y., Luo, G. Wujun, F. and Sutherland, I.A. (2011) Development of a strategy and process parameters for a green process in counter-current chromatography: Purification of tanshinone IIA and cryptotanshinone from Salvia miltiorrhiza Bunge as a case study, J. Chromatogr. A, 1218, 6031-6037 Fisher, D & Przybycien (2010) Introduction to Special Issue: 15th International Conference on Biopartitionig and Purification Separation Science and Technology 45, 2142-2143 Garrard IJ and Fisher D. (2010) High capacity countercurrent chromatography for fast isolation of natural products. Chapter in book Functional Molecules from Natural Sources from conference at Oxford, July 2009. Eds: SK Wrigley, R Thomas, N Nicholson and CT Bedford, Royal Society of Chemistry Publishing, Cambridge Guan, Y.H., Fisher, D. and Sutherland, I.A. (2010) Protein separation using toroidal columns by type-J synchronous counter-current chromatography towards preparative separation, J. Chromatogr. A., 1217, 3525-3530 Ignatova, S.N., Hawes, D., van den Heuvel, R., Hewitson, P. and Sutherland, I.A. (2010) A new non-synchronous preparative counter-current centrifuge – the next generation of dynamic extraction/chromatography devices with independent mixing and settling control, which offer a step change in efficiency, J. Chromatogr. A., 1217, 34-39 Qi, X., Ignatova, S., Luo, G., Liang, Q., WuJun, F., Wang, Y. and Sutherland, I.A. (2010) Preparative isolation and purification of ginsenosides Rf, Re, Rd and Rb1 from the roots of Panax Ginseng with a salt/containing solvent system and flow-step gradient by high performance counter-current chromatography coupled with evaporative light scattering, J. Chromatogr. A., 1217, 1995 – 2001 Berthod, A., Ignatova, S. and Sutherland, I.A. (2009) Advantages of a Small Volume CCC Column, J. Chromatogr. A., 1216, 4169-4175 Berthod, A., Maryutina, T,, Spivakov, B., Shpigun, O. and Sutherland, I.A. (2009) Countercurrent Chromatography in Analytical Chemistry, International Union of Pure and Applied Chemistry, Analytical Chemistry Division, Pure Appl. Chem., 81(2), 355-387 De Folter, J. and Sutherland, I.A. (2009) Universal Counter Current Chromatography modelling based on Counter Current Distribution, J. Chromatogr. A., 1216, 4218-4224 Guan, Y.H., Bourton, E., Hewitson, P., Sutherland, I.A. & Fisher, D. (2009) The Importance of Column Design for Scaleable Protein Separation using Aqueous Two Phase Systems on J-type Countercurrent Chromatography, Sep. Purif. Technol., 65, 79-85 Hewitson, P., Ignatova, S., Ye, H., Chen, L. and Sutherland, I.A., (2009) Intermittent Counter-current Extraction as an Alternative Approach to Purification of Chinese Herbal Medicine, J. Chromatogr. A., 1216, 4187-4192 Leitao, G.G., Berthod, A., Conway, W. and Sutherland, I.A. (2009) Foreword for CCC2008 Special Edition of the Journal of Chromatography A., J. Chromatogr. A., 1216 (19), 4135-4139 Rubio, N., Ignatova, S., Minguillon, C. and Sutherland, I.A. (2009) Multiple dual mode Countercurrent chromatography applied to chiral separations using a (S)-naproxen derivative as chiral selector, J. Chromatogr. A., 1216, 8505-8511 Skalicka-Wozniak K, Mroczek T, Garrard I.J, Glowniak K. (2009) Isolation of the new minor constituents dihydropyranochromone and furanocoumarin from fruits of Peucedanum alsaticum L. by high speed counter-current chromatography, Journal Chromatography A., 1216, 5669-5675 Sutherland, I.A. and Fisher, D. (2009) Role of counter-current chromatography in themodernisation of Chinese herbal medicines, J. Chromatogr. A., 1216, 740-753 Sutherland, I.A., Hewitson, P. and Ignatova, S. (2009) A New 18 Litre Process Scale Counter-Current Chromatography Centrifuge, J. Chromatogr. A., 1216, 4201-4205 Sutherland, I.A., Hewitson, P. and Ignatova, S. (2009) Scale-up of counter-current chromatography: demonstration of predictable isocratic and quasi-continuous operating modes from the test tube to pilot/process scale, J. Chromatogr. A., 1216, 8787-8792 van den Heuvel, R., Mathews, B., Dubant, S. and Sutherland, I.A. (2009) Continuous counter-current extraction on an industrial sample using dual-flow counter-current chromatography, J. Chromatogr. A., 1216, 4147-4153 van den Heuvel, R. and Sutherland, I.A. (2009) Phase distribution visualisation in continuous counter-current extraction, J. Chromatogr. A., 1216, 4252-4257 Wei, Y., Xie, Q., Fisher, D. and Sutherland, I.A. (2009) Preparative Isolation of Imperatorin, Oxypeucedanin and Isoimperatorin from A Traditional Chinese Herb Using A High-Speed Counter-Current Chromatography Strategy Based on Optimization of Rapid Flow Rate, Chromatographia, 70 (7-8), 1185-1189 Ye, H., Ignatova, S., Peng, A., Chen, L., Sutherland, I. (2009) Optimising resolution for a preparative separation of Chinese herbal medicine using a surrogate model sample system, J. Chromatogr. A., 1216 (26), 5101-5105 Zhang, M., Ignatova, S., Liang, Q., Wu Jun, F., Sutherland, I.A., Wang, Y. and Luo, G. (2009) Rapid and high-throughput purification of salvianolic acid B from Salvia miltiorrhiza Bunge by high-performance counter-current chromatography, J. Chromatogr. A., 1216 (18), 3869-3873 Garrard, I.J., Fisher, D. and Sutherland, I.A. (2008) Dynamic extraction: A high-speed, high-capacity purification process that is rapidly scalable, LC-GC North America, 26, (5), 424-438 Sutherland, I.A., Audo, G., Bourton, E., Couillard, F., Fisher, D., Garrard, I., Hewitson, P. and Intes, O. (2008) Rapid linear scale-up of a protein separation by centrifugal partition chromatography, J. Chromatogr. A., 1190, 57-62 Ye, H., Ignatova, S., Luo, H., Li, Y., Peng, A., Chen, L., Sutherland, I. (2008) Preparative separation of a terpenoid and alkaloids from Tripterygium wilfordii Hook. f. using high-performance counter-current chromatography: comparison of various elution and operating strategies, J. Chromatogr. A., 1213, 145-153 Yuan, Y., Wang, B., Chen, L-J., Luo, H., Fisher, D., Sutherland, I.A. and Wei, Y-Q. (2008) How to realize the linear scale-up process for the rapid purification using high-performance counter-current chromatography, J. Chromatogr. A., 1194, 192-198 Yuan, Y., Hou,W., Tang, M., Luo, H., Chen, L., Guan, Y.H. and Sutherland, I.A. (2008) Separation of Flavonoids from the Leaves of Oroxylum indicum by High-Speed Counter-Current Chromatography, Chromatographia, 68 (11-12), 885-892 EPSRC CASE award with AstraZeneca, Development of Counter-Current Chromatography Methodology to Facilitate the Rapid Separation of Pharmaceutical Discovery Compounds, October 2011 – September 2015, Svetlana Ignatova primary supervisor, Ian Sutherland 2nd supervisor. Guangzhou Xiangxue Pharmaceuticals Co. Ltd., Industrial Studentship, Fractionation of Ginseng using Counter-Current Chromatography and Scale-Up for the Separation and Purification of Effective Components, PI Svetlana Ignatova, co-PI Ian Sutherland, R85103, January 1, 2011 to December 31, 2012 Brunel University Knowledge Transfer Secondment Scheme, BioFocus Knowledge Transfer Secondment for New Technology for Drug Discovery, PI Svetlana Ignatova, co-PI Ian Sutherland, LBF009, January 2011- August 2011. Pierre Fabre Institut de Reche, Analytical conditions for Marcrocarpals Content, PI Svetlana Ignatova, co-PI Ian Sutherland, R30044, December 2010- September 2011. Technology Strategy Board: Feasibility Studies for Responsible Development of Nanoscale Technologies: Eco-Continuous Flow Process for the Separation and Sorting of Carbon Nanomaterials, PI Chris Price (Archimedes Polymer Technologies (UK) Ltd; co-PIs Wenhui Song, Svetlana Ignatova and Ian Sutherland. Grant No. TP 10566-52301, May 1 2011 to October 31 2011. NIH, Washington, USA, Research Project Award in collaboration with St Georges Hospital University, London. Microbicide Innovation Programme. Lead Prof. Julian Ma (St Georges) PI at Brunel Ian Garrard, Co-PI Derek Fisher, Sep 2010 – Aug 2013. Dynamic Extractions Ltd., Sub-contract separations for Clients (co-PIs Peter Hewitson and Svetlana Ignatova), July 2010 – March 2011 Technology Strategy Board High Value Chemicals Feasibility, Isolation and purification of pure sennosides, a high value pharmaceutical ingredient, using the waste from the processing of natural senna pods, April 1, 2010 – Sept 30, 2010 with Phytovation (lead Andrew Begin); PI Ian Garrard; co-PIs Svetlana Ignatova and Ian Sutherland. Grant No: HVCF/130235/BW033H – Apr 2010 – Sept 2010 Park Seed Fund, Production process to generate controlled-size polymer nanoparticles and nanocapsules for medical use (co-PIs Dr Wenhui Song, Dr Svetlana Ignatova and Ian Sutherland), March 2010 – Feb 2011 Technology Strategy Board High Value Manufacturing Competition, Scalable Technology for the Extraction of Pharmaceuticals (STEP), August 2009 – July 2012 with GSK (lead Keith Freebairn); Pfizer, Dynamic Extractions – PI Ian Sutherland; co-PIs Svetlana Ignatova and Peter Hewitson. Grant No: TP14/HVM/6/I/BD506K – Sept 2009 – Aug 2012 Dynamic Extractions Ltd., Sub-contract separation for Dow Chemicals (co-PIs Peter Hewitson and Svetlana Ignatova), April 2009 – May 2009 Guangzhou Xiangxue Ltd., “Fractionation of Ginseng using Countercurrent Chromatography and its Scale-up” (PI Ian Sutherland with Svetlana Ignatova), R85051, January 14, 2009 – 14th April, 2009. Shell Global Solutions, Fractionation of Algal Biomass by Countercurrent Chromatography (CCC), (PIs Ian Garrard, Svetlana Ignatova, Peter Hewitson and Ian Sutherland), May 2009 – July 2009 Solvay Pharmaceuticals: The Purification of Influenza Viral Proteins by Countercurrent Chromatography. PI Ian Garrard, Co-PI Derek Fisher, Dec 2008- Dec 2009 BBSRC Industrial CASE award with Lonza Biologics, Slough, Purification of Monoclonal Antibodies using Countercurrent Chromatography, Ian Garrard primary supervisor, Derek Fisher as secondary supervisor Awarded October 2008 – September 2012. HEIF4, “High Value Manufacturing for the Pharmaceutical Industry” (PI Ian Sutherland), August 1, 2008 – July 31st, 2011. BBSRC Grant Ref: BB/FOF/206, Validation of the commercial potential of a new dynamic extraction manufacturing process for proteins and nanoplexes Fernando, S, Garrard, I , Allen, L and Fisher, D. (2011) Successful monoclonal antibody purification using counter current chromatography (CCC): Finding the balance between retention of biological activity and high resolution separation, Bioprocessing UK, Glasgow, Nov 2011 (Poster, bursary prize winner) Garrard, I. (2011) Liquid-Liquid Chromatography: Why a Liquid Stationary Phase is So Exciting, Separation Science Europe: New Horizons in Separation and Detection Techniques, 10-11 October, 2011, The Royal Institution, London, UK (Oral Presentation) Ignatova, S. Role of Countercurrent Chromatography in modernisation of Chinese herbal medicines, 8th World Congress of Chinese Medicine (WCCM2011), 2-3 September 2011, London, UK Arbenz, L., Bridger, J.M., Foster, H.A., van den Heuvel, R., Han, T., Sutherland, I.A. and Fisher, D. Proceedings of the 16th International Conference on Biopartitioning and Purification (BPP2011), Puerto Vallarta, Mexico, 18-22 September, 2011 (Poster) P-33 Fernando, S., Allen, L., Fisher, D. andGarrard, I. (2011) Successful monoclonal antibody purification using counter current chromatography (CCC): Finding the balance between retention of biological activity and high resolution separation. Proceedings of the 16th International Conference on Biopartitioning and Purification (BPP2011), Puerto Vallarta, Mexico, 18-22 September, 2011 (Oral presentation) O4.3 Grudzien, L., Garrard, I., Fisher, D., Madeira, L.deM. and Ma, J. (2011) Isolation of small lectin from a hydroponic culture medium using two phase systems based on a thermo separation polymer. Proceedings of the 16th International Conference on Biopartitioning and Purification (BPP2011), Puerto Vallarta, Mexico, 18-22 September, 2011 (Poster) P-21 Sutherland, I.A., Ignatova, S., Simmonds, M. And Sendker, J. (2011) Good Practice in TCMs (GPTCM): Preliminary results on the quality of botanical origin, processing and extraction information contained in papers on Cornus Officinalis in the last three years. The 10th Meeting of Consortium for Globilisation of Chinese Medicine (CGCM2011) Shanghai, China, August 26-28, 2011 (Poster) 266 Ignatova, S. Douillet, N., Hewitson, P., Thickitt, C., Vilminot, E., Johns, D., Freebairn, K., Sutherland, I., Edwards, N., Harris, G., Janaway, L., Wood, P., Keay, D. and Mathews, B. (2011) API Recovery from Pharmaceutical Waste Streams by High Performance Counter-current Chromatography (HPCCC) and Intermittent Counter-current Extraction (ICcE). International Symposium, Exhibit and Workshops on Preparative and Process Chromatography (PREP 2011) Boston, USA, 10-13 July, 2011 (Oral presentation) L-222 Grudzien, L., Fisher, D., Garrard, I., Archer, I., Carr, R. and Fotheringham, I. (2010) Resolution and purification of a DL-amino acid by biocatalysis in countercurrent chromatography used as a reactor–separator. 1st RSC/SCI Symposium on Continuous Processing and Flow Chemistry (Poster and Bursary Prize winner), 3-4 November 2010, GSK, Stevenage, UK Ignatova, S., Hewitson, P., Sutherland, I.A., Thickitt, C., Johns, D., Freebairn, K., Guzlek, H., Edwards, N., Wood, P., Janaway, L. and Mathews, B. (2010) New ways to solve old problems: Purification of Waste Streams, 13th Symposium on Preparative and Industrial Chromatography and Allied Techniques (SPICA2010) Stockholm, Sweden, September 12 - 15, 2010 (Abstract – Oral) Sutherland, I.A., Sieber, R., Hewitson, P., Arbenz, L., Kinkel J., van den Heuvel, R. and Fisher, D. (2010) Commercial potential of a new dynamic extraction process for proteins, 13th Symposium on Preparative and Industrial Chromatography and Allied Techniques (SPICA2010) Stockholm, Sweden, September 12 - 15, 2010 (Abstract – Oral) Van den Heuvel, R.Hewitson, P., Siebers, R., Guan, Y.H. and Sutherland, I.A. (2010) J-type toroidal countercurrent chromatography for protein separations. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Abstract – Oral) 4-1 Zhang, M., Ignatova, S., Hu, P., Liang, Q., Wang, Y., Luo, G. Wujun, F. and Sutherland, I.A. (2010) Exploiting counter-current chromatography as a green process: purification of tanshinone IIA and cryptotanshinone from Salvia miltiorrhiza Bunge as a case study. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Poster) P67 Sutherland, I.A., Ignatova, S., Hewitson, P., Janaway, L., Wood, P., Edwards, N., Guzlek, H., Keay, D., Freebairn, K., Johns, D., Langdale, N., Thickitt, C., Vilminot, E. and Mathews, B. (2010) Scalable Technology for the Extraction of Pharmaceutics (STEP): the transition from academic knowhow to industrial reality. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Abstract – Plenaryl) 1-1 Sutherland, I.A., Hewitson, P. and de Folter, J. (2010) Toroidal Coil Chromatography (TCC): the effect of scale-up and “g” field on stage efficiency. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Poster) P49 Ignatova, S., Hewitson, P. and Sutherland, I.A. (2010) Evaluation of Dual Flow Counter-current Chromatography and Intermittent Counter-current Extraction. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Poster) P15 Ignatova, S., Sumner, N., Colclough, N. and Sutherland, I.A. (2010) Gradient elution in Counter-Current Chromatography: a new layout for an old path. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Abstract – Oral) 1-5 Hewitson, P., Ignatova, S. and Sutherland, I.A. (2010) Effect of the Key Operating Parameters on the efficiency of Intermittent Counter-current Extraction. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Abstract – Oral) 4-3 Grudzien, L., Fisher, D., Garrard, I., Archer, I., Carr, R. and Fotheringham, I. (2010) Resolution and purification of a DL-amino acid by biocatalysis in countercurrent chromatography used as a reactor–separator. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Poster) P66 Fernando, S, Garrard, I , Allen, L and Fisher, D. (2010) Monoclonal antibody purification using robotic phase system selection coupled with counter current chromatography. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Poster) P61 de Folter, J. and Sutherland, I.A. (2010) Accurate Chromatogram Peak Fitting. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Poster) P6 de Folter, J. and Sutherland, I.A. (2010) Counter-current chromatography units model. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Poster) P1 de Folter, J. and Sutherland, I.A. (2010) Modelling advanced Counter-Current Chromatography modes. Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Abstract - Oral) 5-2 Audo, G., Couillard, F., Fisher, D. and Sutherland, I. (2010) Continuous purification of proteins using True Moving Bed CPC/CCC system, Proceedings of the 6th International Symposium on Countercurrent Chromatography (CCC2010), Lyon, France, July 28-30, 2010, (Poster) P9 Sutherland, I.A. (2010) Scalable technology for the extraction of pharmaceuticals (STEP) World Biopharm Forum 2010: Cancer Biologics and Therapy, 28-29 June 2010, Robinson College, Cambridge, UK (Oral Presentation) Sutherland, I.A. and Freebairn, K. (2010) Scalable technology for the extraction of pharmaceuticals (STEP), Pharmaceutical Manufacturing Survival in the 21st Century, Institution of Mechanical Engineers, 12 May, 2010 (Oral Presentation) Fernando, S., Garrard, I., Allen, L. and Fisher, D. (2009) Monoclonal antibody purification using robotic phase systems election coupled with counter current chromatography, Bioprocessing UK, York, Nov 2009 (Poster, bursary prize winner) Fisher, D. and Sutherland, I.A. (2009) CCC and Chinese herbal medicines, Workshop at Brunel as part of the 8th Consortium Meeting for the Globalisation of Chinese Medicine, August 26-28, 2009 (Oral Presentation) Fisher, D. (2009) Scalable technology for the extraction of active principles from Chinese herbal medicines, at "TCM in Tomorrow’s World" Cambridge University as part of the 8th Consortium Meeting for the Globalisation of Chinese Medicine, August 26-28, 2009 Nottingham, UK (Oral Presentation) Sutherland, I.A. (2009) The UK Consortium for the Globalisation of Chinese Medicines, 8th Consortium Meeting for the Globalisation of Chinese Medicine, August 26-28, 2009, Nottingham, UK (Oral Presentation) Garrard, I and Fisher, D. (2009) High Capacity CCC for fast isolation of Natural Products, Royal Society of Chemistry Conference "Functional Molecules from Natural Sources", 6-8 July, 2009, Oxford, UK Siebers, R., Guan, Y.H., Fisher, D. and Sutherland, I.A. (2009) Protein Separation using Detergent-based Aqueous Two-Phase Systems on Counter-Current Chromatography. Proceedings of the 15th International Conference on Biopartitioning and Purification (BPP2009), Brunel University, Uxbridge, UK, 14-19 June, 2009, (Poster) P-21 Rubio, N., Ignatova, S., Sutherland, I.A. and Minguillon, C. (2009) Multiple Dual-Mode Counter-Current Chromatography Applied to Chiral Separations. Proceedings of the 15th International Conference on Biopartitioning and Purification (BPP2009), Brunel University, Uxbridge, UK, 14-19 June, 2009, (Poster) P-32 Hawes, D., Ignatova, S., van den Heuvel, R. and Sutherland, I.A. (2009) Non-Synchronous Preparative CCC – the Next Generation Countercurrent Centrifuge where Phase Separation and Mixing can be Independently Controlled. Proceedings of the 15th International Conference on Biopartitioning and Purification (BPP2009), Brunel University, Uxbridge, UK, 14-19 June, 2009, (Abstract – Oral) O31 Grudzien, L., Garrard,I, van den Heuvel, E., Archer, I., Carr, R, Fotheringham, I and Fisher, D (2009( Resolution and Purification of a DL-amino acid by Biocatalyisi in ATPS in a Reactor-Separator Proceedings of the 15th International Conference on Biopartitioning and Purification (BPP2009), Brunel University, Uxbridge, UK, 14-19 June, 2009, (Abstract-Oral) O-32) Guan, Y.H., Fisher, D., Sutherland, I.A. and Siebers, R. (2009) Protein Separation Using Toroidal Columns by Type-J Synchronous Counter-Current Chromatography: Scaling Up by Increasing the Bore Size. Proceedings of the 15th International Conference on Biopartitioning and Purification (BPP2009), Brunel University, Uxbridge, UK, 14-19 June, 2009, (Poster) P-23 Fernando, S., Garrard, I., Allen, L. and Fisher, D. (2009) Monoclonal antibody purification using robotic phase system selection coupled with counter current chromatography, Proceedings of the 15th International Conference on Biopartitioning and Purification (BPP2009), Brunel University, Uxbridge, UK, 14-19 June, 2009, (Poster) P-11 Bourton, E., Guan, Y.H., Sutherland, I.A. and Fisher, D. (2009) Application led column design for protein separations in ATPS by countercurrent chromatography. Proceedings of the 15th International Conference on Biopartitioning and Purification (BPP2009), Brunel University, Uxbridge, UK, 14-19 June, 2009, (Poster) P-22 Fisher, D. (2008) High-throughput Fractionation of TCM by Countercurrent Chromatography (CCC), China Week, August 1, 2008 (Oral Presentation) Royal Society of Medicine, London, UK Ye, H., Ignatova, S., Chen, L. and Sutherland, I.A. (2008) Optimising resolution for a preparative separation of Chinese herbal medicine using a surrogate model sample system. (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Poster) PO-27 Hawes, D., Ignatova, S., van den Heuvel, R. and Sutherland, I.A. (2008) Non-Synchronous Preparative CCC - the Next Generation Countercurrent Centrifuge where Phase Separation and Mixing can be Independently Controlled. (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Poster) PO-09 Hewitson, P., Ignatova, S., Ye, H., Chen, L. and Sutherland, I.A. (2008) Intermittent Counter-current Extraction as an Alternative Approach to Purification of Chinese Herbal Medicine. (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Poster) PO-08 de Folter, J., Sutherland, I.A. and Cribbin, T. (2008) Introducing interactive visualisation to counter-current chromatography modelling (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Poster) PO-07 van den Heuvel, R. and Sutherland, I.A. (2008) Phase Distribution Visualisation in Continuous Counter-Current Extraction (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Poster) PO-06 Konig, C.S. and Sutherland, I.A. (2008) Numerical Modelling of Liquid-Liquid Flow in Central Partition Chromatography (CPC) Columns. (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Poster) PO-01 van den Heuvel, R., Mathews, B., Dubant, S. and Sutherland, I.A. (2008) Feasibility Study of Continuous Counter-Current Extraction on an Industrial Sample (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Oral Presentation) OR-39 Guan, Y.H., Hewitson, P., Fisher, D. and Sutherland, I.A. (2008) Scalable Protein Separation using Aqueous Two Phase Systems on J-Type Countercurrent Chromatography with Toroidal Columns. (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Oral Presentation) OR-38 Hewitson, P., Ignatova, S. and Sutherland, I.A. (2008) An 18 Litre Process Scale High Performance Counter-Current Chromatography Centrifuge (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Oral Presentation) OR-37 Sutherland, I.A. and Fisher, D. (2008) The Role of Counter-Current Chromatography in the Modernisation of Traditional Chinese Medicines (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Oral Presentation) OR-25 Ignatova, S. and Hewitson, P. (2008) Establishing the Key Operating Parameters for Continuous Counter-current Extraction. (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Oral Presentation) OR-7 de Folter, J. and Sutherland, I.A. (2008) Advanced modelling of counter-current chromatography with variable phase distribution and movement. Proceedings of the 5th International Conference on Countercurrent Chromatography (CCC2008), Rio de Janeiro, Brazil, July 26-29, 2008, (Oral Presentation) OR-6