Dr Sara Anjomani Virmouni
Senior Lecturer in Biomedical Sciences
- Email: sara.anjomanivirmouni@brunel.ac.uk
- Tel: +44 (0)1895 268165
Research area(s)
Neurodegenerative diseases, Friedreich’s ataxia, Epigenetics and Metabolomics
Research Interests
The Ataxia Research Group investigates molecular disease mechanisms and therapy for the inherited disorder, Friedreich’s ataxia (FRDA). Currently, the lab is focused on five projects:
- Metabolomics analysis of FRDA cells
- Proteome/phosphoproteome analysis of FRDA cells
- Cell and gene therapy for FRDA
- Therapeutic potential of different antioxidants in FRDA
- Development and characterisation of GAA repeat-based FRDA transgenic mouse models
Team:
Senior Research Fellow
- Dr Sahar Al-Mahdawi
Postdoctoral Researcher
- Dr Saqlain Suleman
PhD Students
- Mr Fred Edzeamey
- Ms Zeynep Ulukutuk
- MS Zenouska Ramchunder
Research grants and projects
Research Projects
Grants
Advancing new therapies for Friedreich ataxia heart disease
Funder: National Health and Medical Research Council
Duration: February 2024 - February 2027
Funder: National Health and Medical Research Council
Duration: February 2024 - February 2027
Effect of targeting sphingolipid-metabolising enzymes in iPSC-derived sensory neurons obtained from FRDA patients
Funder: Ataxia UK
Duration: January 2024 -
Funder: Ataxia UK
Duration: January 2024 -
Haematopoietic stem cells gene therapy for the treatment of Friedreich’s Ataxia
Funder: Friedreich’s Ataxia Research Alliance (FARA)
Duration: January 2022 - January 2024
Funder: Friedreich’s Ataxia Research Alliance (FARA)
Duration: January 2022 - January 2024
Sphingolipid Rheostat as a Potential Target for Friedreich’s Ataxia
Funder: Friedreich's Ataxia Research Alliance
Duration: October 2021 - October 2023
Funder: Friedreich's Ataxia Research Alliance
Duration: October 2021 - October 2023
Investigating the role of bioactive sphingolipids in Friedreich’s ataxia (FRDA)
Funder: Ataxia UK
Duration: January 2021 - July 2021
Funder: Ataxia UK
Duration: January 2021 - July 2021
Project Grant
Comprehensive phosphoproteome analysis of Friedreich’s ataxia cells
Funder: Brunel BRIEF Award
Duration: September 2019 - September 2021
Funder: Brunel BRIEF Award
Duration: September 2019 - September 2021
A new cell and gene therapy approach for Friedreich's ataxia
Funder: Medical Research Council
Duration: May 2019 - April 2021
Funder: Medical Research Council
Duration: May 2019 - April 2021
Elucidation of the metabolic signature of Friedreich’s ataxia
Funder: FARA-US
Duration: April 2018 - June 2021
Funder: FARA-US
Duration: April 2018 - June 2021