A human IPS cell model for gene therapy vector safety evaluation
Funder: National Centre for the Replacement, Refinement and Reduction of Animals in ResearchDuration: January 2017 - December 2019
Gene therapy genotoxicity project
People
Name | Telephone | Office | ||
---|---|---|---|---|
Professor Michael Themis Professor - Gene Therapy and Genotoxicity (Principal investigator)
T: +44 (0)1895 267252
E: michael.themis@brunel.ac.uk |
+44 (0)1895 267252 | michael.themis@brunel.ac.uk | Heinz Wolff 235 |
Outputs
Themis, M., Al-Haque, S., Wang, W., Strobel-Freidekind, O., Deichmann, A., Henkaerts, E., et al. (2021) 'Application of InGetox to assess the genotoxicity of LV and AAV vectors'.ASGCT, 23rd Annual Mee9ng. Virtual. 1 - 14 May. Human Gene Therapy. pp. A136 - A136. ISSN: 1043-0342 Open Access Link
Suleman, S., Payne, A., Bowden, J., Al Haque, S., Zhan, M., Fawaz, S., et al. (2021) 'Lentivirus tethering to the genome is associated with transcription factor binding sites that favour virus survival'.ESGCT Collaborative Virtual Congress. Virtual. 1 - 22 October. Human Gene Therapy. pp. A138 - A139. ISSN: 1043-0342 Open Access Link