Termination of DNA replication - a novel threat to genome stability and cell cycle control
Funder: BBSRCDuration: October 2013 - October 2016
People
| Name | Telephone | Office | ||
|---|---|---|---|---|
|
Dr Christian Rudolph Reader (Principal investigator)
T: +44 (0)1895 265372
E: christian.rudolph@brunel.ac.uk |
+44 (0)1895 265372 | christian.rudolph@brunel.ac.uk | Heinz Wolff 112 |
Outputs
Syeda, A., Dimude, J., Skovgaard, O. and Rudolph, C. (2020) 'Too much of a good thing: how ectopic DNA replication affects bacterial replication dynamics'. Frontiers in Microbiology, 11. pp. 1 - 21. ISSN: 1664-302X Open Access Link
Hawkins, M., Dimude, JU., Howard, JAL., Smith, AJ., Dillingham, MS., Savery, NJ., et al. (2019) 'Direct removal of RNA polymerase barriers to replication by accessory replicative helicases'. Nucleic Acids Research, 47 (10). pp. 5100 - 5113. ISSN: 0305-1048 Open Access Link
Midgley-Smith, S., Dimude, J. and Rudolph, C. (2018) 'A role for 3’ exonucleases at the final stages of chromosome duplication in Escherichia coli'. Nucleic Acids Research, 47 (4). pp. 1847 - 1860. ISSN: 0305-1048 Open Access Link
Dimude, JU., Midgley-Smith, SL. and Rudolph, CJ. (2018) 'Replication-transcription conflicts trigger extensive DNA degradation in Escherichia coli cells lacking RecBCD'. Mutation Research/DNA Repair, 70. pp. 37 - 48. ISSN: 0921-8777 Open Access Link
Dimude, JU., Stein, M., Andrzejewska, EE., Khalifa, MS., Gajdosova, A., Retkute, R., et al. (2018) 'Origins Left, Right, and Centre: Increasing the Number of Initiation Sites in the Escherichia coli Chromosome'. Genes, 9 (8). pp. 1 - 21. ISSN: 2073-4425 Open Access Link
Midgley-Smith, SL., Dimude, JU., Taylor, T., Forrester, NM., Upton, AL., Lloyd, RG. and et al. (2018) 'Chromosomal over-replication in Escherichia coli recG cells is triggered by replication fork fusion and amplified if replichore symmetry is disturbed'. Nucleic Acids Research, 46 (15). pp. 7701 - 7715. ISSN: 0305-1048 Open Access Link
Dimude, JU., Midgley-Smith, SL., Stein, M. and Rudolph, C. (2016) 'Replication Termination: Containing Fork Fusion-Mediated Pathologies in Escherichia coli'. Genes, 7 (8). pp. 40 - 40. ISSN: 2073-4425 Open Access Link
Lloyd, RG. and Rudolph, CJ. (2016) '25 years on and no end in sight: a perspective on the role of RecG protein.'. Current Genetics, 62 (4). pp. 827 - 840. ISSN: 0172-8083 Open Access Link
Dimude, JU., Stockum, A., Midgley-Smith, SL., Upton, AL., Foster, HA., Khan, A., et al. (2015) 'The consequences of replicating in the wrong orientation: bacterial chromosome duplication without an active replication origin'. mBio, 6 (6). pp. e01294 - e01215. ISSN: 2150-7511 Open Access Link
Ivanova, D., Taylor, T., Smith, SL., Dimude, JU., Upton, AL., Mehrjouy, M., et al. (2015) 'Shaping the landscape of the Escherichia coli chromosome: replication-transcription encounters in cells with an ectopic replication origin'. Nucleic Acids Research, 43 (16). pp. 7865 - 7877. ISSN: 1362-4962 Open Access Link