Professor Alex Blakemore
Professor in Human Genomics
Heinz Wolff 236
- Email: alex.blakemore@brunel.ac.uk
- Tel: +44 (0)1895 268430
Quinton, ND., Laird, SM., Tuckerman, EM., Cork, BA., Li, TC. and Blakemore, AIF. (2003) 'Expression of leptin receptor isoforms in vitro: Lack of effects of leptin on endometrial cytokine and MMP production'. American Journal of Reproductive Immunology, 50 (3). pp. 224 - 231. ISSN: 8755-8920
Laird, SM., Tuckerman, EM., Cork, BA., Linjawi, S., Blakemore, AIF. and Li, TC. (2003) 'A review of immune cells and molecules in women with recurrent miscarriage'. Human Reproduction Update, 9 (2). pp. 163 - 174. ISSN: 1355-4786
Quinton, N., Lee, A., Ross, R., Eastell, R. and Blakemore, A. (2001) 'A single nucleotide polymorphism (SNP) in the leptin receptor is associated with BMI, fat mass and leptin levels in postmenopausal Caucasian women'. Human Genetics, 108 (3). pp. 233 - 236. ISSN: 0340-6717
Laird, SM., Quinton, ND., Anstie, B., Li, TC. and Blakemore, AIF. (2001) 'Leptin and leptin-binding activity in women with recurrent miscarriage: Correlation with pregnancy outcome'. Human Reproduction, 16 (9). pp. 2008 - 2013. ISSN: 0268-1161
Quinton, ND., Laird, SM., Okon, MA., Li, TC., Smith, RF., Ross, RJM. and et al. (1999) 'Serum leptin levels during the menstrual cycle of healthy fertile women'. British Journal of Biomedical Science, 56 (1). pp. 16 - 19. ISSN: 0967-4845
Quinton, ND., Smith, RF., Clayton, PE., Gill, MS., Shalet, S., Justice, SK., et al. (1999) 'Leptin binding activity changes with age: The link between leptin and puberty'. Journal of Clinical Endocrinology and Metabolism, 84 (7). pp. 2336 - 2341. ISSN: 0021-972X
Maskill, JK., Laird, SM., Okon, M., Li, TC. and Blakemore, AIF. (1997) 'Stability of serum interleukin-10 levels during the menstrual cycle'. American Journal of Reproductive Immunology, 38 (5). pp. 339 - 342. ISSN: 8755-8920
Tarlow, JK., Cork, MJ., Clay, FE., Schmitt-Egenolf, M., Crane, AM., Stierle, C., et al. (1997) 'Association between interleukin-1 receptor antagonist (IL-1ra) gene polymorphism and early and late-onset psoriasis [16]'. British Journal of Dermatology, 136 (1). pp. 147 - 148. ISSN: 0007-0963
Blakemore, AIF., Cox, A., Gonzalez, AM., Maskill, JK., Hughes, ME., Wilson, RM., et al. (1996) 'Interleukin-1 receptor antagonist allele (IL1RN*2) associated with nephropathy in diabetes mellitus'. Human Genetics, 97 (3). pp. 369 - 374. ISSN: 0340-6717
Cork, MJ., Tarlow, JK., Clay, FE., Crane, A., Blakemore, AIF., McDonagh, AJG., et al. (1995) 'An Allele of the Interleukin-1 Receptor Antagonist as a Genetic Severity Factor in Alopecia Areata'. Journal of Investigative Dermatology, 104 (5). pp. 15 - 16. ISSN: 0022-202X
Blakemore, AIF., Watson, PF., Weetman, AP. and Duff, GW. (1995) 'Association of Graves' disease with an allele of the interleukin-1 receptor antagonist gene'. Journal of Clinical Endocrinology and Metabolism, 80 (1). pp. 111 - 115. ISSN: 0021-972X
Tarlow, JK., Clay, FE., Cork, MJ., Blakemore, AIF., McDonagh, AJG., Messenger, AG. and et al. (1994) 'Severity of alopecia areata is associated with a polymorphism in the interleukin-1 receptor antagonist gene'. Journal of Investigative Dermatology, 103 (3). pp. 387 - 390. ISSN: 0022-202X
Blakemore, AIF., Tarlow, JK., J.Cork, M., Gordon, C., Emery, P. and Duff, GW. (1994) 'Interleukin–1 receptor antagonist gene polymorphism as a disease severity factor in systemic lupus erythematosus'. Arthritis & Rheumatism, 37 (9). pp. 1380 - 1385. ISSN: 0004-3591
Tarlow, JK., Blakemore, AIF., Lennard, A., Solari, R., Hughes, HN., Steinkasserer, A. and et al. (1993) 'Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat'. Human Genetics, 91 (4). pp. 403 - 404. ISSN: 0340-6717
MANSFIELD, JC., TARLOW, JK., HOLDEN, H., BLAKEMORE, AIF., HOLDSWORTH, CD. and DUFF, GW. (1993) 'ULCERATIVE-COLITIS IS ASSOCIATED WITH THE RARER ALLELE OF INTERLEUKIN-1 RECEPTOR ANTAGONIST GENE'. GASTROENTEROLOGY, 104 (4). pp. A736 - A736. ISSN: 0016-5085
Bailly, S., Di Giovine, FS., Blakemore, AIF. and Duff, GW. (1993) 'Genetic polymorphism of human interleukin‐1α'. European Journal of Immunology, 23 (6). pp. 1240 - 1245. ISSN: 0014-2980
Giovine, FSD., Takhsh, E., Blakemore, AIF. and Duff, GW. (1992) 'Single base polymorphism at -511 in the human interleukin-1β gene (IL1β)'. Human Molecular Genetics, 1 (6). pp. 450. ISSN: 0964-6906
Wilson, AG., Di Giovine, FS., Blakemore, AIF. and Duff, GW. (1992) 'Single base polymorphism in the human tumour necrosis factor alpha (TNFα) gene detectable by Ncol restriction of PCR product'. Human Molecular Genetics, 1 (5). pp. 353. ISSN: 0964-6906
Curtis, D., Blakemore, AI., Engel, PC., Kolvraa, S., Gregersen, N. and Pollitt, RJ. (1992) 'Medium chain acyl-CoA dehydrogenase deficiency in the United Kingdom.'. Progress in clinical and biological research, 375. pp. 489 - 494. ISSN: 0361-7742
GREGERSEN, N., WINTER, V., KOLVRAA, S., ANDRESEN, BS., BROSS, P., BLAKEMORE, A., et al. (1992) 'MOLECULAR ANALYSIS OF MEDIUM-CHAIN ACYL-COA DEHYDROGENASE-DEFICIENCY - A DIAGNOSTIC-APPROACH'.2ND INTERNATIONAL SYMP ON CLINICAL, BIOCHEMICAL, AND MOLECULAR ASPECTS OF FATTY ACID OXIDATION. PHILADELPHIA, PA. 1 WILEY-LISS, INC. pp. 441 - 452. ISSN: 0361-7742
Gregersen, N., Blakemore, AIF., Winter, V., Andresen, B., Kølvraa, S., Bolund, L., et al. (1991) 'Specific diagnosis of medium-chain acyl-CoA dehydrogenase (MCAD) deficiency in dried blood spots by a polymerase chain reaction (PCR) assay detecting a point-mutation (G985) in the MCAD gene'. Clinica Chimica Acta, 203 (1). pp. 23 - 34. ISSN: 0009-8981
Kølvraa, S., Gregersen, N., Blakemore, AIF., Schneidermann, AK., Winter, V., Andresen, BS., et al. (1991) 'The most common mutation causing medium-chain acyl-CoA dehydrogenase deficiency is strongly associated with a particular haplotype in the region of the gene'. Human Genetics, 87 (4). pp. 425 - 428. ISSN: 0340-6717
Gregersen, N., Andresen, BS., Bross, P., Winter, V., Rüdiger, N., Engst, S., et al. (1991) 'Characterization of a disease-causing Lys329 to Glu mutation in 16 patients with medium-chain Acyl-CoA dehydrogenase deficiency'.SYMP AT THE 28TH ANNUAL MEETING OF THE SOC FOR THE STUDY OF INBORN ERRORS OF METABOLISM : LIVER AND INHERITED METABOLIC DISORDERS. BIRMINGHAM, ENGLAND. 1 - 7 September. Wiley. pp. 314 - 316. ISSN: 0141-8955
Blakemore, AF., Singleton, H., Pollitt, R., Engel, P., Kolvraa, S., Gregersen, N. and et al. (1991) 'Frequency of the G985 MCAD mutation in the general population'. The Lancet, 337 (8736). pp. 298 - 299. ISSN: 0140-6736
Curtis, D., Blakemore, AIF., Engel, PC., Macgregor, D., Besley, G., Kolvraa, S. and et al. (1991) 'Heterogeneity for mutations in medium chain acyl‐CoA dehydrogenase deficiency in the UK population'. Clinical Genetics, 40 (4). pp. 283 - 286. ISSN: 0009-9163
Blakemore, AIF., Kolvraa, S., Gregersen, N., Engel, PC. and Curtis, D. (1991) 'Localisation of RFLPs of the medium chain acyl-CoA dehydrogenase gene'. Human Genetics, 86 (5). pp. 537 - 538. ISSN: 0340-6717
Blakemore, A., Curtis, D. and Engel, P. (1991) 'Understanding MCAD deficiency: one cause of cot death'. Current Biology, 1 (3). pp. 195 - 197. ISSN: 0960-9822
Blakemore, AIF., Engel, PC. and Curtis, D. (1990) 'BamHI and Mspl RFLP's in strong linkage disequilibrium at the medium chain acyl-coenzyme A dehydrogenase locus (ACADM chromsome 1)'. Nucleic Acids Research, 18 (9). pp. 2838. ISSN: 0305-1048