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The Role of Genetic, Epigenetic and Transcriptional Heterogeneities in Pre-leukaemia to Leukaemia Progression in AML

Funder: Lady Tata Memorial Trust
Duration: October 2017 - September 2020

PhD Studentship to Shikha Gupta (University of Cambridge)

People

Name Telephone Email Office
Dr Cristina Correia Antunes Pina Dr Cristina Correia Antunes Pina
Senior Lecturer in Biomedical Sciences
T: +44 (0)1895 266676
E: cristina.pina@brunel.ac.uk
+44 (0)1895 266676 cristina.pina@brunel.ac.uk Heinz Wolff 229

Outputs

Gupta, S., Dovey, OM., Domingues, AF., Cyran, OW., Cash, CM., Giotopoulos, G., et al. (2022) 'Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis'. Science advances, 8 (31). pp. 1 - 15. ISSN: 2375-2548 Open Access Link

Journal article

Domingues, AF., Kulkarni, R., Giotopoulos, G., Gupta, S., Vinnenberg, L., Arede, L., et al. (2020) 'Loss of Kat2a Enhances Transcriptional Noise and depletes Acute Myeloid Leukaemia Stem-like Cells'. eLife, 9. pp. 1 - 29. ISSN: 2050-084X Open Access Link

Journal article

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