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Protein Phosphatase 1 (PP1) in the regulation of mitotic exit and nuclear organisation

Funder: BBSRC
Duration: October 2013 - September 2016

People

Name Telephone Email Office
Professor Paola Vagnarelli Professor Paola Vagnarelli
Professor - Cell Biology
(Principal investigator)
T: +44 (0)1895 265025
E: paola.vagnarelli@brunel.ac.uk
+44 (0)1895 265025 paola.vagnarelli@brunel.ac.uk Heinz Wolff 106

Outputs

Vagnarelli, P. and Alessi, D. (2018) 'PP1 Phosphatase Complexes: Undruggable No Longer'. Cell, 174 (5). pp. 1049 - 1051. ISSN: 1097-4172 Open Access Link

Journal article

Sales Gil, R. and Vagnarelli, P. (2018) 'Ki-67: More Hidden behind a ‘Classic Proliferation Marker'. Trends in Biochemical Sciences, 43 (10). pp. 747 - 748. ISSN: 0968-0004 Open Access Link

Journal article

Sales Gil, R. and Vagnarelli, P. (2018) 'Protein Phosphatases in chromatin structure and function'. BBA Molecular Cell Research, 1886 (1). pp. 90 - 101. ISSN: 0167-4889 Open Access Link

Journal article

Sales Gil, R., de Castro, IJ., Berihun, J. and Vagnarelli, P. (2018) 'Protein Phosphatases at the Nuclear Envelope'. Biochemical Society Transactions, 46 (1). pp. 173 - 182. ISSN: 0300-5127 Open Access Link

Journal article

de Castro, IJ., Sales Gil, R., Ligammari, L., Di Giacinto, ML. and Vagnarelli, P. (2017) 'CDK1 and PLK1 co-ordinate the disassembly and re-assembly of the Nuclear Envelope in vertebrate mitosis'. Oncotarget, 9 (8). pp. 7763 - 7773. ISSN: 1949-2553 Open Access Link

Journal article

De Castro, IJ., Amin, HA., Vinciotti, V. and Vagnarelli, P. (2017) 'Network of phosphatases and HDAC complexes at repressed chromatin'. Cell Cycle, 16 (21). pp. 2011 - 2017. ISSN: 1538-4101 Open Access Link

Journal article

Zhiteneva, A., Bonfiglio, J., Makarov, A., Colby, T., Vagnarelli, P., Schirmer, E., et al. (2017) 'Mitotic post-translational modifications of histones promote chromatin compaction in vitro'. Open Biology, 7 (9). pp. 170076 - 170076. ISSN: 2046-2441 Open Access Link

Journal article

Martin, C-A., Murray, JE., Carroll, P., Leitch, A., MacKenzie, KJ., Halachev, M., et al. (2017) 'Corrigendum: Mutations in genes encoding condensins cause microcephaly through decatenation failure at mitosis'. Genes & Development, 31 (9). pp. 953 - 953. ISSN: 0890-9369

Journal article

Castro, IJ., Budzak, J., Di Giacinto, ML., Ligammari, L., Gokhan, E., Spanos, C., et al. (2017) 'Repo-Man/PP1 regulates heterochromatin formation in interphase'. Nature Communications, 8 (1). pp. 14048. ISSN: 2041-1723 Open Access Link

Journal article

Martin, C-A., Murray, JE., Carroll, P., Leitch, A., Mackenzie, KJ., Halachev, M., et al. (2016) 'Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis'. Genes & Development, 30 (19). pp. 2158 - 2172. ISSN: 0890-9369 Open Access Link

Journal article

Ganesan, K., Gokhan, E., De Munter, S., Bollen, M., Vagnarelli, P., Peti, W. and et al. (2016) 'The Ki-67 and Repoman mitotic phosphatases assemble via an identical, yet novel mechanism'. eLife, 5 (AUGUST). pp. e16539. ISSN: 2050-084X Open Access Link

Journal article

de Castro, IJ., Gokhan, E. and Vagnarelli, P. (2016) 'Resetting a functional G1 nucleus after mitosis'. Chromosoma, 125 (4). pp. 607 - 619. ISSN: 0009-5915 Open Access Link

Journal article

Castro, I., Budzak, J., Di Giacinto, ML. and Vagnarelli, P. (2015) 'Repo-Man as a chromatin organiser in the interphase nuclei'.Gordon Reseach conference on Genome Architecture in Cell Fate & Disease. Hong Kong. 7 - 12 June.Open Access Link

Conference paper

Budzak, JD., Castro, I., Di Giacinto, ML. and Vagnarelli, P. (2015) 'Repo-Man is a multifunctional protein that regulates heterochromatin assembly and structure'.20th International Chromosome Conference (ICC). Univ Kent, Canterbury, ENGLAND. 1 - 4 September. SPRINGER. pp. 373 - 373. ISSN: 0967-3849

Conference paper

Booth, DG., Petfalsk, E., Tollervey, D., Earnshaw, WC. and Vagnarelli, P. (2015) 'Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery'.20th International Chromosome Conference (ICC). Univ Kent, Canterbury, ENGLAND. 1 - 4 September. SPRINGER. pp. 373 - 373. ISSN: 0967-3849

Conference paper

Gokhan, E., Page, R., Peti, W. and Vagnarelli, P. (2015) 'The Repo-Mann/PP1 complex structure and regulation'.20th International Chromosome Conference (ICC). Univ Kent, Canterbury, ENGLAND. 1 - 4 September. SPRINGER. pp. 387 - 388. ISSN: 0967-3849

Conference paper

Booth, DG., Takagi, M., Sanchez-Puilido, L., Petfalski, E., Vargiu, G., Samejima, K., et al. (2014) 'Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery.'.ASCB/IFCB Meeting. Philadelphia, PA. 1 - 10 December. AMER SOC CELL BIOLOGY. pp. 373 - 373. ISSN: 1059-1524

Conference paper

Castro, I., Budzak, J., Di Giacinto, ML., Foster, H., Reynolds, A., Ullman, KS. and et al. (2014) 'Repo-Man is a repressive chromatin modulator in the interphase nuclei'.ASCB/IFCB Meeting. Philadelphia, PA. 1 - 10 December. AMER SOC CELL BIOLOGY. ISSN: 1059-1524

Conference paper

Booth, DG., Takagi, M., Sanchez-Pulido, L., Petfalski, E., Vargiu, G., Samejima, K., et al. (2014) 'Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery'. eLife, 3 (3). pp. e01641. ISSN: 2050-084X Open Access Link

Journal article

Vagnarelli, P. (2014) 'Repo-man at the intersection of chromatin remodelling, DNA repair, nuclear envelope organization, and cancer progression'. Advances in Experimental Medicine and Biology, 773. pp. 401 - 414. ISSN: 0065-2598

Journal article

Meadows, JC., Graumann, K., Platani, M., Schweizer, N., Shimi, T., Vagnarelli, P. and et al. (2013) 'Meeting report: Mitosis and nuclear structure'. Journal of Cell Science, 126 (22). pp. 5087 - 5090. ISSN: 0021-9533

Journal article

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