CenGEM
Delaneau, O., Marchini, J., McVeanh, GA., Donnelly, P., Lunter, G., Marchini, JL., et al. (2014) 'Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel'. Nature Communications, 5 (1). pp. 3934. ISSN: 2041-1723 Open Access Link
Riverso, M., Kortenkamp, A. and Silva, E. (2014) 'Non-tumorigenic epithelial cells secrete MCP-1 and other cytokines that promote cell division in breast cancer cells by activating ERα via PI3K/Akt/mTOR signaling'. International Journal of Biochemistry and Cell Biology, 53. pp. 281 - 294. ISSN: 1357-2725 Open Access Link
Booth, DG., Takagi, M., Sanchez-Pulido, L., Petfalski, E., Vargiu, G., Samejima, K., et al. (2014) 'Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery'. eLife, 3 (3). pp. e01641. ISSN: 2050-084X Open Access Link
Mparmpakas, D., Zachariades, E., Sotiriadis, G., Goumenou, A., Harvey, AJ., Gidron, Y. and et al. (2014) 'Differential expression of placental glucocorticoid receptors and growth arrest-specific transcript 5 in term and preterm pregnancies: evidence for involvement of maternal stress'. Obstetrics and Gynecology International, 2014. pp. 1 - 10. ISSN: 1687-9589 Open Access Link
Motevalli, A., Yasaei, H., Virmouni, SA., Slijepcevic, P. and Roberts, T. (2014) 'The effect of chemotherapeutic agents on telomere length maintenance in breast cancer cell lines'. Breast Cancer Research and Treatment, 145 (3). pp. 581 - 591. ISSN: 0167-6806 Open Access Link
Schurbaji, K., Bagoanda, N., Ignatova, S., Fisher, D. and Themis, M. (2014) 'Rapid purification of 1st generation adenovirus vectors by aqueous two-phase system technology'.Annual Conference of the British-Society-for-Gene-and-Cell-Therapy (BSGCT). London, ENGLAND. 1 MARY ANN LIEBERT, INC. pp. A8 - A8. ISSN: 1043-0342
Davis, H., Lewis, A., Behrens, A. and Tomlinson, I. (2014) 'Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines'. Gut, 63 (5). pp. 792 - 799. ISSN: 0017-5749
Khonsari, H., Howe, S., Waddington, S., Pook, M. and Themis, M. (2014) 'An investigation to determine the efficacy of lentivirus-mediated FXN gene delivery for the correction of Friedreich ataxia'. HUMAN GENE THERAPY. pp. A10 - A10. ISSN: 1043-0342
Da Silva, DD., Silva, E., Carvalho, F. and Carmo, H. (2014) 'Mixtures of 3,4-methylenedioxymethamphetamine (ecstasy) and its major human metabolites act additively to induce significant toxicity to liver cells when combined at low, non-cytotoxic concentrations'. Journal of Applied Toxicology, 34 (6). pp. 618 - 627. ISSN: 0260-437X
Da Silva, DD., Silva, E. and Carmo, H. (2014) 'Combination effects of amphetamines under hyperthermia - the role played by oxidative stress'. Journal of Applied Toxicology, 34 (6). pp. 637 - 650. ISSN: 0260-437X
Iansante, V., Choy, PM., Fung, SW., Chai, J-G., Dyson, J., Liu, Y., et al. (2014) 'Upregulation of a novel protein in HCC enhances cancer cell survival by suppressing specific apoptotic effectors'.49th Annual International Liver Congress of the European-Association-for-the-Study-of-the-Liver. London, ENGLAND. 24 - 13 April. Elsevier BV. pp. S89 - S89. ISSN: 0168-8278 Open Access Link
Upton, AL., Grove, JI., Mahdi, AA., Briggs, GS., Milner, DS., Rudolph, CJ. and et al. (2014) 'Cellular location and activity of Escherichia coli RecG proteins shed light on the function of its structurally unresolved C-terminus'. Nucleic Acids Research, 42 (9). pp. 5702 - 5714. ISSN: 0305-1048 Open Access Link
Kortenkamp, A., Scholze, M. and Ermler, S. (2014) 'Mind the gap: Can we explain declining male reproductive health with known antiandrogens?'. Reproduction, 147 (4). pp. 515 - 527. ISSN: 1470-1626 Open Access Link
Ribeiro, SA., Vagnarelli, P. and Earnshaw, WC. (2014) 'DNA content of a functioning chicken kinetochore'. Chromosome Research, 22 (1). pp. 7 - 13. ISSN: 0967-3849 Open Access Link
Ermler, S., Scholze, M. and Kortenkamp, A. (2014) 'Genotoxic mixtures and dissimilar action: Concepts for prediction and assessment'. Archives of Toxicology, 88 (3). pp. 799 - 814. ISSN: 0340-5761 Open Access Link
Sandi, C., Sandi, M., Jassal, H., Ezzatizadeh, V., Anjomani-Virmouni, S., Al-Mahdawi, S. and et al. (2014) 'Generation and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell models'. PLoS One, 9 (2). pp. e89488 - e89488. ISSN: 1932-6203 Open Access Link
Scholze, M., Silva, E. and Kortenkamp, A. (2014) 'Extending the applicability of the dose addition model to the assessment of chemical mixtures of partial agonists by using a novel toxic unit extrapolation method'. PLoS ONE, 9 (2). pp. e88808 - e88808. ISSN: 1932-6203 Open Access Link
Osborn, DPS., Roccasecca, RM., McMurray, F., Hernandez-Hernandez, V., Mukherjee, S., Barroso, I., et al. (2014) 'Loss of FTO Antagonises Wnt Signaling and Leads to Developmental Defects Associated with Ciliopathies'. PLoS ONE, 9 (2). pp. e87662 - e87662. ISSN: 1932-6203 Open Access Link
Holmes, MV., Asselbergs, FW., Palmer, TM., Drenos, F., Lanktree, MB., Nelson, CP., et al. (2014) 'Mendelian randomization of blood lipids for coronary heart disease'. European Heart Journal, 36 (9). pp. 539 - 550. ISSN: 0195-668X Open Access Link
Bridger, JM., Arican-Gotkas, HD., Foster, HA., Godwin, LS., Harvey, A., Kill, IR., et al. (2014) 'The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer'. Advances in Experimental Medicine and Biology, 773. pp. 263 - 279. ISSN: 0065-2598 Open Access Link
Hussain, HA. and Harvey, A. (2014) 'Evolution of breast cancer therapeutics: Breast tumour kinase’s role in breast cancer and hope for breast tumour kinase targeted therapy'. World Journal of Clinical Oncology, 5 (3). pp. 299 - 310. ISSN: 2218-4333 Open Access Link
Condiotti, R., Goldenberg, D., Giladi, H., Schnitzer-Perlman, T., Waddington, SN., Buckley, SMK., et al. (2014) 'Transduction of fetal mice with a feline lentiviral vector induces liver tumors which exhibit an E2F activation signature'. Molecular Therapy, 22 (1). pp. 59 - 68. ISSN: 1525-0016 Open Access Link
Axelstad, M., Christiansen, S., Boberg, J., Scholze, M., Jacobsen, PR., Isling, LK., et al. (2014) 'Mixtures of endocrine-disrupting contaminants induce adverse developmental effects in preweaning rats'. Reproduction, 147 (4). pp. 489 - 501. ISSN: 1470-1626
Foster, HA., Davies, J., Pink, RC., Turkcigdem, S., Goumenou, A., Carter, DR., et al. (2014) 'The human myometrium differentially expresses mTOR signalling components before and during pregnancy: Evidence for regulation by progesterone'. Journal of Steroid Biochemistry and Molecular Biology, 139. pp. 166 - 172. ISSN: 0960-0760 Open Access Link
Isling, LK., Boberg, J., Jacobsen, PR., Mandrup, KR., Axelstad, M., Christiansen, S., et al. (2014) 'Late-life effects on rat reproductive system after developmental exposure to mixtures of endocrine disrupters'. Reproduction, 147 (4). pp. 465 - 476. ISSN: 1470-1626
Sandi, C., Sandi, M., Virmouni, SA., Al-Mahdawi, S. and Pook, MA. (2014) 'Epigenetic-based therapies for Friedreich ataxia'. Frontiers in Genetics, 5 (JUN). pp. 165. ISSN: 1664-8021 Open Access Link
Al-Mahdawi, S., Virmouni, SA. and Pook, MA. (2014) 'The emerging role of 5-hydroxymethylcytosine in neurodegenerative diseases'. Frontiers in Neuroscience, 8 (DEC). pp. 397. ISSN: 1662-4548 Open Access Link
Kamel, YM., Naiel, A., Alshehri, A., Saccone, S., Anderson, R. and Tosi, S. (2014) 'Fluorescence in situ hybridisation assays designed for del(7q) detection uncover more complex rearrangements in myeloid leukaemia cell lines'. Trends in Cancer Research, 10. pp. 17 - 26.Open Access Link
Ereku, LT., Mackay, RE., Ajayi, K. and Balachandran, W. (2014) 'Continuous flow pressure driven microfluidic techniques for point of care testing'. Sensors and Transducers, 170 (5). pp. 1 - 18.
Vagnarelli, P. (2014) 'Repo-man at the intersection of chromatin remodelling, DNA repair, nuclear envelope organization, and cancer progression'. Advances in Experimental Medicine and Biology, 773. pp. 401 - 414. ISSN: 0065-2598
Teles, J., Enver, T. and Pina, C. (2014) 'Single-cell PCR profiling of gene expression in hematopoiesis'. Methods in Molecular Biology, 1185. pp. 21 - 42. ISSN: 1064-3745
Bridger, JM., Arican-Gotkas, HD., Foster, HA., Godwin, LS., Harvey, A., Kill, IR., et al. (2014) 'The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer'. Advances in Experimental Medicine and Biology, 773. pp. 263 - 279. ISSN: 0065-2598
Wazir, U., Ahmad, MH., Bridger, JM., Harvey, A., Jiang, WG., Sharma, AK. and et al. (2013) 'Abstract P6-04-14: mRNA expressions of lamin B1 and lamin B receptor: Clinical correlations with human breast cancer'. American Association for Cancer Research (AACR). ISSN: 0008-5472
Höfken, T. (2013) 'Candida and candidiasis', in Kishore, U. and Nayak, A. (eds.) Microbial pathogenesis: Infection and immunity. New York : Springer Science+Business Media and Landes Bioscience. pp. 82 - 114. ISBN 13: 978-1-4614-9529-1.
Swiers, G., Baumann, C., O'Rourke, J., Giannoulatou, E., Taylor, S., Joshi, A., et al. (2013) 'Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level'. Nature Communications, 4 (1). pp. 2924. ISSN: 2041-1723
Ermler, S. (2013) 'State of the Art on Chemical Mixtures Research, invited lecture'.Chemical mixtures : challenges for research and risk assessment. Paris, France. 10 - 11 December. [unpublished]
May, G., Soneji, S., Tipping, AJ., Teles, J., McGowan, SJ., Wu, M., et al. (2013) 'Dynamic analysis of gene expression and genome-wide transcription factor binding during lineage specification of multipotent progenitors'. Cell Stem Cell, 13 (6). pp. 754 - 768. ISSN: 1934-5909
Sotiriadis, G., Kishore, U. and Karteris, E. (2013) 'Roles of innate immune molecules in pre-term birth'. IMMUNOLOGY. pp. 76 - 76. ISSN: 0019-2805
Dias Da Silva, D., Carmo, H., Lynch, A. and Silva, E. (2013) 'An insight into the hepatocellular death induced by amphetamines, individually and in combination: The involvement of necrosis and apoptosis'. Archives of Toxicology, 87 (12). pp. 2165 - 2185. ISSN: 0340-5761
Burugapalli, K., Wijesuriya, S., Messias, S., Mackay, R. and Balachandran, W. (2013) 'Progress of Surface Enhanced Raman Spectroscopy (SERS) for diagnostics and monitoring'.Optics in Clinical Practice II. Institute of Physics, London, UK.
Shtam, TA., Kovalev, RA., Varfolomeeva, EY., Makarov, EM., Kil, YV. and Filatov, MV. (2013) 'Exosomes are natural carriers of exogenous siRNA to human cells in vitro'. Cell Communication and Signaling, 11 (1). pp. 1 - 10. ISSN: 1478-811X Open Access Link
Meadows, JC., Graumann, K., Platani, M., Schweizer, N., Shimi, T., Vagnarelli, P. and et al. (2013) 'Meeting report: Mitosis and nuclear structure'. Journal of Cell Science, 126 (22). pp. 5087 - 5090. ISSN: 0021-9533
Payne, AM., Ghorbani, M., Taylor, S. and Pook, M. (2013) 'Comparative (Computational) Analysis of the DNA Methylation Status of Trinucleotide Repeat Expansion Diseases'. Journal of Nucleic Acids, 2013. pp. 1 - 9. ISSN: 2090-0201 Open Access Link
Gaunt, TR., Zabaneh, D., Shah, S., Guyatt, A., Ladroue, C., Kumari, M., et al. (2013) 'Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip'. Thrombosis and Haemostasis, 110 (5). pp. 995 - 1003. ISSN: 0340-6245
Harvey, A. (2013) 'Signalling Cross Talk', in Harvey, AJ. (ed.) Cancer Cell Signalling. Wiley Blackwell. pp. 193 - 206. ISBN 13: 978-1-119-96757-6.
Harvey, A. (2013) 'Cancer Cell Signalling'. Wiley Blackwell. ISSN 13: 978-1-119-96756-9
Ramanjaneya, M., Karteris, E., Chen, J., Rucinski, M., Ziolkowska, A., Ahmed, N., et al. (2013) 'QRFP induces aldosterone production via PKC and T-type calcium channel-mediated pathways in human adrenocortical cells: Evidence for a novel role of GPR103'. American Journal of Physiology - Endocrinology and Metabolism, 305 (9). pp. E1049 - E1058. ISSN: 0193-1849
Harvey, A. (2013) 'Epidermal Growth Factor Receptor Family', in Harvey, AJ. (ed.) Cancer Cell Signalling. Wiley Blackwell. pp. 1 - 24. ISBN 13: 978-1-119-96757-6.
Thorpe, M., Shehu, E. and Harvey, A. (2013) 'Insulin and the insulin like growth factor (IGF) family', in Harvey, AJ. (ed.) Cancer Cell Signalling. Wiley Blackwell. pp. 25 - 43. ISBN 13: 978-1-119-96757-6.
Martin, O., Kortenkamp, A. and Scholze, M. (2013) 'Safety factors in chemical risk assessment.'.Threshold of Toxicological Concern (TTC) for risk assessment of food contact material chemicals. Zurich, Switzerland. [unpublished]
Backhaus, T., Faust, M. and Kortenkamp, A. (2013) 'Cumulative risk assessment: a European perspective on the state of the art and the necessary next steps forward.'. Integrated environmental assessment and management, 9 (4). pp. 547 - 548. ISSN: 1551-3777