Identification of molecular link between telomeres and telomerase and investigation of the mechanism underlying telomerase recruitment and activation
Funder: Cancer Research UKDuration: December 2010 - August 2017
People
| Name | Telephone | Office | ||
|---|---|---|---|---|
|
Dr Kazunori Tomita Senior Lecturer in Biomedical Sciences (Principal investigator)
E: kazunori.tomita@brunel.ac.uk
|
kazunori.tomita@brunel.ac.uk | Heinz Wolff 226 |
Outputs
Goncalves, T., Zoumpoulidou, G., Alvarez-Mendoza, C., Mancusi, C., Collopy, L., Strauss, S., et al. (2020) 'Selective Elimination of Osteosarcoma Cell Lines with Short Telomeres by Ataxia Telangiectasia and Rad3-Related Inhibitors'. ACS Pharmacology & Translational Science, 3 (6). pp. 1253 - 1264. ISSN: 2575-9108 Open Access Link
Balogh, E., Chandler, JC., Varga, M., Tahoun, M., Menyhárd, DK., Schay, G., et al. (2020) 'Pseudouridylation defect due to DKC1 and NOP10 mutations causes nephrotic syndrome with cataracts, hearing impairment, and enterocolitis'. Proceedings of the National Academy of Sciences, 117 (26). pp. 1 - 42. ISSN: 0027-8424 Open Access Link
Collopy, LC. and Tomita, K. (2019) 'Telomerase and immortalisation', in Pezzella, F., Tavassoli, M. and Kerr, D. (eds.) Oxford Textbook of Cancer Biology. Oxford University Press. , 1. pp. 209 - 220. ISBN 10: 0198779453. ISBN 13: 9780198779452.
Tomita, K. and Collopy, LC. (2018) 'Telomeres, Telomerase, and Cancer', in Boffetta, P. and Hainaut, P. (eds.) Encyclopedia of Cancer, 3rd edition. Academic Press. , 3. pp. 437 - 454. ISBN 10: 0128124849. ISBN 13: 9780128012383.
Tummala, H., Collopy, LC., Walne, AJ., Ellison, A., Cardoso, S., Aksu, T., et al. (2018) 'Homozygous OB-fold variants in telomere protein TPP1 are associated with dyskeratosis congenita–like phenotypes'. Blood, 132 (12). pp. 1349 - 1353. ISSN: 0006-4971 Open Access Link
Tomita, K. (2018) 'How long does telomerase extend telomeres? Regulation of telomerase release and telomere length homeostasis'. Current Genetics, 64 (6). pp. 1177 - 1181. ISSN: 0172-8083 Open Access Link
Collopy, LC., Ware, TL., Goncalves, T., Í Kongsstovu, S., Yang, Q., Amelina, H., et al. (2018) 'LARP7 family proteins have conserved function in telomerase assembly'. Nature Communications, 9 (1). pp. 1 - 8. ISSN: 2041-1723 Open Access Link
Armstrong, CA., Moiseeva, V., Collopy, LC., Pearson, SR., Ullah, TR., Xi, ST., et al. (2017) 'Fission yeast Ccq1 is a modulator of telomerase activity'. Nucleic Acids Research, 46 (2). pp. 704 - 716. ISSN: 0305-1048 Open Access Link
Armstrong, CA. and Tomita, K. (2017) 'Fundamental mechanisms of telomerase action in yeasts and mammals: Understanding telomeres and telomerase in cancer cells'. Open Biology, 7 (3). pp. 1 - 13. ISSN: 2046-2441 Open Access Link
Amelina, H., Moiseeva, V., Collopy, LC., Pearson, SR., Armstrong, CA. and Tomita, K. (2016) 'Sequential and counter-selectable cassettes for fission yeast'. BMC Biotechnology, 16 (1). pp. 1 - 15. ISSN: 1472-6750 Open Access Link