Dr Thomas Hofken
Senior Lecturer
Heinz Wolff 113b
- Email: thomas.hofken@brunel.ac.uk
- Tel: +44 (0)1895 267847
Joshua, I., Lin, M., Mardjuki, A., Mazzola, A. and Hoefken, T. (2023) 'A protein-protein interaction analysis suggests a wide range of new functions for the p21-activated kinase (PAK) Ste20'. International Journal of Molecular Sciences, 24 (21). pp. 1 - 31. ISSN: 1661-6596 Open Access Link
Hoefken, T. and Joshua, I. (2019) 'Ste20 and Cla4 modulate the expression of the glycerol biosynthesis enzyme Gpd1 by a novel MAPK-independent pathway'. Biochemical and Biophysical Research Communications, 517 (4). pp. 611 - 616. ISSN: 0006-291X Open Access Link
Hoefken, T. (2017) 'Ecm22 and Upc2 regulate yeast mating through control of expression of the mating genes PRM1 and PRM4'. Biochemical and Biophysical Research Communications, 493 (4). pp. 1485 - 1490. ISSN: 0006-291X Open Access Link
Joshua, IM. and Hoefken, T. (2017) 'From lipid homeostasis to differentiation: Old and new functions of the zinc cluster proteins Ecm22, Upc2, Sut1 and Sut2'. International Journal of Molecular Sciences, 18 (4). pp. 1 - 17. ISSN: 1661-6596 Open Access Link
Kennedy, H., Haack, TB., Hartill, V., Matakovic, L., Baumgartner, ER., Potter, H., et al. (2016) 'Sudden cardiac death due to deficiency of the mitochondrial inorganic pyrophosphatase PPA2'. The American journal of human genetics, 99 (3). pp. 674 - 682. ISSN: 0002-9297 Open Access Link
Woods, K. and Höfken, T. (2015) 'The zinc cluster proteins Upc2 and Ecm22 promote filamentation in Saccharomyces cerevisiae by sterol biosynthesis-dependent and -independent pathways.'. Mol Microbiol, 99 (3). pp. 512 - 527. ISSN: 0950-382X Open Access Link
Höfken, T. (2013) 'Candida and candidiasis', in Kishore, U. and Nayak, A. (eds.) Microbial pathogenesis: Infection and immunity. New York : Springer Science+Business Media and Landes Bioscience. pp. 82 - 114. ISBN 13: 978-1-4614-9529-1.
Blanda, C. and Höfken, T. (2013) 'Regulation of mating in the budding yeast Saccharomyces cerevisiae by the zinc cluster proteins Sut1 and Sut2'. Biochemical and Biophysical Research Communications, 438 (1). pp. 66 - 70. ISSN: 0006-291X Open Access Link
Foster, HA., Cui, M., Naveenathayalan, A., Unden, H., Schwanbeck, R. and Höfken, T. (2013) 'The zinc cluster protein Sut1 contributes to filamentation in Saccharomyces cerevisiae'. Eukaryot Cell, 12 (2). pp. 244 - 253. ISSN: 1535-9778 Open Access Link
Blanda, C. and Höfken, T. (2013) 'Regulation of mating in the budding yeast Saccharomyces cerevisiae by the zinc cluster proteins Sut1 and Sut2'. Biochemical and Biophysical Research Communications. ISSN: 0006-291X
Lin, M., Li, SC., Kane, PM. and Höfken, T. (2012) 'Regulation of vacuolar H -ATPase activity by the Cdc42 effector Ste20 in Saccharomyces cerevisiae'. Eukaryotic Cell, 11 (4). pp. 442 - 451. ISSN: 1535-9778 Open Access Link
Lin, M., Grillitsch, K., Daum, G., Just, U. and Höfken, T. (2009) 'Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in yeast Saccharomyces cerevisiae'. FEBS Journal, 276 (24). pp. 7253 - 7264. ISSN: 1742-464X Open Access Link
Lin, M., Unden, H., Jacquier, N., Schneiter, R., Just, U. and Höfken, T. (2009) 'The Cdc42 effectors Ste20, Cla4, and Skm1 down-regulate the expression of genes involved in sterol uptake by a mitogen-activated protein kinase-independent pathway'. Molecular Biology of the Cell, 20 (22). pp. 4826 - 4837. ISSN: 1939-4586 Open Access Link
Tiedje, C., Sakwa, I., Just, U. and Höfken, T. (2008) 'The Rho GDI Rdi1 regulates Rho GTPases by distinct mechanisms'. Molecular Biology of the Cell, 19 (7). pp. 2885 - 2896. ISSN: 1939-4586 Open Access Link
Tiedje, C., Holland, DG., Just, U. and Höfken, T. (2007) 'Proteins involved in sterol synthesis interact with Ste20 and regulate cell polarity'. Journal of Cell Science, 120 (20). pp. 3613 - 3624. ISSN: 0021-9533
Höfken, T. and Schiebel, E. (2004) 'Novel regulation of mitotic exit by the Cdc42 effectors Gic1 and Gic2'. Journal of Cell Biology, 164 (2). pp. 219 - 231. ISSN: 0021-9525 Open Access Link
Höfken, T. and Schiebel, E. (2002) 'A role for cell polarity proteins in mitotic exit'. EMBO Journal, 21 (18). pp. 4851 - 4862. ISSN: 0261-4189
Weber, H., Wagner, ACC., Jonas, L., Merkord, J., Hõfken, T., Nizze, H., et al. (2000) 'Heat shock response is associated with protection against acute interstitial pancreatitis in rats'. Digestive Diseases and Sciences, 45 (11). pp. 2252 - 2264. ISSN: 0163-2116
Höfken, T., Keller, N., Fleischer, F., Göke, B. and Wagner, ACC. (2000) 'Map kinase phosphatases (MKP's) are early responsive genes during induction of cerulein hyperstimulation pancreatitis'. Biochemical and Biophysical Research Communications, 276 (2). pp. 680 - 685. ISSN: 0006-291X
Pereira, G., Höfken, T., Grindlay, J., Manson, C. and Schiebel, E. (2000) 'The Bub2p spindle checkpoint links nuclear migration with mitotic exit'. Molecular Cell, 6 (1). pp. 1 - 10. ISSN: 1097-2765
Metzler, W., Höfken, T., Weber, H., Printz, H., Göke, B. and Wagner, ACC. (1999) 'Hyperthermia, inducing pancreatic heat-shock proteins, fails to prevent cerulein-induced stress kinase activation'. Pancreas, 19 (2). pp. 150 - 157. ISSN: 0885-3177
Wagner, ACC., Metzler, W., Höfken, T., Weber, H. and Göke, B. (1999) 'p38 Map kinase is expressed in pancreas and is immediately activated following Cerulein hyperstimulation'. Digestion, 60 (1). pp. 41 - 47. ISSN: 0012-2823
Höfken, T., Linder, D., Kleene, R., Göke, B. and Wagner, ACC. (1998) 'Membrane dipeptidase and glutathione are major components of pig pancreatic zymogen granules'. Experimental Cell Research, 244 (2). pp. 481 - 490. ISSN: 0014-4827