Dr Edwin Routledge
Honorary Reader
Heinz Wolff 001A
- Email: edwin.routledge@brunel.ac.uk
- Tel: +44 (0)1895 266299
- Environmental Sciences
- Department of Life Sciences
- College of Health, Medicine and Life Sciences
Imiuwa, M., Baynes, A., Kanda, R. and Routledge, E. (2024) 'Environmentally relevant concentrations of the tricyclic antidepressant, amitriptyline, affect feeding and reproduction in a freshwater mollusc'. Ecotoxicology and Environmental Safety, 281. pp. 1 - 12. ISSN: 0147-6513 Open Access Link
Imiuwa, ME., Baynes, A. and Routledge, EJ. (2023) 'Understanding target-specific effects of antidepressant drug pollution on molluscs: A systematic review protocol'. PLOS ONE, 18 (6). pp. 1 - 13. ISSN: 1932-6203 Open Access Link
Lynch, AE., Noble, LR., Jones, CS. and Routledge, EJ. (2022) 'Common Aquatic Pollutants Modify Hemocyte Immune Responses in Biomphalaria glabrata'. Frontiers in Immunology, 13. pp. 1 - 15. ISSN: 1664-3224 Open Access Link
Wang, Y., Baynes, A., Renner, KO., Zhang, M., Scrimshaw, MD. and Routledge, EJ. (2022) 'Uptake, Elimination and Effects of Cosmetic Microbeads on the Freshwater Gastropod Biomphalaria glabrata'. Toxics, 10 (2). pp. 1 - 13. ISSN: 2305-6304 Open Access Link
Renner, KO., Foster, HA., Routledge, EJ. and Scrimshaw, MD. (2021) 'A Comparison of Different Approaches for Characterizing Microplastics in Selected Personal Care Products'. Environmental Toxicology and Chemistry, 41 (4). pp. 880 - 887. ISSN: 0730-7268 Open Access Link
Lawton, E., Antczak, P., Walker, S., Germain-Cripps, E., Falciani, F. and Routledge, EJ. (2021) 'An investigation into the biological effects of indirect potable reuse water using zebrafish embryos'. Science of the Total Environment, 789. pp. 1 - 13. ISSN: 0048-9697 Open Access Link
Nilsson, C. (2020) 'Retinoids in Mammalian Reproduction, with an Initial Scoping Effort to Identify Regulatory Methods'. Place of publication: Nordisk Ministerråd. Available at: https://norden.diva-portal.org/smash/record.jsf?pid=diva2%3A1424722&dswid=-8260. ISSN: 0908-6692 Open Access Link
Baynes, A., Pino, GM., Duong, GH., Lockyer, AE., McDougall, C., Jobling, S. and et al. (2019) 'Early embryonic exposure of freshwater gastropods to pharmaceutical 5α-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell'. Scientific Reports, 9 (1). pp. 1 - 12. ISSN: 2045-2322 Open Access Link
Peter, A. and Routledge, EJ. (2018) 'Present-day monitoring underestimates the risk of exposure to pathogenic bacteria from cold water storage tanks'. PLoS ONE, 13 (4). pp. 1 - 21. ISSN: 1932-6203 Open Access Link
Hettwer, K., Jähne, M., Frost, K., Giersberg, M., Kunze, G., Trimborn, M., et al. (2017) 'Validation of Arxula Yeast Estrogen Screen assay for detection of estrogenic activity in water samples: Results of an international interlaboratory study'. Science of the Total Environment, 621. pp. 612 - 625. ISSN: 0048-9697 Open Access Link
Adema, CM., Hillier, LW., Jones, CS., Loker, ES., Knight, M., Minx, P., et al. (2017) 'Whole genome analysis of a schistosomiasis-transmitting freshwater snail (vol 8, 15451, 2017)'. NATURE COMMUNICATIONS, 8 (1). pp. 16153. ISSN: 2041-1723 Open Access Link
Routledge, EJ., Peter, A. and Thompson, C. (2017) 'Barriers to Effective Legionella Control in a Changing World - A Practitioners View'. Environmental Technology Reviews, 6 (1). pp. 144 - 155. ISSN: 2162-2515 Open Access Link
Adema, CM., Hillier, LW., Jones, CS., Loker, ES., Knight, M., Minx, P., et al. (2017) 'Whole genome analysis of a schistosomiasis-transmitting freshwater snail'. NATURE COMMUNICATIONS, 8 (1). pp. 15451. ISSN: 2041-1723 Open Access Link
Cossali, G., Routledge, EJ., Ratcliffe, MS., Blakes, H., Fielder, JE. and Karayiannis, TG. (2016) 'Inactivation of E-coli, Legionella, and Pseudomonas in Tap Water Using Electrochemical Disinfection'. JOURNAL OF ENVIRONMENTAL ENGINEERING, 142 (12). ISSN: 0733-9372 Open Access Link
Kaur, S., Baynes, A., Lockyer, AE., Routledge, EJ., Jones, CS., Noble, LR. and et al. (2016) 'Steroid Androgen Exposure during Development Has No Effect on Reproductive Physiology of Biomphalaria glabrata'. PLOS ONE, 11 (7). pp. e0159852 - e0159852. ISSN: 1932-6203 Open Access Link
Kaur, S., Jobling, S., Jones, CS., Noble, LR., Routledge, EJ. and Lockyer, AE. (2015) 'The Nuclear Receptors of Biomphalaria glabrata and Lottia gigantea: Implications for Developing New Model Organisms'. PLOS ONE, 10 (4). pp. e0121259 - e0121259. ISSN: 1932-6203 Open Access Link
Lynch, AE., Triajianto, J. and Routledge, E. (2014) 'Low-Cost Motility Tracking System (LOCOMOTIS) for time-lapse microscopy applications and cell visualisation'. PLoS ONE, 9 (8). pp. e103547 - e103547. ISSN: 1932-6203 Open Access Link
Julis, J., Bartlett, SA., Baader, S., Beresford, N., Routledge, EJ., Cazin, CSJ. and et al. (2014) 'Selective ethenolysis and oestrogenicity of compounds from cashew nut shell liquid'. GREEN CHEMISTRY, 16 (5). pp. 2846 - 2856. ISSN: 1463-9262
Bannister, R., Beresford, N., Granger, DW., Pounds, NA., Rand-Weaver, M., White, R., et al. (2013) 'No substantial changes in estrogen receptor and estrogen-related receptor orthologue gene transcription in Marisa cornuarietis exposed to estrogenic chemicals'. Aquatic Toxicology, 140. pp. 19 - 26. ISSN: 0166-445X Open Access Link
Orton, F. and Routledge, E. (2011) 'Agricultural intensity in ovo affects growth, metamorphic development and sexual differentiation in the Common toad (Bufo bufo)'. Ecotoxicology, 20 (4). pp. 901 - 911. ISSN: 0963-9292
Benstead, RS., Baynes, A., Casey, D., Routledge, EJ. and Jobling, S. (2011) '17 beta-Oestradiol may prolong reproduction in seasonally breeding freshwater gastropod molluscs'. AQUATIC TOXICOLOGY, 101 (2). pp. 326 - 334. ISSN: 0166-445X
Orton, F., Lutz, I., Kloas, W. and Routledge, EJ. (2009) 'Endocrine Disrupting Effects of Herbicides and Pentachlorophenol: In Vitro and in Vivo Evidence'. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 43 (6). pp. 2144 - 2150. ISSN: 0013-936X
Clarke, N., Routledge, EJ., Garner, A., Casey, D., Benstead, R., Walker, D., et al. (2009) 'Exposure to Treated Sewage Effluent Disrupts Reproduction and Development in the Seasonally Breeding Ramshorn Snail (Subclass: Pulmonata, Planorbarius corneus)'. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 43 (6). pp. 2092 - 2098. ISSN: 0013-936X Open Access Link
Gabriel, FLP., Routledge, EJ., Heidlberger, A., Rentsch, D., Guenther, K., Giger, W., et al. (2008) 'Isomer-specific degradation and endocrine disrupting activity of nonylphenols'. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 42 (17). pp. 6399 - 6408. ISSN: 0013-936X
Tempest, HG., Homa, ST., Routledge, EJ., Garner, A., Zhai, X-P. and Griffin, DK. (2008) 'Plants Used in Chinese Medicine for the Treatment of Male Infertility Possess Antioxidant and Anti-Oestrogenic Activity'. SYSTEMS BIOLOGY IN REPRODUCTIVE MEDICINE, 54 (4-5). pp. 185 - 195. ISSN: 1939-6368
Harris, CA., Routledge, EJ., Schaffner, C., Brian, JV., Giger, W. and Sumpter, JP. (2007) 'Benzotriazole is antiestrogenic in vitro but not in vivo'. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 26 (11). pp. 2367 - 2372. ISSN: 0730-7268 Open Access Link
Bannister, R., Beresford, N., May, D., Routledge, EJ., Jobling, S. and Rand-Weaver, M. (2007) 'Novel estrogen receptor-related transcripts in Marisa cornuarietis; a freshwater snail with reported sensitivity to estrogenic chemicals'. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 41 (7). pp. 2643 - 2650. ISSN: 0013-936X
Coleman, HM., Routledge, EJ., Sumpter, JP., Eggins, BR. and Byrne, JA. (2004) 'Rapid loss of estrogenicity of steroid estrogens by UVA photolysis and photocatalysis over an immobilised titanium dioxide catalyst'. WATER RESEARCH, 38 (14-15). pp. 3233 - 3240. ISSN: 0043-1354
Routledge, EJ. (2003) 'Identifying the causative agents: The use of combined chemical and biological strategies in monitoring programs'.Symposium on Implications of Endocrine Active Substances for Humans and Wildlife. YOKOHAMA, JAPAN. 1 - 21 November. Walter de Gruyter GmbH. pp. 2461 - 2466. ISSN: 0033-4545
Sheahan, DA., Brighty, GC., Daniel, M., Kirby, SJ., Hurst, MR., Kennedy, J., et al. (2002) 'Estrogenic activity measured in a sewage treatment works treating industrial inputs containing high concentrations of alkylphenolic compounds - A case study'. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 21 (3). pp. 507 - 514. ISSN: 0730-7268
Sheahan, DA., Brighty, GC., Daniel, M., Jobling, S., Harries, JE., Hurst, MR., et al. (2002) 'Reduction in the estrogenic activity of a treated sewage effluent discharge to an English river as a result of a decrease in the concentration of industrially derived surfactants'. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 21 (3). pp. 515 - 519. ISSN: 0730-7268
Routledge, EJ., White, R., Parker, MG. and Sumpter, JP. (2000) 'Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) alpha and ER beta'. JOURNAL OF BIOLOGICAL CHEMISTRY, 275 (46). pp. 35986 - 35993. ISSN: 0021-9258
Schmieder, PK., Aptula, AO., Routledge, EJ., Sumpter, JP. and Mekenyan, OG. (2000) 'Estrogenicity of alkylphenolic compounds: A 3-D structure-activity evaluation of gene activation'. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 19 (7). pp. 1727 - 1740. ISSN: 0730-7268
Beresford, N., Routledge, EJ., Harris, CA. and Sumpter, JP. (2000) 'Issues arising when interpreting results from an in vitro assay for estrogenic activity'. TOXICOLOGY AND APPLIED PHARMACOLOGY, 162 (1). pp. 22 - 33. ISSN: 0041-008X Open Access Link
Routledge, EJ., Waldock, M. and Sumpter, JP. (1999) 'Response to comment on “Identification of estrogenic chemicals in STW effluent. 1. Chemical fractionation and in vitro biological screening”'. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 33 (2). pp. 371 - 371. ISSN: 0013-936X
Johnson, AC., L Williams, R., Ulahannan, T., Routledge, EJ., Waldock, M. and Sumpter, JP. (1999) 'Comment on 'identification of estrogenic chemicals in STW effluent. 1. Chemical fractionation and in vitro biological screening' [2] (multiple letters)'. Environmental Science and Technology, 33 (2). pp. 369 - 370. ISSN: 0013-936X
Routledge, EJ., Parker, J., Odum, J., Ashby, J. and Sumpter, JP. (1998) 'Some alkyl hydroxy benzoate preservatives (parabens) are estrogenic'. TOXICOLOGY AND APPLIED PHARMACOLOGY, 153 (1). pp. 12 - 19. ISSN: 0041-008X
Tyler, CR. and Routledge, EJ. (1998) 'Oestrogenic effects in fish in English rivers with evidence of their causation'. PURE AND APPLIED CHEMISTRY, 70 (9). pp. 1795 - 1804. ISSN: 0033-4545
Routledge, EJ., Sheahan, D., Desbrow, C., Brighty, GC., Waldock, M. and Sumpter, JP. (1998) 'Identification of estrogenic chemicals in STW effluent. 2. In vivo responses in trout and roach'. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 32 (11). pp. 1559 - 1565. ISSN: 0013-936X
Desbrow, C., Routledge, EJ., Brighty, GC., Sumpter, JP. and Waldock, M. (1998) 'Identification of estrogenic chemicals in STW effluent. 1. Chemical fractionation and in vitro biological screening'. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 32 (11). pp. 1549 - 1558. ISSN: 0013-936X
Ramamoorthy, K., Wang, F., Chen, IC., Safe, S., Norris, JD., McDonnell, DP., et al. (1998) 'Potency of combined estrogenic pesticides: Synergy between synthetic oestrogens?'. Chemtracts, 11 (4). pp. 306 - 308. ISSN: 1431-9268
Odum, J., Lefevre, PA., Tittensor, S., Paton, D., Routledge, EJ., Beresford, NA., et al. (1997) 'The rodent uterotrophic assay: Critical protocol features, studies with nonyl phenols, and comparison with a yeast estrogenicity assay'. REGULATORY TOXICOLOGY AND PHARMACOLOGY, 25 (2). pp. 176 - 188. ISSN: 0273-2300 Open Access Link
Routledge, EJ. and Sumpter, JP. (1997) 'Structural features of alkylphenolic chemicals associated with estrogenic activity'. JOURNAL OF BIOLOGICAL CHEMISTRY, 272 (6). pp. 3280 - 3288. ISSN: 0021-9258 Open Access Link
Ashby, J., Lefevre, PA., Odum, J., Harris, CA., Routledge, EJ. and Sumpter, JP. (1997) 'Synergy between synthetic oestrogens?'. NATURE, 385 (6616). pp. 494 - 494. ISSN: 0028-0836
Harries, JE., Sheahan, DA., Jobling, S., Matthiessen, P., Neall, P., Routledge, EJ., et al. (1996) 'A survey of estrogenic activity in United Kingdom inland waters'. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 15 (11). pp. 1993 - 2002. ISSN: 0730-7268
Routledge, EJ. and Sumpter, JP. (1996) 'Estrogenic activity of surfactants and some of their degradation products assessed using a recombinant yeast screen'. ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 15 (3). pp. 241 - 248. ISSN: 0730-7268
SHORE, RF., MYHILL, DG., ROUTLEDGE, EJ. and WILBY, A. (1995) 'IMPACT OF AN ENVIRONMENTALLY-REALISTIC INTAKE OF CADMIUM ON CALCIUM, MAGNESIUM, AND PHOSPHATE-METABOLISM IN BANK VOLES, CLETHRIONOMYS-GLAREOLUS'. ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 29 (2). pp. 180 - 186. ISSN: 0090-4341