
Professor Jose Gonzalez-Alonso
Professor - Exercise and Cardiovascular Physiology
Heinz Wolff 221
- Email: jose.gonzalez-alonso@brunel.ac.uk
- Tel: +44 (0)1895 267324
- Sport, Health and Exercise Sciences
- Department of Life Sciences
- College of Health, Medicine and Life Sciences
Bergeron, MF., Bahr, R., Bärtsch, P., Bourdon, L., Calbet, JAL., Carlsen, K., et al. (2012) 'International Olympic Committee consensus statement on thermoregulatory and altitude challenges for high-level athletes'. British Journal of Sports Medicine, 46 (11). pp. 770 - 779. ISSN: 0306-3674
Goodall, S., González-Alonso, J., Ali, L., Ross, EZ. and Romer, LM. (2012) 'Supraspinal fatigue after normoxic and hypoxic exercise in humans'. J Physiol, 590 (11). pp. 2767 - 2782. ISSN: 0022-3751
Laitano, O., Kalsi, KK., Pearson, J., Lotlikar, M., Reischak-Oliveira, AR. and González-Alonso, J. (2012) 'Effects of graded exercise-induced dehydration and rehydration on circulatory markers of oxidative stress across the resting and exercising human leg'. Eur J Appl Physiol, 112 (5). pp. 1937 - 1944. ISSN: 1439-6319
Jeppesen, TD., Vissing, J. and González-Alonso, J. (2012) 'Influence of erythrocyte oxygenation and intravascular ATP on resting and exercising skeletal muscle blood flow in humans with mitochondrial myopathy'. Mitochondrion, 12 (3). pp. 414 - 422. ISSN: 1567-7249
Kalsi, KK. and González-Alonso, J. (2012) 'Temperature-dependent release of ATP from human erythrocytes: Mechanism for the control of local tissue perfusion'. Exp Physiol, 97 (3). pp. 419 - 432. ISSN: 0958-0670
González-Alonso, J. (2012) 'Human thermoregulation and the cardiovascular system'. Experimental Physiology, 97 (3). pp. 340 - 346. ISSN: 0958-0670
Jeppesen, TD., Vissing, J. and González-Alonso, J. (2012) 'Influence of erythrocyte oxygenation and intravascular ATP on resting and exercising skeletal muscle blood flow in humans with mitochondrial myopathy'. Mitochondrion, 12 (3). pp. 414 - 422. ISSN: 1567-7249
Stöhr, EJ., González-Alonso, J., Pearson, J., Low, DA., Ali, L., Barker, H. and et al. (2011) 'Dehydration reduces left ventricular filling at rest and during exercise independent of twist mechanics'. J Appl Physiol, 111 (3). pp. 891 - 897. ISSN: 8750-7587
Stöhr, EJ., González-Alonso, J. and Shave, R. (2011) 'Left ventricular mechanical limitations to stroke volume in healthy humans during incremental exercise'. American Journal of Physiology - Heart and Circulatory Physiology, 301 (2). pp. H478 - H487. ISSN: 0363-6135
Boushel, R., Gnaiger, E., Calbet, JAL., Gonzalez-Alonso, J., Wright-Paradis, C., Sondergaard, H., et al. (2011) 'Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans'. Mitochondrion, 11 (2). pp. 303 - 307. ISSN: 1567-7249
Pearson, J., Low, DA., Stöhr, E., Kalsi, K., Ali, L., Barker, H. and et al. (2011) 'Hemodynamic responses to heat stress in the resting and exercising human leg: insight into the effect of temperature on skeletal muscle blood flow'. Am J Physiol Regul Integr Comp Physiol, 300 (3). pp. R663 - R673. ISSN: 0363-6119
Stöhr, EJ., González-Alonso, J., Pearson, J., Low, DA., Ali, L., Barker, H. and et al. (2011) 'Effects of graded heat stress on global left ventricular function and twist mechanics at rest and during exercise in healthy humans'. Exp Physiol, 96 (2). pp. 114 - 124. ISSN: 1469-445X
Boushel, R., Gnaiger, E., Calbet, JAL., Gonzalez-Alonso, J., Wright-Paradis, C., Sondergaard, H., et al. (2011) 'Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans'. Mitochondrion, 11 (2). pp. 303 - 307. ISSN: 1567-7249
Dufour, SP., Patel, RP., Brandon, A., Teng, X., Pearson, J., Barker, H., et al. (2010) 'Erythrocyte dependent regulation of human skeletal muscle blood flow: role of varied oxyhemoglobin and exercise on nitrite, S-nitrosohemoglobin and ATP'. American Journal of Physiology, Heart and Circulation Physiology, 299 (6). pp. H1936 - H1946. ISSN: 0363-6135
Dufour, SP., Patel, RP., Brandon, A., Teng, X., Pearson, J., Barker, H., et al. (2010) 'Erythrocyte-dependent regulation of human skeletal muscle blood flow: role of varied oxyhemoglobin and exercise on nitrite, S-nitrosohemoglobin, and ATP.'. Am J Physiol Heart Circ Physiol, 299 (6). pp. H1936 - H1946. ISSN: 0363-6135
Grantham, J., Cheung, SS., Connes, P., Febbraio, MA., Gaoua, N., González-Alonso, J., et al. (2010) 'Current knowledge on playing football in hot environments'. Scandinavian Journal of Medicine and Science in Sports, 20 (SUPPL. 3). pp. 161 - 167. ISSN: 0905-7188
Crandall, CG. and González-Alonso, J. (2010) 'Cardiovascular function in the heat-stressed human'. Acta Physiologica, 199 (4). pp. 407 - 423. ISSN: 1748-1708
Laitano, O., Kalsi, KK., Pook, M., Oliveira, AR. and González-Alonso, J. (2010) 'Separate and combined effects of heat stress and exercise on circulatory markers of oxidative stress in euhydrated humans'. European Journal of Applied Physiology, 110 (5). pp. 953 - 960. ISSN: 1439-6327
Laitano, O., Kalsi, KK., Pook, M., Oliveira, AR. and González-Alonso, J. (2010) 'Separate and combined effects of heat stress and exercise on circulatory markers of oxidative stress in euhydrated humans'. European Journal of Applied Physiology. pp. 1 - 8. ISSN: 1439-6327
Mortensen, SP., González-Alonso, J., Nielsen, JJ., Saltin, B. and Hellsten, Y. (2009) 'Muscle interstitial ATP and norepinephrine concentrations in the human leg during exercise and ATP infusion'. J Appl Physiol, 107 (6). pp. 1757 - 1762. ISSN: 1522-1601
Mortensen, SP., González-Alonso, J., Bune, LT., Saltin, B., Pilegaard, H. and Hellsten, Y. (2009) 'ATP-induced vasodilation and purinergic receptors in the human leg: roles of nitric oxide, prostaglandins, and adenosine'. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, 296 (4). pp. R1140 - R1148. ISSN: 0363-6119
González-Alonso, J. and Mortensen, SP. (2009) 'Comments on point: counterpoint: Maximal oxygen uptake is/is not limited by a central nervous system governor'. Journal of Applied Physiology, 106 (1). pp. 344 - 345. ISSN: 8750-7587
González-Alonso, J. (2008) 'ATP: a double-edged signalling molecule regulating the flow of oxygen'. Journal of Physiology, 586 (17). pp. 4033 - 4034. ISSN: 1469-7793
Rosenmeier, JB., Yegutkin, GG. and González-Alonso, J. (2008) 'Activation of ATP/UTP-selective receptors increases blood flow and blunts sympathetic vasoconstriction in human skeletal muscle'. J Physiol, 586 (20). pp. 4993 - 5002. ISSN: 1469-7793
Mortensen, SP., Damsgaard, R., Dawson, EA., Secher, NH. and González-Alonso, J. (2008) 'Restrictions in systemic and locomotor skeletal muscle perfusion, oxygen supply and VO2 during high-intensity whole-body exercise in humans'. J Physiol, 586 (10). pp. 2621 - 2635. ISSN: 1469-7793
González-Alonso, J., Mortensen, SP., Jeppesen, TD., Ali, L., Barker, H., Damsgaard, R., et al. (2008) 'Haemodynamic responses to exercise, ATP infusion and thigh compression in humans: insight into the role of muscle mechanisms on cardiovascular function'. J Physiol, 586 (9). pp. 2405 - 2417. ISSN: 1469-7793
Mourtzakis, M., Graham, TE., González-Alonso, J. and Saltin, B. (2008) 'Glutamate availability is important in intramuscular amino acid metabolism and TCA cycle intermediates but does not affect peak oxidative metabolism'. Journal of Applied Physiology, 105 (2). pp. 547 - 554. ISSN: 8750-7587
González-Alonso, J. (2008) 'Last word on point: counterpoint: Stroke volume does/does not decline during exercise at maximal effort in healthy individuals (Letter to the editor)'. Journal of Applied Physiology, 104 (1). pp. 284. ISSN: 8750-7587
González-Alonso, J., Eiken, O. and Mekjavic, IB. (2008) 'A critical core temperature and the significance of absolute work rate', in Taylor, NAS. and Groeller, H. (eds.) Physiological Bases of Human Performance During Work and Exercise. Churchill Livingstone. pp. 481 - 485. ISBN 10: 0443102716. ISBN 13: 978-0443102714.
González-Alonso, J., Crandall, CG. and Johnson, JM. (2007) 'The cardiovascular challenge of exercising in the heat'. Journal of Physiology, 586 (1). pp. 45 - 53. ISSN: 0022-3751
Calbet, JAL., Gonzalez-Alonso, J., Helge, JW., Søndergaard, H., Munch-Andersen, T., Boushe, R. and et al. (2007) 'Cardiac output and leg and arm blood flow during incremental exercise to exhaustion on the cycle ergometer'. Journal of Applied Physiology, 103 (3). pp. 969 - 978. ISSN: 8750-7587
Juel, C., Olsen, S., Rentsch, RL., González-Alonso, J. and Rosenmeier, JB. (2007) 'K+ as a vasodilator in resting human muscle: Implications for exercise hyperaemia'. Acta Physiologica, 190 (4). pp. 311 - 318. ISSN: 1748-1708
Mortensen, SP., González-Alonso, J., Damsgaard, R., Saltin, B. and Hellsten, Y. (2007) 'Inhibition of nitric oxide and prostaglandins, but not endothelial-derived hyperpolarizing factors, reduces blood flow and aerobic energy turnover in the exercising human leg'. Journal of Physiology, 581 (2). pp. 853 - 861. ISSN: 0022-3751
Yegutkin, GG., Samburski, SS., Mortensen, SP., Jalkanen, S. and González-Alonso, J. (2007) 'Intravascular ADP and soluble nucleotidases contribute to acute prothrombotic state during vigorous exercise in humans'. J Physiol, 579 (2). pp. 553 - 564. ISSN: 0022-3751
González-Alonso, J. (2007) 'Hyperthermia impairs brain, heart and muscle function in exercising humans'. Sports Medicine, 37 (4-5). pp. 371 - 373. ISSN: 0112-1642
Damsgaard, R., Munch, T., Morkeberg, J., Mortensen, SP. and Gonzalez-Alonso, J. (2006) 'Effects of blood withdrawal and reinfusion on biomarkers of erythropoiesis in humans: Implications for anti-doping strategies'. Haematologica: the hematology journal, 91 (7). pp. 1006 - 1008. ISSN: 1592-8721
Damsgaard, R., Munch, T., Morkeberg, J., Mortensen, SP. and Gonzalez-Alonso, J. (2006) 'Effects of blood withdrawal and reinfusion on biomarkers of erythropoiesis in humans: Implications for anti-doping strategies'. HAEMATOLOGICA, 91 (7). pp. 1006 - 1008. ISSN: 0390-6078
González-Alonso, J., Mortensen, SP., Dawson, EA., Secher, NH. and Damsgaard, R. (2006) 'Erythrocytes and the regulation of human skeletal muscle blood flow and oxygen delivery: role of erythrocyte count and oxygenation state of haemoglobin.'. J Physiol, 572 (1). pp. 295 - 305. ISSN: 0022-3751
Marcuello, A., González-Alonso, J., Calbet, JAL., Damsgaard, R., López-Pérez, MJ. and Díez-Sánchez, C. (2005) 'Skeletal muscle mitochondrial DNA content in exercising humans'. Journal of Applied Physiology, 99 (4). pp. 1372 - 1377. ISSN: 8750-7587
Mortensen, SP., Dawson, EA., Yoshiga, CC., Dalsgaard, MK., Damsgaard, R., Secher, NH. and et al. (2005) 'Limitations to systemic and locomotor limb muscle oxygen delivery and uptake during maximal exercise in humans'. Journal of Physiology, 566 (1). pp. 273 - 285. ISSN: 0022-3751
Mourtzakis, M., González-Alonso, J., Graham, TE. and Saltin, B. (2004)
'Hemodynamics and O
Dawson, EA., Secher, NH., Dalsgaard, MK., Ogoh, S., Yoshiga, CC., González-Alonso, J., et al. (2004) 'Standing up to the challenge of standing: A siphon does not support cerebral blood flow in humans'. AJP - Regulatory, Integrative and Comparative Physiology, 287 (4). pp. R911 - R914. ISSN: 0363-6119
Krustrup, P., Söderlund, K., Mohr, M., González-Alonso, J. and Bangsbo, J. (2004) 'Recruitment of fibre types and quadriceps muscle portions during repeated, intense knee-extensor exercise in humans'. Pflugers Arch, 449 (1). pp. 56 - 65. ISSN: 0031-6768
Rosenmeier, JB., Hansen, J. and González-Alonso, J. (2004) 'Circulating ATP-induced vasodilatation overrides sympathetic vasoconstrictor activity in human skeletal muscle'. J Physiol, 558 (1). pp. 351 - 365. ISSN: 0022-3751
González-Alonso, J., Dalsgaard, MK., Osada, T. and Volianitis, S. (2004) 'Brain and central haemodynamics and oxygenation during maximal exercise in humans'. J Physiol, 557 (1). pp. 331 - 342. ISSN: 0022-3751
Hanada, A., Sander, M. and González-Alonso, J. (2003) 'Human skeletal muscle sympathetic nerve activity, heart rate and limb haemodynamics with reduced blood oxygenation and exercise.'. Journal of Physiology, 551 (2). pp. 635 - 647. ISSN: 0022-3751
González-Alonso, J. and Calbet, JAL. (2003) 'Reductions in systemic and skeletal muscle blood flow and oxygen delivery limit maximal aerobic capacity in humans'. Circulation, 107 (6). pp. 824 - 830. ISSN: 1524-4539
Gibala, MJ., González-Alonso, J. and Saltin, B. (2002) 'Dissociation between muscle tricarboxylic acid cycle pool size and aerobic energy provision during prolonged exercise in humans'. Journal of Physiology, 545 (2). pp. 705 - 713. ISSN: 0022-3751
González-Alonso, J., Olsen, DB. and Saltin, B. (2002) 'Erythrocyte and the regulation of human skeletal muscle blood flow and oxygen delivery - Role of circulating ATP'. Circ Res, 91 (11). pp. 1046 - 1055. ISSN: 0009-7330
Richardson, RS., Noyszewski, EA., Saltin, B. and González-Alonso, J. (2002) 'Effect of mild carboxy-hemoglobin on exercising skeletal muscle: intravascular and intracellular evidence'. Am J Physiol Regul Integr Comp Physiol, 283 (5). pp. R1131 - R1139. ISSN: 0363-6119
Bangsbo, J., Gibala, MJ., Krustrup, P., González-Alonso, J. and Saltin, B. (2002) 'Enhanced pyruvate dehydrogenase activity does not affect muscle O2 uptake at onset of intense exercise in humans.'. Am J Physiol Regul Integr Comp Physiol, 282 (1). pp. R273 - R280. ISSN: 0363-6119