Protein Phosphatase 1 (PP1) in the regulation of mitotic exit and nuclear organisation
Funder: BBSRCDuration: October 2013 - September 2016
People
Name | Telephone | Office | ||
---|---|---|---|---|
Professor Paola Vagnarelli Professor - Cell Biology (Principal investigator)
T: +44 (0)1895 265025
E: paola.vagnarelli@brunel.ac.uk |
+44 (0)1895 265025 | paola.vagnarelli@brunel.ac.uk | Heinz Wolff 106 |
Outputs
Vagnarelli, P. and Alessi, D. (2018) 'PP1 Phosphatase Complexes: Undruggable No Longer'. Cell, 174 (5). pp. 1049 - 1051. ISSN: 1097-4172 Open Access Link
Sales Gil, R. and Vagnarelli, P. (2018) 'Ki-67: More Hidden behind a ‘Classic Proliferation Marker'. Trends in Biochemical Sciences, 43 (10). pp. 747 - 748. ISSN: 0968-0004 Open Access Link
Sales Gil, R. and Vagnarelli, P. (2018) 'Protein Phosphatases in chromatin structure and function'. BBA Molecular Cell Research, 1886 (1). pp. 90 - 101. ISSN: 0167-4889 Open Access Link
Sales Gil, R., de Castro, IJ., Berihun, J. and Vagnarelli, P. (2018) 'Protein Phosphatases at the Nuclear Envelope'. Biochemical Society Transactions, 46 (1). pp. 173 - 182. ISSN: 0300-5127 Open Access Link
de Castro, IJ., Sales Gil, R., Ligammari, L., Di Giacinto, ML. and Vagnarelli, P. (2017) 'CDK1 and PLK1 co-ordinate the disassembly and re-assembly of the Nuclear Envelope in vertebrate mitosis'. Oncotarget, 9 (8). pp. 7763 - 7773. ISSN: 1949-2553 Open Access Link
De Castro, IJ., Amin, HA., Vinciotti, V. and Vagnarelli, P. (2017) 'Network of phosphatases and HDAC complexes at repressed chromatin'. Cell Cycle, 16 (21). pp. 2011 - 2017. ISSN: 1538-4101 Open Access Link
Zhiteneva, A., Bonfiglio, J., Makarov, A., Colby, T., Vagnarelli, P., Schirmer, E., et al. (2017) 'Mitotic post-translational modifications of histones promote chromatin compaction in vitro'. Open Biology, 7 (9). pp. 170076 - 170076. ISSN: 2046-2441 Open Access Link
Martin, C-A., Murray, JE., Carroll, P., Leitch, A., MacKenzie, KJ., Halachev, M., et al. (2017) 'Corrigendum: Mutations in genes encoding condensins cause microcephaly through decatenation failure at mitosis'. Genes & Development, 31 (9). pp. 953 - 953. ISSN: 0890-9369
Castro, IJ., Budzak, J., Di Giacinto, ML., Ligammari, L., Gokhan, E., Spanos, C., et al. (2017) 'Repo-Man/PP1 regulates heterochromatin formation in interphase'. Nature Communications, 8 (1). pp. 14048. ISSN: 2041-1723 Open Access Link
Martin, C-A., Murray, JE., Carroll, P., Leitch, A., Mackenzie, KJ., Halachev, M., et al. (2016) 'Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis'. Genes & Development, 30 (19). pp. 2158 - 2172. ISSN: 0890-9369 Open Access Link
Ganesan, K., Gokhan, E., De Munter, S., Bollen, M., Vagnarelli, P., Peti, W. and et al. (2016) 'The Ki-67 and Repoman mitotic phosphatases assemble via an identical, yet novel mechanism'. eLife, 5 (AUGUST). pp. e16539. ISSN: 2050-084X Open Access Link
de Castro, IJ., Gokhan, E. and Vagnarelli, P. (2016) 'Resetting a functional G1 nucleus after mitosis'. Chromosoma, 125 (4). pp. 607 - 619. ISSN: 0009-5915 Open Access Link
Castro, I., Budzak, J., Di Giacinto, ML. and Vagnarelli, P. (2015) 'Repo-Man as a chromatin organiser in the interphase nuclei'.Gordon Reseach conference on Genome Architecture in Cell Fate & Disease. Hong Kong. 7 - 12 June.Open Access Link
Budzak, JD., Castro, I., Di Giacinto, ML. and Vagnarelli, P. (2015) 'Repo-Man is a multifunctional protein that regulates heterochromatin assembly and structure'.20th International Chromosome Conference (ICC). Univ Kent, Canterbury, ENGLAND. 1 - 4 September. SPRINGER. pp. 373 - 373. ISSN: 0967-3849
Booth, DG., Petfalsk, E., Tollervey, D., Earnshaw, WC. and Vagnarelli, P. (2015) 'Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery'.20th International Chromosome Conference (ICC). Univ Kent, Canterbury, ENGLAND. 1 - 4 September. SPRINGER. pp. 373 - 373. ISSN: 0967-3849
Gokhan, E., Page, R., Peti, W. and Vagnarelli, P. (2015) 'The Repo-Mann/PP1 complex structure and regulation'.20th International Chromosome Conference (ICC). Univ Kent, Canterbury, ENGLAND. 1 - 4 September. SPRINGER. pp. 387 - 388. ISSN: 0967-3849
Booth, DG., Takagi, M., Sanchez-Puilido, L., Petfalski, E., Vargiu, G., Samejima, K., et al. (2014) 'Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery.'.ASCB/IFCB Meeting. Philadelphia, PA. 1 - 10 December. AMER SOC CELL BIOLOGY. pp. 373 - 373. ISSN: 1059-1524
Castro, I., Budzak, J., Di Giacinto, ML., Foster, H., Reynolds, A., Ullman, KS. and et al. (2014) 'Repo-Man is a repressive chromatin modulator in the interphase nuclei'.ASCB/IFCB Meeting. Philadelphia, PA. 1 - 10 December. AMER SOC CELL BIOLOGY. ISSN: 1059-1524
Booth, DG., Takagi, M., Sanchez-Pulido, L., Petfalski, E., Vargiu, G., Samejima, K., et al. (2014) 'Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery'. eLife, 3 (3). pp. e01641. ISSN: 2050-084X Open Access Link
Vagnarelli, P. (2014) 'Repo-man at the intersection of chromatin remodelling, DNA repair, nuclear envelope organization, and cancer progression'. Advances in Experimental Medicine and Biology, 773. pp. 401 - 414. ISSN: 0065-2598
Meadows, JC., Graumann, K., Platani, M., Schweizer, N., Shimi, T., Vagnarelli, P. and et al. (2013) 'Meeting report: Mitosis and nuclear structure'. Journal of Cell Science, 126 (22). pp. 5087 - 5090. ISSN: 0021-9533