Linking Metabolism and Epigenetics in Acute Myeloid Leukaemia
Funder: Leuka (Leukaemia UK)Duration: June 2017 - June 2019
John Goldman Fellowship for Future Science
People
| Name | Telephone | Office | ||
|---|---|---|---|---|
|
Dr Cristina Correia Antunes Pina Senior Lecturer in Biomedical Sciences (Principal investigator)
T: +44 (0)1895 266676
E: cristina.pina@brunel.ac.uk |
+44 (0)1895 266676 | cristina.pina@brunel.ac.uk | Heinz Wolff 229 |
Outputs
Zeka, K., Taylor, AV., Samarista, R., Ragusa, D., Suen, C-W., Cyran, OC., et al. (2023) 'MAT2A inhibition in AML unveils therapeutic potential of combining DNA demethylating agents with UPR targeting'. BiorXiv. pp. 1 - 20.Open Access Link
Ragusa, D., Suen, C-W., Torregrosa Cortes, G., Dijkhuis, L., Byrne, C., Ionescu, G-A., et al. (2022) 'Dissecting infant leukemia developmental origins with a hemogenic gastruloid model'. biorXiv. pp. 1 - 43.Open Access Link
Gupta, S., Dovey, OM., Domingues, AF., Cyran, OW., Cash, CM., Giotopoulos, G., et al. (2022) 'Transcriptional variability accelerates pre-leukemia by cell diversification and perturbation of protein synthesis'. Science advances, 8 (31). pp. 1 - 15. ISSN: 2375-2548 Open Access Link
Arede, L., Foerner, E., Wind, S., Kulkarni, R., Domingues, AF., Giotopoulos, G., et al. (2021) 'KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia'. Blood advances, 6 (1). pp. 165 - 180. ISSN: 2473-9529 Open Access Link