Dr Christian Rudolph
Reader
Heinz Wolff 112
- Email: christian.rudolph@brunel.ac.uk
- Tel: +44 (0)1895 265372
Killelea, T., Dimude, JU., He, L., Stewart, AL., Kemm, FE., Radovčić, M., et al. (2023) 'Cas1-Cas2 physically and functionally interacts with DnaK to modulate CRISPR Adaptation'. Nucleic Acids Research, 51 (13). pp. 6914 - 6926. ISSN: 0305-1048 Open Access Link
Goodall, DJ., Warecka, D., Hawkins, M. and Rudolph, CJ. (2023) 'Interplay between chromosomal architecture and termination of DNA replication in bacteria'. Frontiers in Microbiology, 14. pp. 1 - 19. ISSN: 1664-302X Open Access Link
de Dios, R., Proctor, CR., Maslova, E., Dzalbe, S., Rudolph, CJ. and McCarthy, RR. (2022) 'Artificial sweeteners inhibit multidrug‐resistant pathogen growth and potentiate antibiotic activity'. EMBO Molecular Medicine, 15 (1). pp. 1 - 21. ISSN: 1757-4676 Open Access Link
Jameson, KH., Rudolph, C. and Hawkins, M. (2021) 'Termination of DNA replication at Tus-ter barriers results in under-replication of template DNA'. Journal of Biological Chemistry, 297 (6). pp. 1 - 14. ISSN: 0021-9258 Open Access Link
Goodall, DJ., Jameson, KH., Hawkins, M. and Rudolph, CJ. (2021) 'A fork trap in the chromosomal termination area is highly conserved across all Escherichia coli phylogenetic groups'. International Journal of Molecular Sciences, 22 (15). pp. 1 - 24. ISSN: 1661-6596 Open Access Link
Syeda, A., Dimude, J., Skovgaard, O. and Rudolph, C. (2020) 'Too much of a good thing: how ectopic DNA replication affects bacterial replication dynamics'. Frontiers in Microbiology, 11. pp. 1 - 21. ISSN: 1664-302X Open Access Link
Hawkins, M., Dimude, JU., Howard, JAL., Smith, AJ., Dillingham, MS., Savery, NJ., et al. (2019) 'Direct removal of RNA polymerase barriers to replication by accessory replicative helicases'. Nucleic Acids Research, 47 (10). pp. 5100 - 5113. ISSN: 0305-1048 Open Access Link
Rudolph, C., Corocher, T-A., Grainge, I. and Duggin, IG. (2019) 'Termination of DNA Replication in Prokaryotes', inEncyclopedia of Life Sciences. Wiley [Imprint] Hoboken. pp. 1 - 15. ISBN 10: 047001590X. ISBN 13: 9780470016176. Open Access Link
Midgley-Smith, S., Dimude, J. and Rudolph, C. (2018) 'A role for 3’ exonucleases at the final stages of chromosome duplication in Escherichia coli'. Nucleic Acids Research, 47 (4). pp. 1847 - 1860. ISSN: 0305-1048 Open Access Link
Dimude, JU., Midgley-Smith, SL. and Rudolph, CJ. (2018) 'Replication-transcription conflicts trigger extensive DNA degradation in Escherichia coli cells lacking RecBCD'. Mutation Research/DNA Repair, 70. pp. 37 - 48. ISSN: 0921-8777 Open Access Link
Dimude, JU., Stein, M., Andrzejewska, EE., Khalifa, MS., Gajdosova, A., Retkute, R., et al. (2018) 'Origins Left, Right, and Centre: Increasing the Number of Initiation Sites in the Escherichia coli Chromosome'. Genes, 9 (8). pp. 1 - 21. ISSN: 2073-4425 Open Access Link
Midgley-Smith, SL., Dimude, JU., Taylor, T., Forrester, NM., Upton, AL., Lloyd, RG. and et al. (2018) 'Chromosomal over-replication in Escherichia coli recG cells is triggered by replication fork fusion and amplified if replichore symmetry is disturbed'. Nucleic Acids Research, 46 (15). pp. 7701 - 7715. ISSN: 0305-1048 Open Access Link
Dimude, JU., Midgley-Smith, SL., Stein, M. and Rudolph, C. (2016) 'Replication Termination: Containing Fork Fusion-Mediated Pathologies in Escherichia coli'. Genes, 7 (8). pp. 40 - 40. ISSN: 2073-4425 Open Access Link
Lloyd, RG. and Rudolph, CJ. (2016) '25 years on and no end in sight: a perspective on the role of RecG protein.'. Current Genetics, 62 (4). pp. 827 - 840. ISSN: 0172-8083 Open Access Link
Dimude, JU., Stockum, A., Midgley-Smith, SL., Upton, AL., Foster, HA., Khan, A., et al. (2015) 'The consequences of replicating in the wrong orientation: bacterial chromosome duplication without an active replication origin'. mBio, 6 (6). pp. e01294 - e01215. ISSN: 2150-7511 Open Access Link
Ivanova, D., Taylor, T., Smith, SL., Dimude, JU., Upton, AL., Mehrjouy, M., et al. (2015) 'Shaping the landscape of the Escherichia coli chromosome: replication-transcription encounters in cells with an ectopic replication origin'. Nucleic Acids Research, 43 (16). pp. 7865 - 7877. ISSN: 1362-4962 Open Access Link
Upton, AL., Grove, JI., Mahdi, AA., Briggs, GS., Milner, DS., Rudolph, CJ. and et al. (2014) 'Cellular location and activity of Escherichia coli RecG proteins shed light on the function of its structurally unresolved C-terminus'. Nucleic Acids Research, 42 (9). pp. 5702 - 5714. ISSN: 0305-1048 Open Access Link
Rudolph, CJ., Upton, AL., Stockum, A., Nieduszynski, CA. and Lloyd, RG. (2013) 'Avoiding chromosome pathology when replication forks collide'. Nature, 500 (7464). pp. 608 - 611. ISSN: 0028-0836 Open Access Link
Stockum, A., Lloyd, RG. and Rudolph, C. (2012) 'On the viability of Escherichia coli cells lacking DNA topoisomerase I'. BMC Microbiology, 12 (1). pp. 26. ISSN: 1471-2180 Open Access Link
Atkinson, J., Gupta, MK., Bell, H., McGlynn, P., Rudolph, CJ. and Lloyd, RG. (2011) 'Localization of an accessory helicase at the replisome is critical in sustaining efficient genome duplication'. Nucleic Acids Research, 39 (3). pp. 949 - 957. ISSN: 0305-1048 Open Access Link
Ede, C., Rudolph, CJ., Lehmann, S., Schürer, KA. and Kramer, W. (2011) 'Budding yeast Mph1 promotes sister chromatid interactions by a mechanism involving strand invasion'. DNA Repair, 10 (1). pp. 45 - 55. ISSN: 1568-7864
Rudolph, CJ., Mahdi, AA., Upton, AL. and Lloyd, RG. (2010) 'RecG protein and single-strand DNA exonucleases avoid cell lethality associated with PriA helicase activity in Escherichia coli'. Genetics, 186 (2). pp. 473 - 492. ISSN: 0016-6731
Rudolph, CJ., Upton, AL., Briggs, GS. and Lloyd, RG. (2010) 'Is RecG a general guardian of the bacterial genome?'. DNA Repair, 9 (3). pp. 210 - 223. ISSN: 1568-7864
Guy, CP., Atkinson, J., Gupta, MK., Mahdi, AA., Gwynn, EJ., Rudolph, CJ., et al. (2009) 'Rep Provides a Second Motor at the Replisome to Promote Duplication of Protein-Bound DNA'. Molecular Cell, 36 (4). pp. 654 - 666. ISSN: 1097-2765
Rudolph, CJ., Upton, AL. and Lloyd, RG. (2009) 'Replication fork collisions cause pathological chromosomal amplification in cells lacking RecG DNA translocase'. Molecular Microbiology, 74 (4). pp. 940 - 955. ISSN: 0950-382X Open Access Link
Rudolph, CJ., Upton, AL., Harris, L. and Lloyd, RG. (2009) 'Pathological replication in cells lacking RecG DNA translocase'. Molecular Microbiology, 73 (3). pp. 352 - 366. ISSN: 0950-382X Open Access Link
Rudolph, CJ., Upton, AL. and Lloyd, RG. (2008) 'Maintaining replication fork integrity in UV-irradiated Escherichia coli cells'. DNA Repair, 7 (9). pp. 1589 - 1602. ISSN: 1568-7864
Rudolph, CJ., Dhillon, P., Moore, T. and Lloyd, RG. (2007) 'Avoiding and resolving conflicts between DNA replication and transcription'. DNA Repair, 6 (7). pp. 981 - 993. ISSN: 1568-7864
Rudolph, CJ., Upton, AL. and Lloyd, RG. (2007) 'Replication fork stalling and cell cycle arrest in UV-irradiated Escherichia coli'. Genes and Development, 21 (6). pp. 668 - 681. ISSN: 0890-9369
Rudolph, C., Schürer, KA. and Kramer, W. (2007) 'Facing Stalled Replication Forks: The Intricacies of Doing the Right Thing', in Lankenau, D-H. (ed.) Genome Integrity: Facets and Perspectives. Springer. , 1. pp. 105 - 152. ISBN 13: 978-3-540-37531-9.
Schürer, KA., Rudolph, C., Ulrich, HD. and Kramer, W. (2004) 'Yeast MPH1 Gene Functions in an Error-Free DNA Damage Bypass Pathway That Requires Genes from Homologous Recombination, but Not from Postreplicative Repair'. Genetics, 166 (4). pp. 1673 - 1686. ISSN: 0016-6731
Scheller, J., Schürer, A., Rudolph, C., Hettwer, S. and Kramer, W. (2000) 'MPH1, a yeast gene encoding a DEAH protein, plays a role in protection of the genome from spontaneous and chemically induced damage'. Genetics, 155 (3). pp. 1069 - 1081. ISSN: 0016-6731