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Dr Emma Bourton
Senior Lecturer (Education) in Biosciences
Heinz Wolff 232
- Email: emma.bourton@brunel.ac.uk
- Tel: +44 (0)1895 265343
Bourton, EC., Ahorner, PA., Plowman, PN., Zahir, SA., Al-Ali, H. and Parris, CN. (2017) 'The PARP-1 inhibitor Olaparib suppresses BRCA1 protein levels, increases apoptosis and causes radiation hypersensitivity in BRCA1+/- lymphoblastoid cells'. Journal of Cancer, 8 (19). pp. 4048 - 4056. ISSN: 1837-9664 Open Access Link
Zahir, SA., Plowman, PN., Bourton, EC., Sharif, F. and Parris, C. (2015) 'Increased gamma-H2AX and Rad51 DNA Repair Biomarker Expression in Human Cell Lines Resistant to the Chemotherapeutic Agents Nitrogen Mustard and Cisplatin.'. Chemotherapy, 60 (5). pp. 310 - 320. ISSN: 0009-3157 Open Access Link
Parris, CN., Zahir, SA., Al-Ali, H., Bourton, EC., Plowman, C. and Plowman, PN. (2015) 'Enhanced γ-H2AX DNA damage foci detection using multimagnification and extended depth of field in imaging flow cytometry'. Cytometry Part A, 87 (8). pp. 717 - 723. ISSN: 1552-4922 Open Access Link
Bourton, EC., Hussain, H., Plowman, PN., Harvey, AJ. and Parris, C. (2015) 'Radiosensitivity of Human Breast Cancer Cell Lines Expressing the Breast Tumor Kinase (Brk)'. Journal of Cancer Science and Therapy, 7 (3). pp. 95 - 101. ISSN: 1948-5956 Open Access Link
Payne, AM., Wilson, F., Bourton, E. and Stergioulas, L. (2015) '(Under review) Feedback in e-learning systems-what, when and how?'. Assessment and Evaluation in Higher Education. ISSN: 1469-297X
Bourton, EC., Foster, HA., Plowman, PN., Harvey, AJ. and Parris, CN. (2013) 'Hypersensitivity of BRCA1 Heterozygote Lymphoblastoid Cells to Gamma Radiation and PARP Inhibitors.'. J.Genet Syndr Gene Ther, 4 (5). pp. 146.Open Access Link
Bourton, EC., Plowman, PN., Harvey, AJ., Adam Zahir, S. and Parris, CN. (2013) 'The PARP-1 inhibitor Olaparib causes retention of γ-H2AX foci in BRCA1 heterozygote cells following exposure to gamma radiation'. Journal of Cancer Therapy, 4 (11a). pp. 44 - 52. ISSN: 2151-1934 Open Access Link
Ulus-Senguloglu, G., Arlett, CF., Plowman, PN., Parnell, J., Patel, N., Bourton, EC. and et al. (2012) 'Elevated expression of artemis in human fibroblast cells is associated with cellular radiosensitivity and increased apoptosis'. British Journal of Cancer, 107 (9). pp. 1506 - 1513. ISSN: 0007-0920 Open Access Link
Bourton, EC., Plowman, PN., Zahir, SA., Senguloglu, GU., Serrai, H., Bottley, G. and et al. (2012) 'Multispectral imaging flow cytometry reveals distinct frequencies of γ-H2AX foci induction in DNA double strand break repair defective human cell lines.'. Cytometry A, 81 (2). pp. 130 - 137. ISSN: 1552-4922 Open Access Link
Parris, CN., Bourton, EC. and Plowman, PN. (2012) 'Multispectral imaging flow cytometry reveals distinct frequencies of gamma-H2AX foci induction in DNA double strand break repair defective human cells lines'. MUTAGENESIS, 27 (1). pp. 132 - 132. ISSN: 0267-8357
Bourton, EC., Plowman, PN. and Parris, CN. (2012) 'Prolonged expression of the gamma-H2AX DNA repair biomarker correlates with excess acute and chronic toxicity from radiotherapy treatment'. MUTAGENESIS, 27 (1). pp. 109 - 109. ISSN: 0267-8357
Bourton, EC., Plowman, PN., Smith, D., Arlett, CF. and Parris, CN. (2011) 'Prolonged expression of the γ-H2AX DNA repair biomarker correlates with excess acute and chronic toxicity from radiotherapy treatment'. International Journal of Cancer, 129 (12). pp. 2928 - 2934. ISSN: 1097-0215 Open Access Link
Abbaszadeh, F., Clingen, PH., Arlett, CF., Plowman, PN., Bourton, EC., Themis, M., et al. (2010) 'A novel splice variant of the DNA-PKcs gene is associated with clinical and cellular radiosensitivity in a patient with xeroderma pigmentosum'. Journal of Medical Genetics, 47 (3). pp. 176 - 181. ISSN: 1468-6244
Bourton, E., Guan, YH., Sutherland, IA. and Fisher, D. (2009) 'Application led column design for protein separations in ATPS by countercurrent chromatography'.15th International Conference on Biopartitioning and Purification (BPP2009). Brunel University, Uxbridge, UK. 14 - 19 June. [unpublished]
Guan, YH., Bourton, EC., Hewitson, P., Sutherland, IA. and Fisher, D. (2009) 'The importance of column design for protein separation using aqueous two-phase systems on J-type countercurrent chromatography'. Separation and Purification Technology, 65 (1). pp. 79 - 85. ISSN: 1383-5866
Sutherland, IA., Audo, G., Bourton, E., Couillard, F., Fisher, D., Garrard, I., et al. (2008) 'Rapid linear scale-up of a protein separation by centrifugal partition chromatography'. Journal of Chromatography A, 1190 (1-2). pp. 57 - 62. ISSN: 0021-9673