
Professor Arturo Sala
Professor
Heinz Wolff 123A
- Email: arturo.sala@brunel.ac.uk
- Tel: +44 (0)1895 265547
Bibbò, S., Capone, E., Lovato, G., Lamolinara, A., Ponziani, S., Iezzi, M., et al. (2024) 'EV20/Omomyc: A novel dual MYC/HER3 targeting immunoconjugate'. Journal of Controlled Release, 374. pp. 171 - 180. ISSN: 0168-3659
Cicirò, Y., Ragusa, D. and Sala, A. (2024) 'Expression of the checkpoint kinase BUB1 is a predictor of response to cancer therapies'. Scientific Reports, 14 (1). pp. 1 - 15. ISSN: 2045-2322
Cicirò, Y., Ragusa, D., Tejera Nevado, P., Lattanzio, R., Sala, G., DesRochers, T., et al. (2023) 'The mitotic checkpoint kinase BUB1 is a direct and actionable target of MYB in adenoid cystic carcinoma'. FEBS Letters, 598 (2). pp. 252 - 265. ISSN: 0014-5793
Tsakaneli, A., Carregari, VC., Morini, M., Eva, A., Cangemi, G., Chayka, O., et al. (2022) 'MYC regulates metabolism through vesicular transfer of glycolytic kinases'. Open Biology, 11 (12). pp. 1 - 15. ISSN: 2046-2441
Tagalakis, AD., Jayarajan, V., Maeshima, R., Ho, KH., Syed, F., Wu, L-P., et al. (2021) 'Integrin-Targeted, Short Interfering RNA Nanocomplexes for Neuroblastoma Tumor-Specific Delivery Achieve MYCN Silencing with Improved Survival'. Advanced Functional Materials, 31 (37). pp. 1 - 12. ISSN: 1616-301X
Cicirò, Y. and Sala, A. (2021) 'MYB oncoproteins: emerging players and potential therapeutic targets in human cancer'. Oncogenesis, 10 (2). pp. 1 - 15. ISSN: 2157-9024
Capone, E., Lamolinara, A., Pastorino, F., Gentile, R., Ponziani, S., Di Vittorio, G., et al. (2020) 'Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma'. Cancers, 12 (10). pp. 1 - 18. ISSN: 2072-6694
Andersson, MK., Mangiapane, G., Nevado, PT., Tsakaneli, A., Carlsson, T., Corda, G., et al. (2020) 'ATR is a MYB regulated gene and potential therapeutic target in adenoid cystic carcinoma'. Oncogenesis, 9 (1). pp. 5. ISSN: 2157-9024
Karteris, E., Nieddu, V., Piredda, R., Bexel, D., Barton, J., Anderson, J., et al. (2019) 'Engineered human mesenchymal stem cells for neuroblastoma therapeutics'. Oncology Reports, 42 (1). pp. 1 - 8. ISSN: 1021-335X
Capone, E., Piccolo, E., Fichera, I., Ciufici, P., Barcaroli, D., Sala, A., et al. (2017) 'Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma.'. Oncotarget, 8 (36). pp. 60368 - 60377. ISSN: 1949-2553
Sala, A. (2017) 'Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma'. Oncotarget, 8 (36). pp. 60368 - 60377. ISSN: 1949-2553
Sala, A. and corda, G. (2017) 'Non-canonical WNT/PCP signalling in cancer: Fzd6 takes centre stage.'. Oncogenesis, 6 (7). pp. e364. ISSN: 2157-9024
Corda, G., Sala, G., Lattanzio, R., Iezzi, M., Sallese, M., Fragassi, G., et al. (2016) 'Functional and prognostic significance of the genomic amplification of frizzled receptor 6 ( FZD6 ) in breast cancer'. The Journal of Pathology, 241 (3). pp. 350 - 361. ISSN: 0022-3417
Corda, G. and Sala, A. (2016) 'Cutaneous cylindroma: it's all about MYB'. The Journal of Pathology, 29 (4). pp. 391 - 393. ISSN: 0022-3417
Dvorkina, M., Nieddu, V., Chakelam, S., Pezzolo, A., Cantilena, S., Leite, AP., et al. (2016) 'A promyelocytic leukemia protein-thrombospondin 2 axis and the risk of relapse in neuroblastoma.'. Clinical cancer research : an official journal of the American Association for Cancer Research, 22 (13). pp. 3398 - 3409. ISSN: 1078-0432
Sala, A. (2015) 'Editorial: Targeting MYCN in pediatric cancers'. Frontiers in Oncology, 5 (MAY). pp. 1 - 2. ISSN: 2234-943X
Chayka, O., D'Acunto, CW., Middleton, O., Arab, M. and Sala, A. (2014) 'Identification and pharmacological inactivation of the MYCN gene network as a therapeutic strategy for neuroblastic tumor cells'. Journal of Biological Chemistry, 290 (4). pp. 2198 - 2212. ISSN: 0021-9258
Santilli, G., Anderson, J., Thrasher, AJ. and Sala, A. (2013) 'Catechins and antitumor immunity: Not MDSC's cup of tea'. OncoImmunology, 2 (6). pp. e24443 - e24443. ISSN: 2162-4011
Corvetta, D., Chayka, O., Gherardi, S., D'Acunto, CW., Cantilena, S., Valli, E., et al. (2013) 'Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: Functional and therapeutic implications'. Journal of Biological Chemistry, 288 (12). pp. 8332 - 8341. ISSN: 0021-9258
Santilli, G., Thrasher, AJ., Piotrowska, I., Cantilena, S., Chayka, O., D'Alicarnasso, M., et al. (2013) 'Polyphenon E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells'. Clinical Cancer Research, 19 (5). pp. 1116 - 1125. ISSN: 1078-0432
Sala, A. (2012) 'c-MYB and TGF-β: EMT's dynamic duo in breast cancer'. Cell Cycle, 11 (1). pp. 17. ISSN: 1538-4101
Sottile, F., Gnemmi, I., Cantilena, S., D'Acunto, WC. and Sala, A. (2012) 'A chemical screen identifies the chemotherapeutic drug topotecan as a specific inhibitor of the B-MYB/MYCN axis in neuroblastoma'. Oncotarget, 3 (5). pp. 535 - 545. ISSN: 1949-2553
Cantilena, S., Pastorino, F., Pezzolo, A., Chayka, O., Pistoia, V., Ponzoni, M. and et al. (2011) 'Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas'. Oncotarget, 2 (12). pp. 976 - 983. ISSN: 1949-2553
Chaiwatanasirikul, K-A. and Sala, A. (2011) 'The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60'. Cell Death and Disease, 2 (10). ISSN: 2041-4889
Chaiwatanasirikul, KA. and Sala, A. (2011) 'The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60'. Cell Death and Disease. ISSN: 2041-4889
Gualdrini, F., Corvetta, D., Cantilena, S., Chayka, O., Tanno, B., Raschellà, G. and et al. (2010) 'Addiction of MYCN amplified tumours to B-MYB underscores a reciprocal regulatory loop'. Oncotarget, 1 (4). pp. 278 - 288. ISSN: 1949-2553
Bettuzzi, S., Davalli, P., Davoli, S., Chayka, O., Rizzi, F., Belloni, L., et al. (2009) 'Genetic inactivation of ApoJ/clusterin: Effects on prostate tumourigenesis and metastatic spread'. Oncogene, 28 (49). pp. 4344 - 4352. ISSN: 0950-9232
Sala, A., Bettuzzi, S., Pucci, S., Chayka, O., Dews, M. and Thomas-Tikhonenko, A. (2009) 'Regulation of CLU gene expression by oncogenes and epigenetic factors implications for tumorigenesis'. Advances in Cancer Research, 105 (1). pp. 115 - 132. ISSN: 0065-230X
Chayka, O., Corvetta, D., Dews, M., Caccamo, AE., Piotrowska, I., Santilli, G., et al. (2009) 'Clusterin, a haploinsufficient tumor suppressor gene in neuroblastomas'. Journal of the National Cancer Institute, 101 (9). pp. 663 - 677. ISSN: 0027-8874
Schwab, R., Bussolari, R., Corvetta, D., Chayka, O., Santilli, G., Kwok, JM., et al. (2008) 'Isolation and functional assessment of common, polymorphic variants of the B-MYB proto-oncogene associated with a reduced cancer risk'. Oncogene, 27 (20). pp. 2929 - 2933. ISSN: 0950-9232
Schwab, R., Caccamo, A., Bettuzzi, S., Anderson, J. and Sala, A. (2007) 'B-MYB is hypophosphorylated and resistant to degradation in neuroblastoma: Implications for cell survival'. Blood Cells, Molecules, and Diseases, 39 (3). pp. 263 - 271. ISSN: 1079-9796
Santilli, G., Aronow, BJ. and Sala, A. (2003) 'Essential requirement of apolipoprotein J (clusterin) signaling for IkappaB expression and regulation of NF-kappaB activity'. Journal of Biological Chemistry, 278 (40). pp. 38214 - 38219. ISSN: 0021-9258