Professor Joanna Bridger
Professor
Heinz Wolff 107
- Email: joanna.bridger@brunel.ac.uk
- Tel: +44 (0)1895 266272
Bridger, JM. and Knight, M. (2024) 'Editorial: Gastropoda immunity and host-pathogen interactions'. Frontiers in Immunology, 15. pp. 1 - 2. ISSN: 1664-3224 Open Access Link
Garimberti, E., Federico, C., Ragusa, D., Bruno, F., Saccone, S., Bridger, JM. and et al. (2024) 'Alterations in Genome Organization in Lymphoma Cell Nuclei due to the Presence of the t(14;18) Translocation'. International Journal of Molecular Sciences, 25 (4). pp. 1 - 12. ISSN: 1661-6596 Open Access Link
Perira Torres, R., Samarakone, C., Bridger, J. and de Castro, I. (2024) 'Pushing the envelope - how the genome interacts with the nuclear envelope in health and disease.', in Donev, R. (ed.) ADVANCES IN PROTEIN CHEMISTRY AND STRUCTURAL BIOLOGY: Nuclear Proteins. Amsterdam : Elsevier.Open Access Link
Schirmer, EC. and Bridger, JM. (2023) 'Editorial: Is aberrant genome organization a cause or consequence of specific diseases?'. Frontiers in Cell and Developmental Biology, 11. pp. 1 - 2. ISSN: 2296-634X Open Access Link
Silahtaroglu, A., Bridger, JM. and Lei, EP. (2022) '3D genome organization'. Scientific Reports, 12 (1). pp. 1 - 2. ISSN: 2045-2322 Open Access Link
Bridger, JM., Torres Pereira, R., Pina, C., Tosi, S. and Lewis, A. (2022) 'Alterations to Genome Organisation in Stem Cells, their Differentiation and Associated Diseases', in Kloc, M. and Kubiak, JZ. (eds.) Nuclear, Chromosomal, and Genomic Architecture in Biology and Medicine. Cham, Switzerland : Springer. , 70. pp. 71 - 102. ISBN 10: 3-031-06573-5. ISBN 13: 978-3-031-06572-9. Open Access Link
Barravecchia, I., De Cesari, C., Forcato, M., Scebba, F., Pyankova, O., Bridger, J., et al. (2021) 'Microgravity and space radiation inhibit autophagy in human capillary endothelial cells, through either opposite or synergistic effects on specific molecular pathways'. Cellular and Molecular Life Sciences, 79 (1). pp. 1 - 29. ISSN: 1420-682X Open Access Link
Federico, C., Bruno, F., Ragusa, D., Clements, CS., Brancato, D., Henry, MP., et al. (2021) 'Chromosomal Rearrangements and Altered Nuclear Organization: Recent Mechanistic Models in Cancer'. Cancers, 13 (22). pp. 1 - 13. ISSN: 2072-6694 Open Access Link
Smith, M., Yadav, S., Fagunloye, OG., Pels, NA., Horton, DA., Alsultan, N., et al. (2021) 'Piwi silencing mechanism involving the retrotransposon nimbus orchestrates resistance to infection with schistosoma mansoni in the snail vector, biomphalaria glabrata'. PLoS Neglected Tropical Diseases, 15 (9). pp. 1 - 28. ISSN: 1935-2727 Open Access Link
Mehta, I., Riyahi, K., Torres Pereira, R., Meaburn, K., Figgitt, M., Kill, I., et al. (2021) 'Interphase Chromosomes in Replicative Senescence: chromosome positioning as a senescence biomarker and the lack of nuclear motor-driven chromosome repositioning in senescent cells.'. Frontiers in Cell and Developmental Biology, 9. pp. 1 - 18. ISSN: 2296-634X Open Access Link
Godwin, LS., Bridger, JM. and Foster, HA. (2021) 'Fluorescence in situ Hybridization on DNA Halo Preparations to reveal whole Chromosomes, Telomeres and Gene Loci'. Journal of Vizualized Experiments, 169 (169). pp. 1 - 22. ISSN: 1940-087X Open Access Link
Bridger, JM. and Foster, HA. (2021) 'Senescence and the Genome', in Iourov, I., Vorsanova, S. and Yurov, Y. (eds.) Human Interphase Chromosomes: Biomedical Aspects. Cham, Switzerland : Springer International Publishing. pp. 87 - 106. ISBN 13: 978-3-030-62531-3. Open Access Link
Almendáriz-Palacios, C., Gillespie, ZE., Janzen, M., Martinez, V., Bridger, JM., Harkness, TAA., et al. (2020) 'The Nuclear Lamina: Protein Accumulation Disease and Clearance'. Biomedicines, 8 (7). pp. 1 - 23. ISSN: 2227-9059 Open Access Link
Belak, ZR., Pickering, JA., Gillespie, ZE., Audette, G., Eramian, M., Mitchell, JA., et al. (2019) 'Genes responsive to rapamycin and serum deprivation are clustered on chromosomes and undergo re-organization within local chromatin environments.'. Biochemistry and Cell Biology, 98 (2). pp. 178 - 190. ISSN: 0829-8211 Open Access Link
Clements, CS., Bikkul, MU., Ofosu, W., Eskiw, C., Tree, D., Makarov, E., et al. (2019) 'Presence and distribution of progerin in HGPS cells is ameliorated by drugs that impact on the mevalonate and mTOR pathways'. Biogerontology, 20 (3). pp. 337 - 358. ISSN: 1389-5729 Open Access Link
Federico, C., Owoka, T., Ragusa, D., Sturiale, V., Caponnetto, D., Leotta, CG., et al. (2019) 'Deletions of Chromosome 7q Affect Nuclear Organization and HLXB9Gene Expression in Hematological Disorders'. Cancers, 11 (4). pp. 1 - 19. ISSN: 2072-6694 Open Access Link
Henry, MP., Hawkins, JR., Boyle, J. and Bridger, JM. (2019) 'The Genomic Health of Human Pluripotent Stem Cells: Genomic Instability and the Consequences on Nuclear Organization'. Frontiers in Genetics, 10 (JAN). pp. 1 - 20. ISSN: 1664-8021 Open Access Link
Barravecchia, I., De Cesari, C., Pyankova, O., Scebba, F., Pè, M., Forcato, M., et al. (2019) 'A comprehensive molecular and morphological study of the effects of space flight on human capillary endothelial cells: sample quality assessment and preliminary results'.39th ISGP Meeting & ESA Life Sciences Meeting. Noordwijk, Netherlands. 16 - 22 June. Frontiers Media SA. ISSN: 0160-9009 Open Access Link
Mehmet, B., Faragher, R., Worthington, G., Meinke, P., Kerr, A., Sammy, A., et al. (2018) 'Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform'. Genes, Chromosomes and Cancer, 58 (6). pp. 341 - 356. ISSN: 1045-2257 Open Access Link
Bridger, JM., Brindley, PJ. and Knight, M. (2018) 'The snail Biomphalaria glabrata as a model to interrogate the molecular basis of complex human diseases'. PLoS Neglected Tropical Diseases, 12 (8). pp. e0006552 - e0006552. ISSN: 1935-2727 Open Access Link
Bikkul, M., Clements, C., Godwin, L., Goldberg, M., Kill, I. and Bridger, JM. (2018) 'Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decrease DNA damage respectively, in Hutchinson–Gilford progeria syndrome fibroblasts'. Biogerontology, 19 (6). pp. 579 - 602. ISSN: 1389-5729 Open Access Link
Adema, CM., Hillier, LW., Jones, CS., Loker, ES., Knight, M., Minx, P., et al. (2017) 'Whole genome analysis of a schistosomiasis-transmitting freshwater snail (vol 8, 15451, 2017)'. NATURE COMMUNICATIONS, 8 (1). pp. 16153. ISSN: 2041-1723 Open Access Link
Owoka, T., Federico, C., Foster, H., Longo, AM., Saccone, S., Bridger, JM., et al. (2017) 'HLXB9 expression is independent from its nuclear gene positioning in breast cancer cells'. BIOMED CENTRAL LTD. ISSN: 1755-8166
Adema, CM., Hillier, LW., Jones, CS., Loker, ES., Knight, M., Minx, P., et al. (2017) 'Whole genome analysis of a schistosomiasis-transmitting freshwater snail'. NATURE COMMUNICATIONS, 8 (1). pp. 15451. ISSN: 2041-1723 Open Access Link
Kill, IR., Foster, H., Bridger, JM. and Pancholi, S. (2016) 'RECONSTRUCTION OF YOUNG AND AGED DERMIS IN CULTURE.'. [Poster]
Bridger, JM., Bikkul, U., Bourne, G., Clements, C., Kill, IR., Makarov, E. and et al. (2016) 'UNDERSTANDING AND TREATMENT OF HUTCHINSON-GILFORD PROGERIA SYNDROME, A MODEL FOR NORMAL AGING'. [Poster]
Mitta, G., Gourbal, B., Grunau, C., Knight, M., Bridger, JM. and Theron, A. (2016) 'The Compatibility between Biomphalaria glabrata snails and Schistosoma mansoni: An Increasingly Complex Puzzle'. Advances in Parasitology, 97. pp. 114 - 145. ISSN: 0065-308X Open Access Link
Clements, CS., Bikkul, U., Ahmed, MH., Foster, HA., Godwin, LS. and Bridger, JM. (2016) 'Visualizing the Spatial Relationship of the Genome with the Nuclear Envelope Using Fluorescence In Situ Hybridization', in Shackleton, S., Collas, P. and Schirmer, EC. (eds.) The Nuclear Envelope. New York, NY, USA : Humana Press. , 1411. pp. 387 - 406. ISBN 10: 1-4939-3530-5. ISBN 13: 978-1-4939-3528-4. Open Access Link
Knight, M., Ittiprasert, W., Arican-Goktas, HD. and Bridger, JM. (2016) 'Epigenetic modulation, stress and plasticity in susceptibility of the snail host, Biomphalaria glabrata, to Schistosoma mansoni infection'. International Journal for Parasitology, 46 (7). pp. 389 - 394. ISSN: 0020-7519 Open Access Link
Gillespie, ZE., Mackay, K., Sander, M., Trost, B., Dawicki, W., Wickramarathna, A., et al. (2016) 'Rapamycin reduces fibroblast proliferation without causing quiescence and induces STAT5A/ B-mediated cytokine production'. Nucleus, 6 (6). pp. 490 - 506. ISSN: 1949-1034 Open Access Link
Bridger, JM. (2015) 'The Potential of Human Artificial Chromosomes in Biomedicine-are they the ultimate vector for gene therapy treatments in the clinic?'.20th International Chromosome Conference (ICC). Univ Kent, Canterbury, ENGLAND. 1 - 4 September. SPRINGER. pp. 352 - 353. ISSN: 0967-3849 Open Access Link
Rinaldi, G., Yan, H., Nacif-Pimenta, R., Matchimakul, P., Bridger, J., Mann, V., et al. (2015) 'Cytometric analysis, genetic manipulation and antibiotic selection of the snail embryonic cell line Bge from Biomphalaria glabrata, the intermediate host of Schistosoma mansoni.'. International Journal of Parasitology, 45 (8). pp. 527 - 535. ISSN: 0020-7519 Open Access Link
Arican-Goktas, HD., Ittiprasert, W., Bridger, JM. and Knight, M. (2014) 'Differential spatial repositioning of activated genes in Biomphalaria glabrata snails infected with Schistosoma mansoni'. PLoS Neglected Tropical Diseases, 8 (9). pp. e3013 - e3013. ISSN: 1935-2735 Open Access Link
Knight, M., Arican-Goktas, HD., Ittiprasert, W., Odoemelam, EC., Miller, AN. and Bridger, JM. (2014) 'Schistosomes and snails: A molecular encounter'. Frontiers in Genetics, 5 (JUL). pp. 1 - 7. ISSN: 1664-8021 Open Access Link
Bridger, JM., Arican-Gotkas, HD., Foster, HA., Godwin, LS., Harvey, A., Kill, IR., et al. (2014) 'The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer'. Advances in Experimental Medicine and Biology, 773. pp. 263 - 279. ISSN: 0065-2598 Open Access Link
Bridger, JM., Arican-Gotkas, HD., Foster, HA., Godwin, LS., Harvey, A., Kill, IR., et al. (2014) 'The non-random repositioning of whole chromosomes and individual gene loci in interphase nuclei and its relevance in disease, infection, aging, and cancer'. Advances in Experimental Medicine and Biology, 773. pp. 263 - 279. ISSN: 0065-2598
Wazir, U., Ahmad, MH., Bridger, JM., Harvey, A., Jiang, WG., Sharma, AK. and et al. (2013) 'Abstract P6-04-14: mRNA expressions of lamin B1 and lamin B receptor: Clinical correlations with human breast cancer'. American Association for Cancer Research (AACR). ISSN: 0008-5472
Foster, HA., Estrada-Girona, G., Themis, M., Garimberti, E., Hill, MA., Bridger, JM. and et al. (2013) 'Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells'. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 756 (1-2). pp. 66 - 77. ISSN: 1383-5718 Open Access Link
Wazir, U., Sharma, AK., Mokbel, K., Ahmed, MH., Bridger, JM., Harvey, A. and et al. (2013) 'The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer'. Cellular and Molecular Biology Letters. pp. 1 - 17. ISSN: 1425-8153
Wazir, U., Sharma, AK., Mokbel, K., Ahmed, MH., Bridger, JM., Harvey, A. and et al. (2013) 'The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer'. Cellular and Molecular Biology Letters, 18 (4). pp. 1 - 17. ISSN: 1425-8153 Open Access Link
Bourne, G., Moir, C., Bikkul, MU., Ahmed Hassan, M., Eskiw, CH., Kill, I., et al. (2013) 'Interphase chromosome behavior in normal and diseased cells', in Yurov, Y., Vorsanova, SG. and Iourov, IY. (eds.) Human Interphase Chromosomes: the Biomedical Aspects. Springer. , 9781461465584. pp. 9 - 33. ISBN 10: 1461465575. ISBN 13: 9781461465577.
Adema, CM., Bayne, CJ., Bridger, JM., Knight, M., Loker, ES., Yoshino, TP. and et al. (2012) 'Will all scientists working on snails and the diseases they transmit please stand up?'. PLoS Neglected Tropical Diseases, 6 (12). pp. e1835 - e1835. ISSN: 1935-2735 Open Access Link
Foster, HA., Griffin, DK. and Bridger, JM. (2012) 'Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues'. BMC Cell Biology, 13 (1). pp. 30. ISSN: 1471-2121 Open Access Link
Themis, M., Garimberti, E., Estrada, GG., Arsuaga, J., Hill, M., Bridger, J. and et al. (2012) 'Relative proximity of chromosome territories influences chromosome exchange partners in radiation-induced chromosome rearrangements in primary human bronchial epithelial cells and in a small cell lung cancer cell line'. Netherlands. Elsevier BV. pp. 118 - 119. ISSN: 0267-8357
Bridger, JM. (2011) 'Chromobility: the rapid movement of chromosomes in interphase nuclei'. Biochemical Society Transactions, 39 (6). pp. 1747 - 1751. ISSN: 1470-8752 Open Access Link
Ittiprasert, W., Myers, J., Odoemelam, EC., Raghavan, N., Lewis, F., Bridger, JM. and et al. (2011) 'Advances in the genomics and proteomics of the freshwater intermediate snail host of Schistosoma mansoni, Biomphalaria glabrata', inBiomphalaria Snails and Larval Trematodes. Springer New York. pp. 191 - 213. ISBN 13: 9781441970275.
Arbenz, L., Bridger, JM., Foster, HA., Van der Heuvel, R., Han, T., Sutherland, IA. and et al. (2011) 'Stem cell separations and countercurrent chromatography'. [Poster] Exhibited at. 16th International Conference on Biopartitioning and Purification (BPP2011), Puerto Vallarta, Mexico 18 9 2011
Mehta, IS., Arican, HD., Eskiw, CH., Kill, IR. and Bridger, JM. (2011) 'Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford Progeria syndrome cells.'. Genome Biology: biology for the post-genomic era, 12 (8). pp. R74. ISSN: 1465-6906 Open Access Link
Mehta, I., Eskiw, C., Aricane, H., Kill, I. and Bridger, J. (2011) 'Farnesyltransferase inhibitor treatment restores chromosome territory positions and active chromosome dynamics in Hutchinson-Gilford Progeria syndrome cells.'. Genome Biology, 12 (8). ISSN: 1474-760X
Ballabio, E., Regan, R., Garimberti, E., Harbott, J., Bradtke, J., Teigler-Schlegel, A., et al. (2011) 'Genomic imbalances are confined to non-proliferating cells in paediatric patients with acute myeloid leukaemia and a normal or incomplete karyotype'. PLoS ONE, 6 (6). pp. e20607 - e20607. ISSN: 1932-6203 Open Access Link