Dr Cristina Correia Antunes Pina
Senior Lecturer in Biomedical Sciences
Heinz Wolff 229
- Email: cristina.pina@brunel.ac.uk
- Tel: +44 (0)1895 266676
Pina, C. (2024) 'Contributions of transcriptional noise to leukaemia evolution: KAT2A as a case-study'. Philosophical Transactions of the Royal Society B: Biological Sciences, 379 (1900). pp. 1 - 11. ISSN: 0962-8436 Open Access Link
Dijkhuis, L., Johns, A., Ragusa, D., van den Brink, S. and Pina, C. (2023) 'Haematopoietic development and HSC formation in vitro: promise and limitations of gastruloid models'. Emerging Topics in Life Sciences, 7 (4). pp. 439 - 454. ISSN: 2397-8554 Open Access Link
Ragusa, D., Suen, C-W., Torregrosa Cortes, G., Dijkhuis, L., Byrne, C., Ionescu, G-A., et al. (2022) 'Dissecting infant leukemia developmental origins with a hemogenic gastruloid model'. biorXiv. pp. 1 - 43.Open Access Link
Ragusa, D., Cicirò, Y., Federico, C., Saccone, S., Bruno, F., Saeedi, R., et al. (2022) 'Engineered model of t(7;12)(q36;p13) AML recapitulates patient-specific features and gene expression profiles'. Oncogenesis, 11 (1). pp. 1 - 7. ISSN: 2157-9024 Open Access Link
Gupta, S., Dovey, OM., Domingues, AF., Cyran, OW., Cash, CM., Giotopoulos, G., et al. (2022) 'Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis'. Science advances, 8 (31). pp. 1 - 15. ISSN: 2375-2548 Open Access Link
Arede, L., Foerner, E., Wind, S., Kulkarni, R., Domingues, AF., Giotopoulos, G., et al. (2021) 'KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia'. Blood advances, 6 (1). pp. 165 - 180. ISSN: 2473-9529 Open Access Link
Arede, L. and Pina, C. (2020) 'Buffering noise: KAT2A modular contributions to stabilization of transcription and cell identity in cancer and development'. Experimental Hematology, 93. pp. 25 - 37. ISSN: 0301-472X Open Access Link
Domingues, AF., Kulkarni, R., Giotopoulos, G., Gupta, S., Vinnenberg, L., Arede, L., et al. (2020) 'Loss of Kat2a Enhances Transcriptional Noise and depletes Acute Myeloid Leukaemia Stem-like Cells'. eLife, 9. pp. 1 - 29. ISSN: 2050-084X Open Access Link
Moris, N., Edri, S., Seyres, D., Kulkarni, R., Domingues, AF., Balayo, T., et al. (2018) 'Histone Acetyltransferase KAT2A Stabilizes Pluripotency with Control of Transcriptional Heterogeneity'. Stem Cells, 36 (12). pp. 1828 - 1838. ISSN: 1066-5099 Open Access Link
Tzelepis, K., Koike-Yusa, H., De Braekeleer, E., Li, Y., Metzakopian, E., Dovey, OM., et al. (2016) 'A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia'. Cell Reports, 17 (4). pp. 1193 - 1205. ISSN: 2211-1247 Open Access Link
Moris, N., Pina, C. and Arias, AM. (2016) 'Transition states and cell fate decisions in epigenetic landscapes'. Nature Reviews Genetics, 17 (11). pp. 693 - 703. ISSN: 1471-0056
Pina, C., Teles, J., Fugazza, C., May, G., Wang, D., Guo, Y., et al. (2015) 'Single-Cell Network Analysis Identifies DDIT3 as a Nodal Lineage Regulator in Hematopoiesis'. Cell Reports, 11 (10). pp. 1503 - 1510. ISSN: 2211-1247
Pina, C., Fugazza, C., Tipping, AJ., Brown, J., Soneji, S., Teles, J., et al. (2012) 'Inferring rules of lineage commitment in haematopoiesis'. Nature Cell Biology, 14 (3). pp. 287 - 294. ISSN: 1465-7392