Professor Andreas Kortenkamp
Professor - Human Molecular Toxicology
Heinz Wolff 001E
- Email: andreas.kortenkamp@brunel.ac.uk
- Tel: +44 (0)1895 266525
- Environmental Sciences
- Department of Life Sciences
- College of Health, Medicine and Life Sciences
Brack, W., Altenburger, R., Schüürmann, G., Krauss, M., López Herráez, D., van Gils, J., et al. (2015) 'The SOLUTIONS project: Challenges and responses for present and future emerging pollutants in land and water resources management'. Science of the Total Environment, 503-504. pp. 22 - 31. ISSN: 0048-9697 Open Access Link
Trasande, L., Zoeller, RT., Hass, U., Kortenkamp, A., Grandjean, P., Myers, JP., et al. (2015) 'Estimating burden and disease costs of exposure to endocrine-disrupting chemicals in the European Union'. Journal of Clinical Endocrinology and Metabolism, 100 (4). pp. 1245 - 1255. ISSN: 0021-972X
Bergman, Å., Becher, G., Blumberg, B., Bjerregaard, P., Bornman, R., Brandt, I., et al. (2015) 'Manufacturing doubt about endocrine disrupter science - A rebuttal of industry-sponsored critical comments on the UNEP/WHO report "State of the Science of Endocrine Disrupting Chemicals 2012"'. Regulatory Toxicology and Pharmacology, 73 (3). pp. 1007 - 1017. ISSN: 0273-2300 Open Access Link
Zoeller, RT., Bergman, A., Becher, G., Bjerregaard, P., Bornman, R., Brandt, I., et al. (2014) 'A path forward in the debate over health impacts of endocrine disrupting chemicals'. Environmental Health, 13 (1). pp. 118. ISSN: 1832-3367 Open Access Link
Kortenkamp, A. (2014) 'Low dose mixture effects of endocrine disrupters and their implications for regulatory thresholds in chemical risk assessment'. Current Opinion in Pharmacology, 19. pp. 105 - 111. ISSN: 1471-4892
Lioy, PJ., Gennings, C., Hauser, R., Koch, HM. and Kortenkamp, A. (2014) 'Changing trends in phthalate exposures'. Environmental Health Perspectives, 122 (10). pp. 264 - 264. ISSN: 0091-6765 Open Access Link
Orton, F., Ermler, S., Kugathas, S., Rosivatz, E., Scholze, M. and Kortenkamp, A. (2014) 'Mixture effects at very low doses with combinations of anti-androgenic pesticides, antioxidants, industrial pollutant and chemicals used in personal care products'. Toxicology and Applied Pharmacology, 278 (3). pp. 201 - 208. ISSN: 0041-008X Open Access Link
Martin, O., Kortenkamp, A., Evans, R., Faust, M. and Backhaus, T. (2014) 'Risk of Combination Effects Between Decabromodiphenyl Ether and Other Polybrominated Diphenyl Ethers'. Place of publication: Miljødirektoratet. Available at: http://www.miljodirektoratet.no/Documents/publikasjoner/M223/M223.pdf.
Riverso, M., Kortenkamp, A. and Silva, E. (2014) 'Non-tumorigenic epithelial cells secrete MCP-1 and other cytokines that promote cell division in breast cancer cells by activating ERα via PI3K/Akt/mTOR signaling'. International Journal of Biochemistry and Cell Biology, 53. pp. 281 - 294. ISSN: 1357-2725 Open Access Link
Kortenkamp, A., Scholze, M. and Ermler, S. (2014) 'Mind the gap: Can we explain declining male reproductive health with known antiandrogens?'. Reproduction, 147 (4). pp. 515 - 527. ISSN: 1470-1626 Open Access Link
Ermler, S., Scholze, M. and Kortenkamp, A. (2014) 'Genotoxic mixtures and dissimilar action: Concepts for prediction and assessment'. Archives of Toxicology, 88 (3). pp. 799 - 814. ISSN: 0340-5761 Open Access Link
Scholze, M., Silva, E. and Kortenkamp, A. (2014) 'Extending the applicability of the dose addition model to the assessment of chemical mixtures of partial agonists by using a novel toxic unit extrapolation method'. PLoS ONE, 9 (2). pp. e88808 - e88808. ISSN: 1932-6203 Open Access Link
Isling, LK., Boberg, J., Jacobsen, PR., Mandrup, KR., Axelstad, M., Christiansen, S., et al. (2014) 'Late-life effects on rat reproductive system after developmental exposure to mixtures of endocrine disrupters'. Reproduction, 147 (4). pp. 465 - 476. ISSN: 1470-1626
Axelstad, M., Christiansen, S., Boberg, J., Scholze, M., Jacobsen, PR., Isling, LK., et al. (2014) 'Mixtures of endocrine-disrupting contaminants induce adverse developmental effects in preweaning rats'. Reproduction, 147 (4). pp. 489 - 501. ISSN: 1470-1626
Pottinger, TG., Katsiadaki, I., Jolly, C., Sanders, M., Mayer, I., Scott, AP., et al. (2013) 'Anti-androgens act jointly in suppressing spiggin concentrations in androgen-primed female three-spined sticklebacks - Prediction of combined effects by concentration addition'. Aquatic Toxicology, 140-141. pp. 145 - 156. ISSN: 0166-445X Open Access Link
Kortenkamp, A. (2013) 'How is new science used in regulatory approaches for dealing with endocrine disrupters?'.49th Congress of the European-Societies-of-Toxicology (EUROTOX). Interlaken, SWITZERLAND. 1 - 4 September. ELSEVIER IRELAND LTD. pp. S37 - S37. ISSN: 0378-4274
Lichtensteiger, W., Bassetti-Gaille, C., Faass, O., Boberg, J., Christiansen, S., Hass, U., et al. (2013) 'Effects of different endocrine disruptor (EDC) mixtures on gene expression in neonatal rat brain regions: Focus on developing excitatory synapses'.49th Congress of the European-Societies-of-Toxicology (EUROTOX). Interlaken, SWITZERLAND. 1 - 4 September. ELSEVIER IRELAND LTD. pp. S106 - S106. ISSN: 0378-4274
Bergman, A., Andersson, A-M., Becher, G., van den Berg, M., Blumberg, B., Bjerregaard, P., et al. (2013) 'Science and policy on endocrine disrupters must not be mixed: A reply to a "common sense" intervention by toxicology journal editors'. Environmental Health, 12 (1). pp. 69. ISSN: 1476-069X Open Access Link
Martin, OV., Martin, S. and Andreas, K. (2013) 'Dispelling urban myths about default uncertainty factors in chemical risk assessment - Sufficient protection against mixture effects?'. Environmental Health: A Global Access Science Source, 12 (1). pp. 53. ISSN: 1476-069X Open Access Link
Ermler, S., Scholze, M. and Kortenkamp, A. (2013) 'Seven benzimidazole pesticides combined at sub-threshold levels induce micronuclei in vitro'. Mutagenesis, 28 (4). pp. 417 - 426. ISSN: 0267-8357 Open Access Link
Rahte, S., Evans, R., Eugster, PJ., Marcourt, L., Wolfender, JL., Kortenkamp, A. and et al. (2013) 'Salvia officinalis for hot flushes: Towards determination of mechanism of activity and active principles'. Planta Medica, 79 (9). pp. 753 - 760. ISSN: 0032-0943
Bergman, Å., Heindel, JJ., Kasten, T., Byléhn, AS., Kidd, KA., Jobling, S., et al. (2013) 'The impact of endocrine disruption: A consensus statement on the state of the science'. Environmental Health Perspectives, 121 (4). pp. a104 - a106. ISSN: 0091-6765 Open Access Link
Krug, AK., Kolde, R., Gaspar, JA., Rempel, E., Balmer, NV., Meganathan, K., et al. (2013) 'Human embryonic stem cell-derived test systems for developmental neurotoxicity: A transcriptomics approach'. Archives of Toxicology, 87 (1). pp. 123 - 143. ISSN: 0340-5761 Open Access Link
Rahte, S., Tasdemir, D., Evans, R., Kortenkamp, A., Eugster, PJ., Marcourt, L. and et al. (2013) 'Salvia officinalis for Hot Flushes: Towards Determination of Mechanism of Activity and Active Principles'. Planta Medica, 79 (13). pp. 1274 - 1274. ISSN: 0032-0943
Orton, F., Rosivatz, E., Scholze, M. and Kortenkamp, A. (2012) 'Competitive androgen receptor antagonism as a factor determining the predictability of cumulative antiandrogenic effects of widely used pesticides'. Environmental Health Perspectives, 120 (11). pp. 1578 - 1584. ISSN: 0091-6765 Open Access Link
Kortenkamp, A., Martin, O., Evans, R., Orton, F., McKinlay, R., Rosivatz, E. and et al. (2012) 'Response to A critique of the European commission document, "state of the art assessment of endocrine disrupters" by Rhomberg and colleagues letter to the editor'. Critical Reviews in Toxicology, 42 (9). pp. 787 - 789. ISSN: 1040-8444
Evans, RM., Scholze, M. and Kortenkamp, A. (2012) 'Additive mixture effects of estrogenic chemicals in human cell-based assays can be influenced by inclusion of chemicals with differing effect profiles'. PLoS One, 7 (8). pp. e43606 - e43606. ISSN: 1932-6203 Open Access Link
Christiansen, S., Kortenkamp, A., Axelstad, M., Boberg, J., Scholze, M., Jacobsen, PR., et al. (2012) 'Mixtures of endocrine disrupting contaminants modelled on human high end exposures: An exploratory study in rats'. International Journal of Andrology, 35 (3). pp. 303 - 316. ISSN: 0105-6263
Snijder, CA., Kortenkamp, A., Steegers, EAP., Jaddoe, VWV., Hofman, A., Hass, U. and et al. (2012) 'Intrauterine exposure to mild analgesics during pregnancy and the occurrence of cryptorchidism and hypospadia in the offspring: The Generation R Study'. Human Reproduction, 27 (4). pp. 1191 - 1201. ISSN: 1460-2350 Open Access Link
Christiansen, S., Kortenkamp, A., Axelstad, M., Boberg, J., Scholze, M., Jacobsen, PR., et al. (2012) 'Mixtures of endocrine disrupting contaminants modelled on human high end exposures: An exploratory study in rats'. International Journal of Andrology. ISSN: 0105-6263
Ermler, S., Scholze, M. and Kortenkamp, A. (2011) 'The suitability of concentration addition for predicting the effects of multi-component mixtures of up to 17 anti-androgens with varied structural features in an in vitro AR antagonist assay'. Toxicology and Applied Pharmacology, 257 (2). pp. 189 - 197. ISSN: 0041-008X
Silva, E., Rajapakse, N., Scholze, M., Backhaus, T., Ermler, S. and Kortenkamp, A. (2011) 'Joint effects of heterogeneous estrogenic chemicals in the E-Screen-exploring the applicability of concentration addition'. Toxicological Sciences, 122 (2). pp. 383 - 394. ISSN: 1096-6080
Orton, F., Rosivatz, E., Scholze, M. and Kortenkamp, A. (2011) 'Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens'. Environ Health Perspect, 119 (6). pp. 794 - 800. ISSN: 0091-6765 Open Access Link
Kortenkamp, A. (2011) 'Are cadmium and other heavy metal compounds acting as endocrine disrupters?'. Metal ions in life sciences, 8. pp. 305 - 317. ISSN: 1559-0836
Modarai, M., Suter, A., Kortenkamp, A. and Heinrich, M. (2011) 'The interaction potential of herbal medicinal products: A luminescence-based screening platform assessing effects on cytochrome P450 and its use with devil's claw (Harpagophyti radix) preparations'. Journal of Pharmacy and Pharmacology, 63 (3). pp. 429 - 438. ISSN: 0022-3573
Modarai, M., Silva, E., Suter, A., Heinrich, M. and Kortenkamp, A. (2011) 'Safety of Herbal Medicinal Products: Echinacea and Selected Alkylamides Do Not Induce CYP3A4 mRNA Expression'. Evidence Based Complementary Alternative Medicine, 2011 (1). pp. 213021 - 213021. ISSN: 1741-427X Open Access Link
Ermler, S., Scholze, M. and Kortenkamp, A. (2010) 'The sensitivity of the MDA-kb2 cell in vitro assay in detecting anti-androgenic chemicals - Identification of sources of variability and estimation of statistical power'. Toxicology in Vitro, 24 (6). pp. 1845 - 1853. ISSN: 0887-2333
Evans, RM., Rahte, S. and Kortenkamp, A. (2010) 'Inability to confirm estrogenicity of the heterocyclic amine PhIP in two in vitro assays'. Toxicology in Vitro, 24 (6). pp. 1757 - 1763. ISSN: 0887-2333
Rahte, S., Suter, A., Kortenkamp, A. and Tasdemir, D. (2010) 'Selective serotonin re-uptake and acetylcholinesterase inhibitory activities of Salvia officinalis'.7th Tannin Conference/58th International Congress and Annual Meeting of the Society-for-Medical-Plant-and-Natural-Product-Research. Berlin, GERMANY. 29 - 2 September. GEORG THIEME VERLAG KG. pp. 1213 - 1213. ISSN: 0032-0943
Silva, E., Kabil, A. and Kortenkamp, A. (2010) 'Cross-talk between non-genomic and genomic signalling pathways - Distinct effect profiles of environmental estrogens'. Toxicology and Applied Pharmacology, 245 (2). pp. 160 - 170. ISSN: 0041-008X
Modarai, M., Yang, M., Suter, A., Kortenkamp, A. and Heinrich, M. (2010) 'Metabolomic profiling of liquid echinacea medicinal products with in vitro inhibitory effects on cytochrome P450 3A4 (CYP3A4)'. Planta Medica, 76 (4). pp. 378 - 385. ISSN: 0032-0943
Kortenkamp, A. and Faust, M. (2010) 'Combined exposures to anti-androgenic chemicals: Steps towards cumulative risk assessment'. International Journal of Andrology, 33 (2). pp. 463 - 474. ISSN: 0105-6263
Christiansen, S., Dalgaard, M., Vinggaard, AM., Axelstad, M., Hass, U., Scholze, M. and et al. (2009) 'Synergistic disruption of external male sex organ development by a mixture of four antiandrogens'. Environmental Health Perspectives, 117 (12). pp. 1839 - 1846. ISSN: 0091-6765 Open Access Link
Modarai, M., Silva, E., Suter, A., Heinrich, M. and Kortenkamp, A. (2009) 'The effects of Echinacea and its alkylamides on CYP3A4 transcriptional activity'.55th International Congress and Annual Meeting of the Society-for-Medicinal-Plant-Research-and-Natural-Product-Research. Geneva, SWITZERLAND. 16 - 20 August. GEORG THIEME VERLAG KG. pp. 998 - 998. ISSN: 0032-0943
Lopez-Espinosa, M-J., Silva, E., Granada, A., Molina-Molina, J-M., Fernandez, MF., Aguilar-Garduno, C., et al. (2009) 'Assessment of the total effective xenoestrogen burden in extracts of human placentas'. Biomarkers, 14 (5). pp. 271 - 277. ISSN: 1366-5804
Modarai, M., Suter, A., Kortenkamp, A. and Heinrich, M. (2008) 'CYP3A4 inhibitory compounds from Echinacea extract (Echinaforce (R))'. PLANTA MEDICA, 74 (9). pp. 1070 - 1071. ISSN: 0032-0943
Brian, JV., Harris, CA., Runnalls, TJ., Fantinati, A., Pojana, G., Marcomini, A., et al. (2008) 'Evidence of temperature-dependent effects on the estrogenic response of fish: Implications with regard to climate change'. Science of The Total Environment, 397 (1-3). pp. 72 - 81. ISSN: 0048-9697 Open Access Link
Kortenkamp, A. (2008) 'Breast cancer and environmental risk factors: an appraisal of the scientific evidence'.Breast Cancer Research Meeting. London, ENGLAND. 13 BIOMED CENTRAL LTD. pp. S24 - S24. ISSN: 1465-5411
Heinrich, M., Modarai, M. and Kortenkamp, A. (2008) 'Herbal extracts used for upper respiratory tract infections: Are there clinically relevant interactions with the cytochrome P450 enzyme system?'. Planta Medica, 74 (6). pp. 657 - 660. ISSN: 0032-0943
Kortenkamp, A. (2008) 'Combined effects of endocrine disruptors: Evaluation of the last 10 years'. Environnement, Risques et Sante, 7 (3). pp. 172. ISSN: 1635-0421
Kabil, A., Silva, E. and Kortenkamp, A. (2008) 'Estrogens and genomic instability in human breast cancer cells - Involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals'. Carcinogenesis, 29 (10). pp. 1862 - 1868. ISSN: 0143-3334 Open Access Link