Professor Arturo Sala
Professor
Heinz Wolff 123A
- Email: arturo.sala@brunel.ac.uk
- Tel: +44 (0)1895 265547
Bibbò, S., Capone, E., Lovato, G., Lamolinara, A., Ponziani, S., Iezzi, M., et al. (2024) 'EV20/Omomyc: A novel dual MYC/HER3 targeting immunoconjugate'. Journal of Controlled Release, 374. pp. 171 - 180. ISSN: 0168-3659 Open Access Link
Cicirò, Y., Ragusa, D. and Sala, A. (2024) 'Expression of the checkpoint kinase BUB1 is a predictor of response to cancer therapies'. Scientific Reports, 14 (1). pp. 1 - 15. ISSN: 2045-2322 Open Access Link
Cicirò, Y., Ragusa, D., Tejera Nevado, P., Lattanzio, R., Sala, G., DesRochers, T., et al. (2023) 'The mitotic checkpoint kinase BUB1 is a direct and actionable target of MYB in adenoid cystic carcinoma'. FEBS Letters, 598 (2). pp. 252 - 265. ISSN: 0014-5793 Open Access Link
Tsakaneli, A., Carregari, VC., Morini, M., Eva, A., Cangemi, G., Chayka, O., et al. (2022) 'MYC regulates metabolism through vesicular transfer of glycolytic kinases'. Open Biology, 11 (12). pp. 1 - 15. ISSN: 2046-2441 Open Access Link
Tagalakis, AD., Jayarajan, V., Maeshima, R., Ho, KH., Syed, F., Wu, L-P., et al. (2021) 'Integrin-Targeted, Short Interfering RNA Nanocomplexes for Neuroblastoma Tumor-Specific Delivery Achieve MYCN Silencing with Improved Survival'. Advanced Functional Materials, 31 (37). pp. 1 - 12. ISSN: 1616-301X Open Access Link
Cicirò, Y. and Sala, A. (2021) 'MYB oncoproteins: emerging players and potential therapeutic targets in human cancer'. Oncogenesis, 10 (2). pp. 1 - 15. ISSN: 2157-9024 Open Access Link
Capone, E., Lamolinara, A., Pastorino, F., Gentile, R., Ponziani, S., Di Vittorio, G., et al. (2020) 'Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma'. Cancers, 12 (10). pp. 1 - 18. ISSN: 2072-6694 Open Access Link
Andersson, MK., Mangiapane, G., Nevado, PT., Tsakaneli, A., Carlsson, T., Corda, G., et al. (2020) 'ATR is a MYB regulated gene and potential therapeutic target in adenoid cystic carcinoma'. Oncogenesis, 9 (1). pp. 5. ISSN: 2157-9024 Open Access Link
Karteris, E., Nieddu, V., Piredda, R., Bexel, D., Barton, J., Anderson, J., et al. (2019) 'Engineered human mesenchymal stem cells for neuroblastoma therapeutics'. Oncology Reports, 42 (1). pp. 1 - 8. ISSN: 1021-335X Open Access Link
Capone, E., Piccolo, E., Fichera, I., Ciufici, P., Barcaroli, D., Sala, A., et al. (2017) 'Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma.'. Oncotarget, 8 (36). pp. 60368 - 60377. ISSN: 1949-2553
Sala, A. (2017) 'Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma'. Oncotarget, 8 (36). pp. 60368 - 60377. ISSN: 1949-2553 Open Access Link
Sala, A. and corda, G. (2017) 'Non-canonical WNT/PCP signalling in cancer: Fzd6 takes centre stage.'. Oncogenesis, 6 (7). pp. e364. ISSN: 2157-9024 Open Access Link
Corda, G., Sala, G., Lattanzio, R., Iezzi, M., Sallese, M., Fragassi, G., et al. (2016) 'Functional and prognostic significance of the genomic amplification of frizzled receptor 6 ( FZD6 ) in breast cancer'. The Journal of Pathology, 241 (3). pp. 350 - 361. ISSN: 0022-3417 Open Access Link
Corda, G. and Sala, A. (2016) 'Cutaneous cylindroma: it's all about MYB'. The Journal of Pathology, 29 (4). pp. 391 - 393. ISSN: 0022-3417 Open Access Link
Dvorkina, M., Nieddu, V., Chakelam, S., Pezzolo, A., Cantilena, S., Leite, AP., et al. (2016) 'A promyelocytic leukemia protein-thrombospondin 2 axis and the risk of relapse in neuroblastoma.'. Clinical cancer research : an official journal of the American Association for Cancer Research, 22 (13). pp. 3398 - 3409. ISSN: 1078-0432 Open Access Link
Sala, A. (2015) 'Editorial: Targeting MYCN in pediatric cancers'. Frontiers in Oncology, 5 (MAY). pp. 1 - 2. ISSN: 2234-943X Open Access Link
Chayka, O., D'Acunto, CW., Middleton, O., Arab, M. and Sala, A. (2014) 'Identification and pharmacological inactivation of the MYCN gene network as a therapeutic strategy for neuroblastic tumor cells'. Journal of Biological Chemistry, 290 (4). pp. 2198 - 2212. ISSN: 0021-9258 Open Access Link
Santilli, G., Anderson, J., Thrasher, AJ. and Sala, A. (2013) 'Catechins and antitumor immunity: Not MDSC's cup of tea'. OncoImmunology, 2 (6). pp. e24443 - e24443. ISSN: 2162-4011
Corvetta, D., Chayka, O., Gherardi, S., D'Acunto, CW., Cantilena, S., Valli, E., et al. (2013) 'Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: Functional and therapeutic implications'. Journal of Biological Chemistry, 288 (12). pp. 8332 - 8341. ISSN: 0021-9258 Open Access Link
Santilli, G., Thrasher, AJ., Piotrowska, I., Cantilena, S., Chayka, O., D'Alicarnasso, M., et al. (2013) 'Polyphenon E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells'. Clinical Cancer Research, 19 (5). pp. 1116 - 1125. ISSN: 1078-0432 Open Access Link
Sala, A. (2012) 'c-MYB and TGF-β: EMT's dynamic duo in breast cancer'. Cell Cycle, 11 (1). pp. 17. ISSN: 1538-4101
Sottile, F., Gnemmi, I., Cantilena, S., D'Acunto, WC. and Sala, A. (2012) 'A chemical screen identifies the chemotherapeutic drug topotecan as a specific inhibitor of the B-MYB/MYCN axis in neuroblastoma'. Oncotarget, 3 (5). pp. 535 - 545. ISSN: 1949-2553 Open Access Link
Cantilena, S., Pastorino, F., Pezzolo, A., Chayka, O., Pistoia, V., Ponzoni, M. and et al. (2011) 'Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas'. Oncotarget, 2 (12). pp. 976 - 983. ISSN: 1949-2553 Open Access Link
Chaiwatanasirikul, K-A. and Sala, A. (2011) 'The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60'. Cell Death and Disease, 2 (10). ISSN: 2041-4889
Chaiwatanasirikul, KA. and Sala, A. (2011) 'The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60'. Cell Death and Disease. ISSN: 2041-4889 Open Access Link
Gualdrini, F., Corvetta, D., Cantilena, S., Chayka, O., Tanno, B., Raschellà, G. and et al. (2010) 'Addiction of MYCN amplified tumours to B-MYB underscores a reciprocal regulatory loop'. Oncotarget, 1 (4). pp. 278 - 288. ISSN: 1949-2553
Bettuzzi, S., Davalli, P., Davoli, S., Chayka, O., Rizzi, F., Belloni, L., et al. (2009) 'Genetic inactivation of ApoJ/clusterin: Effects on prostate tumourigenesis and metastatic spread'. Oncogene, 28 (49). pp. 4344 - 4352. ISSN: 0950-9232
Sala, A., Bettuzzi, S., Pucci, S., Chayka, O., Dews, M. and Thomas-Tikhonenko, A. (2009) 'Regulation of CLU gene expression by oncogenes and epigenetic factors implications for tumorigenesis'. Advances in Cancer Research, 105 (1). pp. 115 - 132. ISSN: 0065-230X
Chayka, O., Corvetta, D., Dews, M., Caccamo, AE., Piotrowska, I., Santilli, G., et al. (2009) 'Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas'. Journal of the National Cancer Institute, 101 (9). pp. 663 - 677. ISSN: 0027-8874 Open Access Link
Schwab, R., Bussolari, R., Corvetta, D., Chayka, O., Santilli, G., Kwok, JM., et al. (2008) 'Isolation and functional assessment of common, polymorphic variants of the B-MYB proto-oncogene associated with a reduced cancer risk'. Oncogene, 27 (20). pp. 2929 - 2933. ISSN: 0950-9232
Schwab, R., Caccamo, A., Bettuzzi, S., Anderson, J. and Sala, A. (2007) 'B-MYB is hypophosphorylated and resistant to degradation in neuroblastoma: Implications for cell survival'. Blood Cells, Molecules, and Diseases, 39 (3). pp. 263 - 271. ISSN: 1079-9796
Santilli, G., Aronow, BJ. and Sala, A. (2003) 'Essential requirement of apolipoprotein J (clusterin) signaling for IkappaB expression and regulation of NF-kappaB activity'. Journal of Biological Chemistry, 278 (40). pp. 38214 - 38219. ISSN: 0021-9258