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Dr Cristiano Scotta
Lecturer in Biosciences

Headen, K., Jakaite, V., Mesaric, VA., Scottá, C., Lombardi, G., Nicolaides, KH. and et al. (2024) 'The Role of Regulatory T Cells and Their Therapeutic Potential in Hypertensive Disease of Pregnancy: A Literature Review'. International Journal of Molecular Sciences, 25 (9). pp. 1 - 14. ISSN: 1661-6596 Open Access Link

Journal article

Dudreuilh, C., Jarvis, P., Beadle, N., Pilecka, I., Shaw, O., Gardner, L., et al. (2023) 'Can regulatory T cells improve outcomes of sensitised patients after HLA-Ab incompatible renal transplantation: study protocol for the Phase IIa GAMECHANgER-1 trial'. BMC Nephrology, 24 (1). pp. 1 - xx. ISSN: 1471-2369 Open Access Link

Journal article

Stroukov, W., Mastronicola, D., Albany, CJ., Catak, Z., Lombardi, G. and Scottà, C. (2023) 'OMIP-090: A 20-parameter flow cytometry panel for rapid analysis of cell diversity and homing capacity in human conventional and regulatory T cells'. Cytometry Part A, 103 (5). pp. 362 - 367. ISSN: 1552-4922 Open Access Link

Journal article

Dudreuilh, C., Basu, S., Shaw, O., Burton, H., Mamode, N., Harris, F., et al. (2023) 'Highly sensitised individuals present a distinct Treg signature compared to unsensitised individuals on haemodialysis'. Frontiers in Transplantation, 2. pp. 1165320. ISSN: 2813-2440

Journal article

Efthymiou, A., Mureanu, N., Pemberton, R., Tai-MacArthur, S., Mastronicola, D., Scottà, C., et al. (2022) 'Isolation and freezing of human peripheral blood mononuclear cells from pregnant patients'. STAR Protocols, 3 (1). pp. 1 - 8. ISSN: 2666-1667 Open Access Link

Journal article

Green, S., Politis, M., Rallis, KS., Saenz de Villaverde Cortabarria, A., Efthymiou, A., Mureanu, N., et al. (2021) 'Regulatory T Cells in Pregnancy Adverse Outcomes: A Systematic Review and Meta-Analysis'. Frontiers in Immunology, 12. pp. 1 - 13. ISSN: 1664-3224 Open Access Link

Journal article

Mohseni, YR., Saleem, A., Tung, SL., Dudreuilh, C., Lang, C., Peng, Q., et al. (2021) 'Chimeric antigen receptor-modified human regulatory T cells that constitutively express IL-10 maintain their phenotype and are potently suppressive'. European Journal of Immunology, 51 (10). pp. 2522 - 2530. ISSN: 0014-2980 Open Access Link

Journal article

Romano, M., Sen, M., Scottà, C., Alhabbab, RY., Rico-Armada, A., Lechler, RI., et al. (2021) 'Isolation and expansion of thymus-derived regulatory T cells for use in pediatric heart transplant patients'. European Journal of Immunology, 51 (8). pp. 2086 - 2092. ISSN: 0014-2980 Open Access Link

Journal article

Dudreuilh, C., Basu, S., Scottà, C., Dorling, A. and Lombardi, G. (2021) 'Potential Application of T-Follicular Regulatory Cell Therapy in Transplantation'. Frontiers in Immunology, 11. pp. 1 - 18. ISSN: 1664-3224 Open Access Link

Journal article

Giganti, G., Atif, M., Mohseni, Y., Mastronicola, D., Grageda, N., Povoleri, GAM., et al. (2021) 'Treg cell therapy: How cell heterogeneity can make the difference'. European Journal of Immunology, 51 (1). pp. 39 - 55. ISSN: 0014-2980

Journal article

Jacob, J., Nadkarni, S., Volpe, A., Peng, Q., Tung, SL., Hannen, RF., et al. (2020) 'Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment'. Molecular Therapy Methods and Clinical Development, 20. pp. 324 - 336. ISSN: 2329-0501 Open Access Link

Journal article

Harden, PN., Game, DS., Sawitzki, B., Van der Net, JB., Hester, J., Bushell, A., et al. (2020) 'Feasibility, long-term safety, and immune monitoring of regulatory T cell therapy in living donor kidney transplant recipients'. American Journal of Transplantation, 21 (4). pp. 1603 - 1611. ISSN: 1600-6135 Open Access Link

Journal article

Sawitzki, B., Harden, PN., Reinke, P., Moreau, A., Hutchinson, JA., Game, DS., et al. (2020) 'Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials'. The Lancet, 395 (10237). pp. 1627 - 1639. ISSN: 0140-6736 Open Access Link

Journal article

Albany, CJ., Trevelin, SC., Giganti, G., Lombardi, G. and Scottà, C. (2019) 'Getting to the Heart of the Matter: The Role of Regulatory T-Cells (Tregs) in Cardiovascular Disease (CVD) and Atherosclerosis'. Frontiers in Immunology, 10. pp. 1 - 11. ISSN: 1664-3224 Open Access Link

Journal article

Cossarizza, A., Chang, H-D., Radbruch, A., Acs, A., Adam, D., Adam-Klages, S., et al. (2019) 'Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)'. European Journal of Immunology, 49 (10). pp. 1457 - 1973. ISSN: 0014-2980 Open Access Link

Journal article

Goldberg, R., Scotta, C., Cooper, D., Nissim-Eliraz, E., Nir, E., Tasker, S., et al. (2019) 'Correction of Defective T-Regulatory Cells From Patients With Crohn's Disease by Ex Vivo Ligation of Retinoic Acid Receptor-α'. Gastroenterology, 156 (6). pp. 1775 - 1787. ISSN: 0016-5085

Journal article

Povoleri, GAM., Nova-Lamperti, E., Scottà, C., Fanelli, G., Chen, YC., Becker, PD., et al. (2018) 'Human retinoic acid–regulated CD161 + regulatory T cells support wound repair in intestinal mucosa'. Nature Immunology, 19 (12). pp. 1403 - 1414. ISSN: 1529-2908

Journal article

Romano, M., Fanelli, G., Tan, N., Nova-Lamperti, E., McGregor, R., Lechler, RI., et al. (2018) 'Expanded regulatory T cells induce alternatively activated monocytes with a reduced capacity to expand T helper-17 cells'. Frontiers in Immunology, 9 (JUL). pp. 1 - 13. ISSN: 1664-3224 Open Access Link

Journal article

Safinia, N., Grageda, N., Scottá, C., Thirkell, S., Fry, LJ., Vaikunthanathan, T., et al. (2018) 'Cell therapy in organ transplantation: Our experience on the clinical translation of regulatory T cells'. Frontiers in Immunology, 9 (FEB). pp. 1 - 8. ISSN: 1664-3224 Open Access Link

Journal article

Fraser, H., Safinia, N., Grageda, N., Thirkell, S., Lowe, K., Fry, LJ., et al. (2018) 'A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials'. Molecular Therapy Methods and Clinical Development, 8. pp. 198 - 209. ISSN: 2329-0501 Open Access Link

Journal article

Cossarizza, A., Chang, HD., Radbruch, A., Akdis, M., Andrä, I., Annunziato, F., et al. (2017) 'Guidelines for the use of flow cytometry and cell sorting in immunological studies'. European Journal of Immunology, 47 (10). pp. 1584 - 1797. ISSN: 0014-2980

Journal article

Guggino, G., Scottà, C., Lombardi, G., DIeli, F. and Sireci, G. (2017) 'Invariant natural killer T cells treated with rapamycin or transforming growth factor-β acquire a regulatory function and suppress T effector lymphocytes'. Cellular and Molecular Immunology, 14 (4). pp. 392 - 394. ISSN: 1672-7681

Journal article

Canavan, JB., Scottà, C., Vossenkämper, A., Goldberg, R., Elder, MJ., Shoval, I., et al. (2016) 'Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease'. Gut, 65 (4). pp. 584 - 594. ISSN: 0017-5749

Journal article

Scottà, C., Fanelli, G., Hoong, SJ., Romano, M., Lamperti, EN., Sukthankar, M., et al. (2016) 'Impact of immunosuppressive drugs on the therapeutic efficacy of ex vivo expanded human regulatory T cells'. Haematologica, 101 (1). pp. 91 - 100. ISSN: 0390-6078

Journal article

Safinia, N., Scotta, C., Vaikunthanathan, T., Lechler, RI. and Lombardi, G. (2015) 'Regulatory T cells: Serious contenders in the promise for immunological tolerance in transplantation'. Frontiers in Immunology, 6 (AUG). pp. 438. ISSN: 1664-3224

Journal article

Edozie, FC., Nova-Lamperti, EA., Povoleri, GAM., Scottà, C., John, S., Lombardi, G. and et al. (2014) 'Regulatory T-cell therapy in the induction of transplant tolerance: The issue of subpopulations'. Transplantation, 98 (4). pp. 370 - 379. ISSN: 0041-1337

Journal article

Povoleri, GAM., Scottá, C., Nova-Lamperti, EA., John, S., Lombardi, G. and Afzali, B. (2013) 'Thymic versus induced regulatory T cells-who regulates the regulators?'. Frontiers in Immunology, 4 (JUN). pp. 169. ISSN: 1664-3224

Journal article

Scottà, C., Esposito, M., Fazekasova, H., Fanelli, G., Edozie, FC., Ali, N., et al. (2013) 'Differential effects of rapamycin and retinoic acid on expansion, stability and suppressive qualities of human CD4+CD25+FOXP3+ T regulatory cell subpopulations'. Haematologica, 98 (8). pp. 1291 - 1299. ISSN: 0390-6078

Journal article

Afzali, B., Mitchell, PJ., Edozie, FC., Povoleri, GAM., Dowson, SE., Demandt, L., et al. (2013) 'CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner'. European Journal of Immunology, 43 (8). pp. 2043 - 2054. ISSN: 0014-2980

Journal article

Afzali, B., Edozie, FC., Fazekasova, H., Scottà, C., Mitchell, PJ., Canavan, JB., et al. (2013) 'Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation.'. Clinical journal of the American Society of Nephrology : CJASN, 8 (8). pp. 1396 - 1405. ISSN: 1555-9041

Journal article

Canavan, JB., Afzali, B., Scottà, C., Fazekasova, H., Edozie, FC., Macdonald, TT., et al. (2012) 'A rapid diagnostic test for human regulatory T-cell function to enable regulatory T-cell therapy'. Blood, 119 (8). pp. e57 - e66. ISSN: 0006-4971

Journal article

Afzali, B., Mitchell, PJ., Scottà, C., Canavan, J., Edozie, FC., Fazekasova, H., et al. (2011) 'Relative resistance of human CD4 + memory T cells to suppression by CD4 +CD25 + regulatory T cells'. American Journal of Transplantation, 11 (8). pp. 1734 - 1742. ISSN: 1600-6135

Journal article

Lombardi, G., Sagoo, P., Scotta, C., Fazekasova, H., Smyth, L., Tsang, J., et al. (2011) 'Cell therapy to promote transplantation tolerance: A winning strategy?'. Immunotherapy, 3 (4 SUPPL.). pp. 28 - 31. ISSN: 1750-743X

Journal article

Scottà, C., Soligo, M., Camperio, C. and Piccolella, E. (2008) 'FOXP3 induced by CD28/B7 interaction regulates CD25 and anergic phenotype in human CD4+CD25- T lymphocytes'. Journal of Immunology, 181 (2). pp. 1025 - 1033. ISSN: 0022-1767

Journal article

Scottà, C., Garbuglia, AR., Ruggeri, L., Spada, E., Laurenti, L., Perrone, MP., et al. (2008) 'Influence of specific CD4+ T cells and antibodies on evolution of hypervariable region 1 during acute HCV infection'. Journal of Hepatology, 48 (2). pp. 216 - 228. ISSN: 0168-8278

Journal article

Scottà, C., Tuosto, L., Masci, AM., Racioppi, L., Piccolella, E. and Frasca, L. (2005) 'Hypervariable region 1 variant acting as TCR antagonist affects hepatitis C virus-specific CD4+ T cell repertoire by favoring CD95-mediated apoptosis'. Journal of Leukocyte Biology, 78 (2). pp. 372 - 382. ISSN: 0741-5400

Journal article

Riganò, R., Buttari, B., De Falco, E., Profumo, E., Ortona, E., Margutti, P., et al. (2004) 'Echinococcus granulosus-specific T-cell lines derived from patients at various clinical stages of cystic echinococcosis'. Parasite Immunology, 26 (1). pp. 45 - 52. ISSN: 0141-9838

Journal article

Frasca, L., Scottà, C., Del Porto, P., Nicosia, A., Pasquazzi, C., Versace, I., et al. (2003) 'Antibody-selected mimics of hepatitis C virus hypervariable region 1 activate both primary and memory Th lymphocytes'. Hepatology, 38 (3). pp. 653 - 663. ISSN: 0270-9139

Journal article

Frasca, L., Scottà, C., Lombardi, G. and Piccolella, E. (2003) 'Both maturation and survival of human dendritic cells are impaired in the presence of anergic/suppressor T cells'. Clinical and Developmental Immunology, 10 (1). pp. 61 - 65. ISSN: 1740-2522

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